Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dario Pacitti"'
Autor:
Bridget E. Bax, Dario Pacitti
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Externí odkaz:
https://doaj.org/article/bfebc6c9c090457e81074863121afe04
Autor:
Michelle Levene, Dario Pacitti, Charlotte Gasson, Jamie Hall, Marcia Sellos-Moura, Bridget E. Bax
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 11, Iss , Pp 1-8 (2018)
Erythrocyte encapsulated thymidine phosphorylase is recombinant Escherichia coli thymidine phosphorylase encapsulated within human autologous erythrocytes and is under development as an enzyme replacement therapy for the ultra-rare inherited metaboli
Externí odkaz:
https://doaj.org/article/3f454fa28ac74ca78eedd5841cfa3eb9
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
With 100 billion neurons and 100 trillion synapses, the human brain is not just the most complex organ in the human body, but has also been described as “the most complex thing in the universe.” The limited availability of human living brain tiss
Externí odkaz:
https://doaj.org/article/7d199d9ed22943c4aa3b7a8503c29495
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare metabolic autosomal recessive disease, caused by mutations in the nuclear gene TYMP which encodes the enzyme thymidine phosphorylase. The resulting enzyme deficiency leads
Externí odkaz:
https://doaj.org/article/c4bf83045c854b4e8d6dec00184aa009
Autor:
Peter A. B. Wark, Matthew Whiteman, Roberta Torregrossa, Dario Pacitti, Haroon Khan, Chris J. Scotton, Vinod Kumar, Philip M. Hansbro
Publikováno v:
Antioxidants & Redox Signaling. 35:551-579
Hydrogen sulfide (H2S) is a gaseous signaling molecule involved in a plethora of physiological and pathological processes. It is primarily synthesized by cystathionine-β-synthase, cystathionine-γ-lyase, and 3-mercaptopyruvate sulfurtransferase as a
Autor:
Roberta Torregrossa, Timothy Etheridge, Dario Pacitti, Csaba Szabó, Bridget Fox, Luke Slade, Matthew Whiteman
Publikováno v:
Journal of Inherited Metabolic Disease. 44:367-375
Primary mitochondrial diseases (PMD) are inherited diseases that cause dysfunctional mitochondrial oxidative phosphorylation, leading to diverse multisystem diseases and substantially impaired quality of life. PMD treatment currently comprises sympto
Autor:
Michelle Levene, Murray D. Bain, Nicholas F. Moran, Niranjanan Nirmalananthan, Joanna Poulton, Mauro Scarpelli, Massimiliano Filosto, Hanna Mandel, Andrew D. MacKinnon, Lynette Fairbanks, Dario Pacitti, Bridget E Bax
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 4, p 457 (2019)
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare autosomal recessive disorder of nucleoside metabolism that is caused by mutations in the nuclear thymidine phosphorylase gene (TYMP) gene, encoding for the enzyme thymidin
Externí odkaz:
https://doaj.org/article/cc460ec6c52647d1a2a3cb8329d7ee0a
Autor:
Jamie Hall, Marcia Sellos-Moura, Charlotte Gasson, Bridget E. Bax, Dario Pacitti, Michelle Levene
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 11, Iss, Pp 1-8 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods & Clinical Development
Erythrocyte encapsulated thymidine phosphorylase is recombinant Escherichia coli thymidine phosphorylase encapsulated within human autologous erythrocytes and is under development as an enzyme replacement therapy for the ultra-rare inherited metaboli
Autor:
Dario Pacitti, Bridget E. Bax
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 37:603-617
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare disorder caused by mutations in the thymidine phosphorylase gene (TYMP), leading to secondary aberrations to the mitochondrial genome. The disease is characterised by gastrointes
Autor:
V. Kumar, Philip M. Hansbro, Tatt Jhong Haw, Mark E. Wood, Nicole G. Hansbro, Chris J. Scotton, Dario Pacitti, L. Balachandran, Alexandra C. Brown, Matthew Whiteman, Roberta Torregrossa
Publikováno v:
A101. COPD TRANSLATIONAL STUDIES.