Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dario Giacomoni"'
Autor:
Dario Giacomoni
Publikováno v:
Journal of the History of Biology. 26:89-107
Besides its use in basic research, the DNA:RNA hybridization technique has helped the development of genetic engineering: it is instrumental in the isolation of specific genes that can be inserted into foreign cells, thus modifying their genetic info
Publikováno v:
Tumor Biology. 11:39-50
The human melanoma cell lines M21 and MSM-M2 are shown to produce two similar competitive inhibitors of trypsin, a serine proteinase. These proteinase inhibitors inhibited the serine proteinases trypsin and kallikrein with similar efficiency but did
Autor:
Fairouz Zoubir, Jan Szmeja, Robert A. Skilton, T. Bamett, Masaaki Adachi, Sheldon Dray, Dario Giacomoni, Jan Zeromski, Martin Gore, Kohzoh Imai, Sten Hammarström, Patricia M. Wilson, Jeffrey Mcllhinney, Akira Yachi, Teruaki Sekine, Helena M. Earl, Jan Sikora, A.M. Neville, Wolfgang Zimmermann, Satoshi Tsukikawa, Feridoon Najmabadi, Barry A. Gusterson, Anders Hedin, John F. Thompson, Charles Coombes, Atsushi Umemoto
Publikováno v:
Tumor Biology. 11:64-112
Publikováno v:
Medical oncology and tumor pharmacotherapy. 7(4)
The concentrated supernatants of nine human melanoma cell line cultures were analyzed for the presence of factors that inhibit in vitro immunological reactions. All cell lines secreted a factor that inhibited LPS-induced proliferation of murine B cel
Publikováno v:
Archives of Biochemistry and Biophysics. 201:392-402
The effect of various parameters on the liposome-mediated insertion of RNA into eucaryotic cells in vitro has been studied. Maximization of the insertion of liposome-encapsulated RNA into cells was approached at three levels: (1) alteration of liposo
Publikováno v:
Experimental Cell Research. 149:177-187
DNA molecules sequestered within negatively charged liposomes became nuclei-associated following interaction between isolated mouse plasmacytoma nuclei and liposomes. Few if any liposomes appeared to adhere to washed nuclei following their interactio
Publikováno v:
Immunological Communications. 2:129-139
RNA extracted from several plasmacytomas of BALB/c mice was previously shown in in vitro and in vivo experiments to induce the synthesis of receptors on B cells with The immunochemical characteristics of the respective plasmacytoma globulin. These fi
Autor:
Dario Giacomoni, David Finkel
Publikováno v:
Journal of Molecular Biology. 70:725-728
By the use of DNA-RNA hybridization it has been possible to show that ribosomal RNA cistrons of the cell line Pt-K1 of Potorous tridactylis duplicate late in the DNA duplication phase of the cell cycle (S-phase).
Publikováno v:
Biochemical and biophysical research communications. 76(3)
By utilizing an ether infusion technique with lecithin, cholesterol, and dicetylphosphate, giant liposomes have been produced with diameters ranging from 0.5 to 2.0 microns. These liposomes have been used to sequester 4S, 16S, and 23S E. coli [3H]RNA
Publikováno v:
Nature. 274(5674)
THE ability to insert messenger RNA selectively into large numbers of differentiated eukaryotic cells and thereby alter the expression of the eukaryotic genome would provide a new and direct approach to the study of the molecular mechanisms involved