Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dario Motti"'
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e44764 (2023)
BackgroundDigital therapeutics (DTx) are software-based products that prevent, manage, or treat a medical condition and are delivered through a smartphone app, web application, or wearable device. Clinical trials assessing DTx pose challenges, foremo
Externí odkaz:
https://doaj.org/article/e01ad3b7a26b468c8fde0e089953e630
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 1, Pp 144-149 (2016)
Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Administration of post-surgical analgesics is an important consideration for animal welfare, but the actions of the analgesic must not int
Externí odkaz:
https://doaj.org/article/669e36fd9fdf4e5ea49e8c1d4e503dae
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30417 (2012)
To fully understand cell type identity and function in the nervous system there is a need to understand neuronal gene expression at the level of isoform diversity. Here we applied Next Generation Sequencing of the transcriptome (RNA-Seq) to purified
Externí odkaz:
https://doaj.org/article/ccd395b1712a4aac885b8c640c162469
UNSTRUCTURED Digital therapeutics (DTx) are software-based products that prevent, manage, or treat a medical condition, and are delivered through a smartphone app, web application or wearable. Clinical trials assessing DTx pose challenges, foremost a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27d369856f3e346138c1a06a1c3b0540
https://doi.org/10.2196/preprints.44764
https://doi.org/10.2196/preprints.44764
Autor:
Jacob T. Cain, Federica Rinaldi, Christopher Pierson, Cassandra N. Dennys-Rivers, Shibi Likhite, Katherine A. White, Stella Y. Lee, Sarah Corcoran, Stephanie M. Hughes, Derek J. Timm, Pablo R Morales, Samantha Davis, Jill M. Weimer, Tyler B. Johnson, Kathrin Meyer, Brian K. Kaspar, Dario Motti
Publikováno v:
Molecular Therapy
CLN6-Batten disease, a form of neuronal ceroid lipofuscinosis is a rare lysosomal storage disorder presenting with gradual declines in motor, visual, and cognitive abilities and early death by 12–15 years of age. We developed a self-complementary a
Innovating Health Against Future Pandemics covers the key aspects which drive heterogeneity in an individual's response to COVID-19, including age, sex, genetic makeup, immune responses, comorbidities, and viral strains/loads. This book also reviews
Autor:
Jessica K. Lerch, Dario Motti, Matt C. Danzi, Jared H. Gans, Tatiana I. Slepak, John L. Bixby, Vance Lemmon, Frank Kuo
Publikováno v:
FEBS Letters. 591:2091-2105
Peripheral neurons regenerate their axons after injury. Transcriptional regulation by microRNAs (miRNAs) is one possible mechanism controlling regeneration. We profiled miRNA expression in mouse dorsal root ganglion (DRG) neurons after a sciatic nerv
Autor:
Do-Hun Lee, Kara L. Spiller, Cynthia Soderblom, Vance Lemmon, Yunjiao Zhu, Kirill A. Lyapichev, John R. Bethea, Y. Zhang, J. Zha, Nicole M. Ferraro, Jae K. Lee, Stephanie L. Yahn, Dario Motti
Publikováno v:
The Journal of Neuroscience. 37:2362-2376
Although infiltrating macrophages influence many pathological processes after spinal cord injury (SCI), the intrinsic molecular mechanisms that regulate their function are poorly understood. A major hurdle has been dissecting macrophage-specific func
Autor:
Dario Motti, Roberta Brambilla, Pernille M. Madsen, John R. Bethea, Shaffiat Karmally, Kate Lykke Lambertsen, David E. Szymkowski
Publikováno v:
Madsen, P M, Motti, D, Karmally, S, Szymkoski, D E, Lambertsen, K L, Bethea, J R & Brambilla, R 2016, ' Oligodendroglial TNFR2 mediates membrane TNF-dependent repair in experimental autoimmune encephalomyelitis by promoting oligodendrocyte differentiation and remyelination ', The Journal of Neuroscience, vol. 36, no. 18, pp. 5128-5143 . https://doi.org/10.1523/JNEUROSCI.0211-16.2016
Tumor necrosis factor (TNF) is associated with the pathophysiology of various neurological disorders, including multiple sclerosis. It exists as a transmembrane form tmTNF, signaling via TNF receptor 2 (TNFR2) and TNFR1, and a soluble form, solTNF, s
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 1, Pp 144-149 (2016)
Neural Regeneration Research
Neural Regeneration Research
Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Administration of post-surgical analgesics is an important consideration for animal welfare, but the actions of the analgesic must not int