Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Dario Romagnoli"'
Autor:
Matteo Benelli, Gian Marco Franceschini, Alberto Magi, Dario Romagnoli, Chiara Biagioni, Ilenia Migliaccio, Luca Malorni, Francesca Demichelis
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Matteo Benelli et al. present Rocker-meth, a new Hidden Markov Model (HMM)-based method, to robustly identify differentially methylated regions (DMRs). They use Rocker-meth to analyse more than 6000 methylation profiles across 14 cancer types, provid
Externí odkaz:
https://doaj.org/article/2d3834fd736a4fd896630a6f3d833ab9
Autor:
Francesca Galardi, Francesca De Luca, Chiara Biagioni, Ilenia Migliaccio, Giuseppe Curigliano, Alessandro M. Minisini, Martina Bonechi, Erica Moretti, Emanuela Risi, Amelia McCartney, Matteo Benelli, Dario Romagnoli, Silvia Cappadona, Stefano Gabellini, Cristina Guarducci, Valerio Conti, Laura Biganzoli, Angelo Di Leo, Luca Malorni
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Circulating tumor cells (CTCs) are prognostic in patients with advanced breast cancer (ABC). However, no data exist about their use in patients treated with palbociclib. We analyzed the prognostic role of CTC counts in patients en
Externí odkaz:
https://doaj.org/article/2bff5be9c34644208616c14bb489fbff
Autor:
Valentina Profumo, Barbara Forte, Stefano Percio, Federica Rotundo, Valentina Doldi, Elena Ferrari, Nicola Fenderico, Matteo Dugo, Dario Romagnoli, Matteo Benelli, Riccardo Valdagni, Diletta Dolfini, Nadia Zaffaroni, Paolo Gandellini
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
miR-205 is known to have context-dependent tumor suppressive or oncogenic roles. Here, the authors report the host gene of miR-205, MIR205HG as a nuclear lincRNA that maintains the basal identity of prostate cell and prevents luminal cell differentia
Externí odkaz:
https://doaj.org/article/3732cd911d6749edbdf73c6627e1003f
Autor:
Dario Romagnoli, Giulia Boccalini, Martina Bonechi, Chiara Biagioni, Paola Fassan, Roberto Bertorelli, Veronica De Sanctis, Angelo Di Leo, Ilenia Migliaccio, Luca Malorni, Matteo Benelli
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background New single-cell isolation technologies are facilitating studies on the transcriptomics of individual cells. Bio-Rad ddSEQ is a droplet-based microfluidic system that, when coupled with downstream Illumina library preparation and s
Externí odkaz:
https://doaj.org/article/0d898050a05d4d97b1f8ffa86ecd52a2
Autor:
Emanuela Risi, Chiara Biagioni, Matteo Benelli, Ilenia Migliaccio, Amelia McCartney, Martina Bonechi, Cristina Guarducci, Florentine Hilbers, Serena Di Cosimo, Jens Huober, Dario Romagnoli, Giulia Boccalini, Stefania Vitale, Christos Sotiriou, Laura Biganzoli, Angelo Di Leo, Luca Malorni
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Chemotherapy added to anti-HER2 agents (H) is the treatment of choice in patients with HER2+ early breast cancer. However, HER2+ tumours are clinically and biologically heterogeneous, and treatment response varies significantly by hormone
Externí odkaz:
https://doaj.org/article/9bb800b4b1f647df9d8ccc1075ba0f5b
Autor:
Alessia Vignoli, Elena Mori, Samantha Di Donato, Luca Malorni, Chiara Biagioni, Matteo Benelli, Vanessa Calamai, Stefano Cantafio, Annamaria Parnofiello, Maddalena Baraghini, Alessia Garzi, Francesca Del Monte, Dario Romagnoli, Ilenia Migliaccio, Claudio Luchinat, Leonardo Tenori, Laura Biganzoli
Publikováno v:
Applied Sciences, Vol 11, Iss 23, p 11120 (2021)
Background: Colorectal cancer (CRC) is the fourth most commonly diagnosed and third most deadly cancer worldwide. Surgery is the main treatment option for early disease; however, a relevant proportion of CRC patients relapse. Here, variations among p
Externí odkaz:
https://doaj.org/article/a93d6efcf0ca42219c2175a320e56715
Autor:
Amelia McCartney, Ilenia Migliaccio, Martina Bonechi, Chiara Biagioni, Dario Romagnoli, Francesca De Luca, Francesca Galardi, Emanuela Risi, Irene De Santo, Matteo Benelli, Luca Malorni, Angelo Di Leo
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The recent arrival of CDK4/6 inhibitor agents, with an approximate doubling of progression-free survival (PFS) associated with their use in hormone receptor-positive, HER2-negative advanced breast cancer (BC), has radically changed the approach to ma
Externí odkaz:
https://doaj.org/article/01a7b964ad544666af93b70edebf3015
Autor:
Francesca Galardi, Francesca De Luca, Dario Romagnoli, Chiara Biagioni, Erica Moretti, Laura Biganzoli, Angelo Di Leo, Ilenia Migliaccio, Luca Malorni, Matteo Benelli
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1677 (2020)
Liquid biopsy based on cell-free DNA (cfDNA) enables non-invasive dynamic assessment of disease status in patients with cancer, both in the early and advanced settings. The analysis of DNA-methylation (DNAm) from cfDNA samples holds great promise due
Externí odkaz:
https://doaj.org/article/524551d27157468d9820a1ff32acf35d
Autor:
Emanuela Risi, Marta Pestrin, Chiara Biagioni, Dario Romagnoli, Ilenia Migliaccio, Francesca Galardi, Francesca De Luca, Matteo Benelli, Erica Moretti, Giuseppina Sanna, Luca Livraghi, Silvia Cappadona, Roberta Di Marsico, Domenico Amoroso, Angelo Martignetti, Angela S. Ribecco, Elena Rota Caremoli, Luigi Coltelli, Fabio Puglisi, Luca Malorni, Laura Biganzoli
Publikováno v:
Cancer Research. 83:P3-05
Background: In the era of targeted therapies, chemotherapy (CT) is still a valuable treatment option for patients (pts) with HER2 negative metastatic breast cancer (MBC). The identification of predictive and prognostic markers might improve treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22801bf17539ee8cc252b4f11dca3802
https://doi.org/10.1158/1538-7445.sabcs22-p3-05-45
https://doi.org/10.1158/1538-7445.sabcs22-p3-05-45
Autor:
Silvia Giordano, Simona Corso, Caterina Marchiò, Alessandro Ferrero, Marco F. Amisano, Gian Luca Baiocchi, Maurizio Degiuli, Giovanni De Manzoni, Uberto Fumagalli, Maria Antista, Federica Morano, Michele Prisciandaro, Andrea Sartore-Bianchi, Salvatore Siena, Antonino Musolino, Alba Llop-Guevara, Benedetta Pellegrino, Violeta Serra, Elisabetta Puliga, Irene M. Maina, Daniela Conticelli, Cristina Migliore, Daniel Moya-Rull, Salvatore Ribisi, Claudia Orrù, Enrico Berrino, Dario Romagnoli, Loris De Cecco, Matteo Benelli, Sara E. Bellomo, Filippo Pietrantonio, Sabrina Rizzolio, Annalisa Petrelli
A gastric cancer PDX model carrying two LOF mutations in the ATM gene is not responsive to olaparib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc90fba163a85c6afb15ea9f43f773fa
https://doi.org/10.1158/0008-5472.22820333
https://doi.org/10.1158/0008-5472.22820333
