Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Dario De Cesare"'
1
Akademický článek
Three-dimensional environment sensitizes pancreatic cancer cells to the anti-proliferative effect of budesonide by reprogramming energy metabolism
Autor: Eduardo Ibello, Federica Saracino, Donatella Delle Cave, Silvia Buonaiuto, Filomena Amoroso, Gennaro Andolfi, Marco Corona, Ombretta Guardiola, Vincenza Colonna, Bruno Sainz Jr, Lucia Altucci, Dario De Cesare, Gilda Cobellis, Enza Lonardo, Eduardo Jorge Patriarca, Cristina D’Aniello, Gabriella Minchiotti
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer with an aggressive metastatic phenotype and very poor clinical prognosis. Interestingly, a lower occurrence of PDAC has been described in individuals with severe an
Externí odkaz: https://doaj.org/article/b556c8edf2144cd3bd73b86564712a67
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2
Akademický článek
Budesonide Analogues Preserve Stem Cell Pluripotency and Delay 3D Gastruloid Development
Autor: Filomena Amoroso, Eduardo Ibello, Federica Saracino, Federica Cermola, Giovanna Ponticelli, Enrica Scalera, Francesca Ricci, Gino Villetti, Gilda Cobellis, Gabriella Minchiotti, Eduardo Jorge Patriarca, Dario De Cesare, Cristina D’Aniello
Publikováno v: Pharmaceutics, Vol 15, Iss 7, p 1897 (2023)
Small molecules that can modulate or stabilize cell–cell interactions are valuable tools for investigating the impact of collective cell behavior on various biological processes such as development/morphogenesis, tissue regeneration and cancer prog
Externí odkaz: https://doaj.org/article/2f2a501481174f1b98902d8d9fa73017
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3
Akademický článek
The Multifaceted Roles of Proline in Cell Behavior
Autor: Eduardo J. Patriarca, Federica Cermola, Cristina D’Aniello, Annalisa Fico, Ombretta Guardiola, Dario De Cesare, Gabriella Minchiotti
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino acid is: (i) A main precursor of extracellular collagens (the most abundant human proteins), antimicrobial peptides (involved in innate immunity), salivar
Externí odkaz: https://doaj.org/article/c9997dc73f754a6c8ef427970c2a7de1
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4
Akademický článek
Capturing Transitional Pluripotency through Proline Metabolism
Autor: Gabriella Minchiotti, Cristina D’Aniello, Annalisa Fico, Dario De Cesare, Eduardo Jorge Patriarca
Publikováno v: Cells, Vol 11, Iss 14, p 2125 (2022)
In this paper, we summarize the current knowledge of the role of proline metabolism in the control of the identity of Embryonic Stem Cells (ESCs). An imbalance in proline metabolism shifts mouse ESCs toward a stable naïve-to-primed intermediate stat
Externí odkaz: https://doaj.org/article/0b7957d13bb44caa831de89ca5860e36
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7
Gastruloid Development Competence Discriminates Different States of Pluripotency
Autor: Eduardo J. Patriarca, Rosarita Tatè, Gabriella Minchiotti, Dario De Cesare, Federica Cermola, Alfonso Martinez-Arias, Cristina D'Aniello
Publikováno v: Stem Cell Reports
Stem Cell Reports 16 (2021): 354–369. doi:10.1016/j.stemcr.2020.12.013
info:cnr-pdr/source/autori:Cermola, Federica; D'Aniello, Cristina; Tatè, Rosarita; De Cesare, Dario; Martinez-Arias, Alfonso; Minchiotti, Gabriella; Patriarca, Eduardo Jorge/titolo:Gastruloid Development Competence Discriminates Different States of Pluripotency/doi:10.1016%2Fj.stemcr.2020.12.013/rivista:Stem Cell Reports/anno:2021/pagina_da:354/pagina_a:369/intervallo_pagine:354–369/volume:16
Summary Floating spheroidal aggregates of mouse embryonic stem cells can develop into polarized/elongated organoids, namely gastruloids. We set up a high-performing assay to measure gastruloid formation efficiency (GFE), and found that GFE decreases
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9234debfd72d1995051ffd5e0eae2d6b
https://doi.org/10.1016/j.stemcr.2020.12.013
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8
Stabilization of cell-cell adhesions prevents symmetry breaking and locks in pluripotency in 3D gastruloids
Autor: Federica Cermola, Filomena Amoroso, Federica Saracino, Eduardo Ibello, Dario De Cesare, Annalisa Fico, Gilda Cobellis, Enrica Scalera, Costanza Casiraghi, Cristina D’Aniello, Eduardo Jorge Patriarca, Gabriella Minchiotti
3D embryonic stem cell (ESC) aggregates self-organize into embryo-like structures named gastruloids that recapitulate the axial organization of post-implantation embryos. Crucial in this process is the symmetry-breaking event that leads to the emerge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244083ee04b49f118b2e38d6414eb4a4
https://hdl.handle.net/11591/482834
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9
The Multifaceted Roles of Proline in Cell Behavior
Autor: Annalisa Fico, Dario De Cesare, Federica Cermola, Eduardo J. Patriarca, Gabriella Minchiotti, Ombretta Guardiola, Cristina D'Aniello
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology 9 (2021). doi:10.3389/fcell.2021.728576
info:cnr-pdr/source/autori:Patriarca E.J.; Cermola F.; D'Aniello C.; Fico A.; Guardiola O.; De Cesare D.; Minchiotti G./titolo:The Multifaceted Roles of Proline in Cell Behavior/doi:10.3389%2Ffcell.2021.728576/rivista:Frontiers in Cell and Developmental Biology/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Frontiers in Cell and Developmental Biology
Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino acid is: (i) A main precursor of extracellular collagens (the most abundant human proteins), antimicrobial peptides (involved in innate immunity), salivar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6bce68264226bc446661a85694d05b
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10
Gastruloid development competence discriminates different states of pluripotency between naïve and primed
Autor: Eduardo J. Patriarca, Alfonso Martinez-Arias, Rosarita Tatè, Dario De Cesare, Cristina D'Aniello, Gabriella Minchiotti, Federica Cermola
Publikováno v: bioRxiv the preprint server for biology (2019). doi:10.1101/664920
info:cnr-pdr/source/autori:Federica Cermola, Cristina D'Aniello, Rosarita Tatè, Dario De Cesare, Alfonso Martinez-Arias, Gabriella Minchiotti, Eduardo Jorge Patriarca/titolo:Gastruloid development competence discriminates different states of pluripotency between naïve and primed/doi:10.1101%2F664920/rivista:bioRxiv the preprint server for biology/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
Floating spheroidal aggregates (aggregomes) of mouse embryonic stem cells (mESCs) can develop into polarized/elongated organoids, namely gastruloids. Here we report a high-performing assay to measure gastruloids formation efficiency (GFE), i.e. the f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fecc44ee57fa7cb5d913855ab2ea16
http://www.cnr.it/prodotto/i/409151
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