Separate and combined effects of DNMT and HDAC inhibitors in treating human multi-drug resistant osteosarcoma HosDXR150 cell line.

Autor: Enrico Capobianco, Antonio Mora, Dario La Sala, Annalisa Roberti, Nazar Zaki, Elarbi Badidi, Monia Taranta, Caterina Cinti

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95596 (2014)

Understanding the molecular mechanisms underlying multi-drug resistance (MDR) is one of the major challenges in current cancer research. A phenomenon which is common to both intrinsic and acquired resistance, is the aberrant alteration of gene expres

Externí odkaz: https://doaj.org/article/84351f9cd5a14e0cadcf2ba8d4133153

Pathway landscape and regulatory networks of epigenetically modified Breast Cancer genes

Autor: Mariama El Baroudi, Dario La Sala, Caterina Cinti, Enrico Capobianco

Epigenetic changes are a key regulator of gene expression in different cancer histotypes. After investigating the differentially expressed genes upon treatment with a demethylating agent, e.g. DAC, we performed pathways enrichment analysis and invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::ecba75a3bf7ecb924deee673fccc24ac
http://www.cnr.it/prodotto/i/279554

Activated Akt as an indicator of prognosis in gastric cancer

Autor: Carla Vindigni, Dario La Sala, Daniele Marrelli, Piero Tosi, Maria Carmela Epistolato, Caterina Cinti, Alessandra Zamparelli, Gabriele Cevenini

Publikováno v: Virchows Archiv : an international journal of pathology. 453(5)

The immunohistochemical expression of phosphorylated (activated) Akt (pAkt) in 50 advanced gastric carcinomas has been analyzed and the results correlated with age, sex, location in the stomach, histotype, stage, survival, mitotic and apoptotic index

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369ace407dad4466c9aaf2400ac70a8d
https://pubmed.ncbi.nlm.nih.gov/18841391

Combined Fluorescence In Situ Hybridization and PRINS for the Analysis of the Dystrophin Gene

Autor: Dario La Sala, Caterina Cinti, Liborio Stuppia

Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy are caused in most cases by deletions of the DMD gene. These rearrangements are detectable in affected boys and men by a simple multiplex polymerase chain reaction approach. However, thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f21edb072e094c21a27f2f86616e3b5
https://doi.org/10.1385/1-59745-068-5:115

Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: Implications for pathogenesis and therapeutic approach

Autor: Mina Massaro-Giordano, Carmela Trimarchi, Antonio Giordano, Caterina Cinti, Marcella Macaluso, Aldo Caporossi, Dario La Sala, Alfredo Ciccodicola, Stefano Lazzi, Gian Marco Tosi

Publikováno v: Oncogene (Basingstoke) 24 (2005): 5827–5836. doi:10.1038/sj.onc.1208630
info:cnr-pdr/source/autori:Tosi G.M.; Trimarchi C.; Macaluso M.; La Sala D.; Ciccodicola A.; Lazzi S.; Masssaro M.; Giordano M.; Caporossi A.; Giordano A.; Citti C./titolo:Genetic and epigenetic alterations of RB2%2FP130 tumor suppressor gene in human sporadic retinoplastoma: implications for pathogenesis and therapeutic approach/doi:10.1038%2Fsj.onc.1208630/rivista:Oncogene (Basingstoke)/anno:2005/pagina_da:5827/pagina_a:5836/intervallo_pagine:5827–5836/volume:24

Human retinoblastoma occurs in two forms (familial and sporadic) both due to biallelic mutation of the RB1/p105 gene even if its loss is insufficient for malignancy. We have recently reported that loss of expression of the retinoblastoma-related prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a7d6cacc3bf61c7621c89891e36040
http://hdl.handle.net/10807/125486