Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Darius Moharregh-Khiabani"'
Autor:
Viktoria Gudi, Jelena Škuljec, Özlem Yildiz, Konstantin Frichert, Thomas Skripuletz, Darius Moharregh-Khiabani, Elke Voss, Kirsten Wissel, Sabine Wolter, Martin Stangel
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22623 (2011)
Demyelination is the cause of disability in various neurological disorders. It is therefore crucial to understand the molecular regulation of oligodendrocytes, the myelin forming cells in the CNS. Growth factors are known to be essential for the deve
Externí odkaz:
https://doaj.org/article/e4b4c8b5b7f04cfba2dc7c790ca680db
Autor:
Darius Moharregh-Khiabani, Alexander Blank, Thomas Skripuletz, Elvira Miller, Alexandra Kotsiari, Viktoria Gudi, Martin Stangel
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11769 (2010)
BACKGROUND: Fumaric acid esters (FAE) are a group of compounds which are currently under investigation as an oral treatment for relapsing-remitting multiple sclerosis. One of the suggested modes of action is the potential of FAE to exert a neuroprote
Externí odkaz:
https://doaj.org/article/62e6ae54c41344dca040b583a5ac2add
Autor:
Elvira Miller, Viktoria Gudi, Darius Moharregh-Khiabani, Lisa Grote, Martin Stangel, Jelena Skuljec, Elke Voss, Corinna Trebst, Refik Pul, Thomas Skripuletz
Publikováno v:
Brain, Behavior, and Immunity
Systemic infection can influence the course in many diseases of the central nervous system (CNS) such as multiple sclerosis (MS), yet the relationship between infection outside the CNS and potential damage and/or protection within the CNS is still no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83011403c6cf4bf90376060fc6985d2f
https://doi.org/10.1016/j.bbi.2011.05.009
https://doi.org/10.1016/j.bbi.2011.05.009
Autor:
Jens-Heiko Bussmann, Martin Stangel, Darius Moharregh-Khiabani, Maren Lindner, Refik Pul, Thomas Skripuletz, Viktoria Gudi, Paraskevi N. Koutsoudaki
Publikováno v:
Brain Pathol
In multiple sclerosis, demyelination occurs beside the white‐matter structures and in the cerebral and cerebellar cortex. We have previously shown that, in the cuprizone model, demyelination is present not only in the corpus callosum but also in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b3bbf8960ea5a9f5dd05ba95c8d539
https://doi.org/10.1111/j.1750-3639.2009.00271.x
https://doi.org/10.1111/j.1750-3639.2009.00271.x
Autor:
H. J. Hecht, C. Erck, Andreas Jeron, R. Roubin, T. P. Arstila, Eliisa Kekäläinen, Siegfried Weiss, K. Wagner, Henk S.P. Garritsen, Darius Moharregh-Khiabani, Hansjörg Hauser, Jan Buer, Robert Geffers, Michael Probst-Kepper, Frank Ocklenburg, Rudi Balling, N. Viegas, Andrea Kröger, H. Lünsdorf
Publikováno v:
Journal of Cellular and Molecular Medicine
Recent evidence suggests that regulatory pathways might control sustained high levels of FOXP3 in regulatory CD4(+)CD25(hi) T (T(reg)) cells. Based on transcriptional profiling of ex vivo activated T(reg) and helper CD4(+)CD25(-) T (T(h)) cells we ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd2ba015f0890f5b05d8e62faec490c
http://europepmc.org/articles/PMC4516490
http://europepmc.org/articles/PMC4516490
Autor:
Paraskevi N. Koutsoudaki, Herbert Hildebrandt, Martin Stangel, Thomas Skripuletz, Corinna Trebst, Darius Moharregh-Khiabani, Viktoria Gudi
Publikováno v:
Neuroscience Letters. 451:83-88
In multiple sclerosis demyelination not only affects the white matter, but also the grey matter of the brain. We have previously reported that in the murine cuprizone model for demyelination lesions occur in addition to the corpus callosum also in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e64456532271ebab6f499a9b698a34
https://doi.org/10.1016/j.neulet.2008.11.058
https://doi.org/10.1016/j.neulet.2008.11.058
Publikováno v:
Current Neuropharmacology
Fumaric acid is an intermediate product of the citric acid cycle that is a source of intracellular energy in the form of adenosine triphosphate (ATP). It is generated by oxidation of adenylsuccinate by the enzyme succinate dehydrogenase and is then c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0306e677348b1001c14f60d06a2aa901
http://europepmc.org/articles/PMC2724664
http://europepmc.org/articles/PMC2724664
Autor:
Grazia Mauceri, Wolfgang Engel, Andreas Meinhardt, Bernhard Vaske, Detlef Böhm, Anja Schöner, Stephanie Schubert, Ibrahim M. Adham, Kenji Kamino, Jörg Schmidtke, Daniela Gonzalez-Fassrainer, Darius Moharregh-Khiabani, Reinhard von Wasielewski
Publikováno v:
Biology of Reproduction. 79:125-133
TSPY (testis-specific protein, Y-encoded) genes are expressed in premeiotic germ cells and round spermatids. The topology and timing of TSPY expression, and also its homology to members of the TTSN-family, suggest that TSPY is a proliferation factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5379457e6687168f3777ed9a3d3279a1
https://doi.org/10.1095/biolreprod.107.067025
https://doi.org/10.1095/biolreprod.107.067025
Autor:
Juergen Klempnauer, Susanne Pfoertner, Lothar Groebe, Darius Moharregh-Khiabani, Siegfried Weiss, Robert Geffers, Frank Ocklenburg, Jan Buer, Viktoria Janke, Michael Probst-Kepper, Henk S.P. Garritsen, Kurt E.J. Dittmar
Publikováno v:
Laboratory Investigation. 86:724-737
Here, we report the identification of the ubiquitin-like gene UBD as a downstream element of FOXP3 in human activated regulatory CD4(+)CD25(hi) T cells (T(reg)). Retroviral transduction of UBD in human allo-reactive effector CD4(+) T helper (T(h)) ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fc217b60b758ba73cd63dd4ffcb18c
https://doi.org/10.1038/labinvest.3700432
https://doi.org/10.1038/labinvest.3700432
Autor:
Karelle Bénardais, Alexandra Kotsiari, Refik Pul, Daniela Ragancokova, Darius Moharregh-Khiabani, Jelena Skuljec, Hui Sun, Martin Stangel, Corinna Trebst
Publikováno v:
Cellular Immunology; Vol 270
The chemokine receptors CCR1, CCR2, CCR3, CCR5, and CXCR2 have been found to be expressed on microglia in many neurodegenerative diseases, such as multiple sclerosis and Alzheimer's disease. There is emerging evidence that chemokines, besides chemoat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0d9cd2cccb9ffd196ab7909defb7f7
https://pubmed.ncbi.nlm.nih.gov/21620385
https://pubmed.ncbi.nlm.nih.gov/21620385