Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dario Priem"'
Autor:
Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu J. M. Bertrand
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-11 (2023)
Abstract Plasma membrane permeabilization (PMP) is a defining feature of regulated necrosis. It allows the extracellular release of damage-associated molecular patterns (DAMPs) that trigger sterile inflammation. The pore forming molecules MLKL and GS
Externí odkaz:
https://doaj.org/article/1ff3b99cfe634013862ac454cf77c92d
Autor:
Karel F. A. Van Damme, Pieter Hertens, Arne Martens, Elisabeth Gilis, Dario Priem, Inge Bruggeman, Amelie Fossoul, Jozefien Declercq, Helena Aegerter, Andy Wullaert, Tino Hochepied, Esther Hoste, Lieselotte Vande Walle, Mohamed Lamkanfi, Savvas N. Savvides, Dirk Elewaut, Bart N. Lambrecht, Geert van Loo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract A20 serves as a critical brake on NF-κB-dependent inflammation. In humans, polymorphisms in or near the TNFAIP3/A20 gene have been linked to various inflammatory disorders, including systemic lupus erythematosus (SLE) and rheumatoid arthrit
Externí odkaz:
https://doaj.org/article/0bf2e4c99bae45e2afbc4924a4035aa2
Autor:
Tom Delanghe, Jon Huyghe, Seungheon Lee, Dario Priem, Samya Van Coillie, Barbara Gilbert, Sze Men Choi, Peter Vandenabeele, Alexei Degterev, Gregory D. Cuny, Yves Dondelinger, Mathieu J. M. Bertrand
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Abstract Butylate hydroxyanisole (BHA) is a synthetic phenol that is widely utilized as a preservative by the food and cosmetic industries. The antioxidant properties of BHA are also frequently used by scientists to claim the implication of reactive
Externí odkaz:
https://doaj.org/article/9448bec40ee64a8caab6d27a339306b6
Autor:
Yves Dondelinger, Tom Delanghe, Dario Priem, Meghan A. Wynosky-Dolfi, Daniel Sorobetea, Diego Rojas-Rivera, Piero Giansanti, Ria Roelandt, Julia Gropengiesser, Klaus Ruckdeschel, Savvas N. Savvides, Albert J. R. Heck, Peter Vandenabeele, Igor E. Brodsky, Mathieu J. M. Bertrand
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
RIPK1 kinase activity is known to transduce a death signal, but the molecular mechanisms that normally prevent RIPK1 activation are unclear. Here, the authors report that IKK-mediated phosphorylation on RIPK1 Ser25 directly represses its enzymatic ac
Externí odkaz:
https://doaj.org/article/09b6a96e862a47278fdf07e7af978602
Autor:
Lien Verboom, Arne Martens, Dario Priem, Esther Hoste, Mozes Sze, Hanna Vikkula, Lisette Van Hove, Sofie Voet, Jana Roels, Jonathan Maelfait, Laura Bongiovanni, Alain de Bruin, Charlotte L. Scott, Yvan Saeys, Manolis Pasparakis, Mathieu J.M. Bertrand, Geert van Loo
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2237-2247.e6 (2020)
Summary: Inflammatory signaling pathways are tightly regulated to avoid chronic inflammation and the development of disease. OTULIN is a deubiquitinating enzyme that controls inflammation by cleaving linear ubiquitin chains generated by the linear ub
Externí odkaz:
https://doaj.org/article/1511e219df8c4f228d716b7cc3be84c8
Publikováno v:
Autophagy. :1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddb5072ae279097c5ecdbf4911837ff6
https://doi.org/10.1080/15548627.2023.2197760
https://doi.org/10.1080/15548627.2023.2197760
Autor:
Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Yasuo Uchiyama, Esther Hoste, Geert van Loo, Mathieu J. M. Bertrand
Publikováno v:
Science (New York, N.Y.). 378(6625)
Cell death induced by tumor necrosis factor (TNF) can be beneficial during infection by helping to mount proper immune responses. However, TNF-induced death can also drive a variety of inflammatory pathologies. Protectives brakes, or cell-death check
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5667924d6f1e42708344fed2b2d0c0b0
https://pubmed.ncbi.nlm.nih.gov/36520901
https://pubmed.ncbi.nlm.nih.gov/36520901
Autor:
Arne Martens, Pieter Hertens, Dario Priem, Vagelis Rinotas, Theodore Meletakos, Meropi Gennadi, Lisette Van Hove, Els Louagie, Julie Coudenys, Amélie De Muynck, Djoere Gaublomme, Mozes Sze, Jolanda van Hengel, Leen Catrysse, Esther Hoste, Jeffrey D Zajac, Rachel A Davey, Luc Van Hoorebeke, Tino Hochepied, Mathieu J M Bertrand, Marietta Armaka, Dirk Elewaut, Geert van Loo
Publikováno v:
EMBO REPORTS
The anti-inflammatory protein A20 serves as a critical brake on NF-kappa B signaling and NF-kappa B-dependent inflammation. In humans, polymorphisms in or near the TNFAIP3/A20 gene have been associated with several inflammatory disorders, including r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596c86a6ad332cdef551c4b46dd0e5da
https://doi.org/10.15252/embr.202255233
https://doi.org/10.15252/embr.202255233
Publikováno v:
Trends in Immunology. 41:421-435
A20 is a potent anti-inflammatory molecule, and mutations in TNFAIP3, the gene encoding A20, are associated with a wide panel of inflammatory pathologies, both in human and mouse. The anti-inflammatory properties of A20 are commonly attributed to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aab1232482f9cf91b60a60b3964ab0e
https://doi.org/10.1016/j.it.2020.03.001
https://doi.org/10.1016/j.it.2020.03.001
Autor:
Mathieu J.M. Bertrand, Jon Huyghe, Tom Delanghe, Dario Priem, Alexei Degterev, Sze Men Choi, Yves Dondelinger, Samya Van Coillie, Barbara Gilbert, Gregory D. Cuny, Seungheon Lee, Peter Vandenabeele
Publikováno v:
Cell Death & Disease
CELL DEATH & DISEASE
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
CELL DEATH & DISEASE
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Butylate hydroxyanisole (BHA) is a synthetic phenol that is widely utilized as a preservative by the food and cosmetic industries. The antioxidant properties of BHA are also frequently used by scientists to claim the implication of reactive oxygen sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f5ff01f77653d2d27edb38e63f0152
https://doi.org/10.1038/s41419-021-03994-0
https://doi.org/10.1038/s41419-021-03994-0