Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dario A. Dilernia"'
Autor:
Kelsie Brooks, Bradley R Jones, Dario A Dilernia, Daniel J Wilkins, Daniel T Claiborne, Samantha McInally, Jill Gilmour, William Kilembe, Jeffrey B Joy, Susan A Allen, Zabrina L Brumme, Eric Hunter
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008378 (2020)
The HIV-1 reservoir consists of latently infected cells that persist despite antiretroviral therapy (ART). Elucidating the proviral genetic composition of the reservoir, particularly in the context of pre-therapy viral diversity, is therefore importa
Externí odkaz:
https://doaj.org/article/13bf90a11ad542a4b717846ef1e5870e
Autor:
Kai Qin, Sushma Boppana, Victor Y Du, Jonathan M Carlson, Ling Yue, Dario A Dilernia, Eric Hunter, Robbie B Mailliard, Simon A Mallal, Anju Bansal, Paul A Goepfert
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007970 (2019)
HIV-1 frequently escapes from CD8 T cell responses via HLA-I restricted adaptation, leading to the accumulation of adapted epitopes (AE). We previously demonstrated that AE compromise CD8 T cell responses during acute infection and are associated wit
Externí odkaz:
https://doaj.org/article/3696d0d7ba3d4746ac4e5e12f2e06f3d
Publikováno v:
AIDS. 34:2201-2210
Objective Short-read next-generation sequencing (NGS) has been implemented to study the resistance profile of HIV as it provides a higher sensitivity than Sanger sequencing. However, short-reads only generates a consensus view of the viral population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ccbcba1f59f11efaf974a5ab0112498
https://doi.org/10.1097/qad.0000000000002697
https://doi.org/10.1097/qad.0000000000002697
Autor:
Dario A. Dilernia, Kimberley Herard, Ling Yue, Gisele Umviligihozo, Rui Xu, Qianhong Qin, Susan Allen, Etienne Karita, Jean Bizimana, Jonathan Hare, Emmanuel Nyirimihigo Gisa, Erick M. O. Muok, Paul Farmer, Heeyah Song, Eric Hunter, Jill Gilmour
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
Most studies of HIV-1 transmission have focused on subtypes B and C. In this study, we determined the genomic sequences of the transmitted founder (TF) viruses from acutely infected individuals enrolled between 2005 and 2011 into IAVI protocol C in R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acfbadd77d2a3a2fdf59da8250652d9
http://europepmc.org/articles/PMC8529237
http://europepmc.org/articles/PMC8529237
Autor:
Martin J Deymier, Zachary Ende, Angharad E Fenton-May, Dario A Dilernia, William Kilembe, Susan A Allen, Persephone Borrow, Eric Hunter
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005154 (2015)
Heterosexual transmission of HIV-1 is characterized by a genetic bottleneck that selects a single viral variant, the transmitted/founder (TF), during most transmission events. To assess viral characteristics influencing HIV-1 transmission, we sequenc
Externí odkaz:
https://doaj.org/article/577a197d3f7f485b9782389b62cbd026
Autor:
Gisele Umviligihozo, Ed McGowan, Jonathan Hare, David A. Morrison, Andrew Fiore-Gartland, Daniela C. Monaco, Jama Dalel, Dario A. Dilernia, Eric Hunter, Morten Nielsen, Gladys Macharia, Helen Coutinho, Claire Streatfield, Ling Yue, Sheila Balinda, Erick M. O. Muok, Jill Gilmour, Rachel Rosenthal, Anne Kapaata
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Predictive models are becoming more and more commonplace as tools for candidate antigen discovery to meet the challenges of enabling epitope mapping of cohorts with diverse HLA properties. Here we build on the concept of using two key parameters, div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0f0b14771c235a5bdf65b5899fb9b8
https://doi.org/10.3389/fimmu.2021.609884
https://doi.org/10.3389/fimmu.2021.609884
Autor:
Ling Yue, Dario A. Dilernia, Eric Hunter, Sheila N. Balinda, Jonathan Hare, Kimberly Herard, Kato Laban, Anne Kapaata, Eugene Ruzagira, Jesus F. Salazar-Gonzalez, Matthew Cotten, Rui Xu, Jill Gilmour, Freddie Mukasa, Maria G. Salazar, Anatoli Kamali, Pontiano Kaleebu, Kelsie Brooks
Publikováno v:
Viruses
Volume 13
Issue 2
Viruses, Vol 13, Iss 171, p 171 (2021)
Volume 13
Issue 2
Viruses, Vol 13, Iss 171, p 171 (2021)
The ability to efficiently establish a new infection is a critical property for human immunodeficiency virus type 1 (HIV-1). Although the envelope protein of the virus plays an essential role in receptor binding and internalization of the infecting v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f1e517da66726e03c4f598ffefc960
http://europepmc.org/articles/PMC7912664
http://europepmc.org/articles/PMC7912664
Autor:
Dario A Dilernia, Daniela C Monaco, Carina Cesar, Alejandro J Krolewiecki, Samuel R Friedman, Pedro Cahn, Horacio Salomon
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53193 (2013)
In HIV infection, initiation of treatment is associated with improved clinical outcom and reduced rate of sexual transmission. However, difficulty in detecting infection in early stages impairs those benefits. We determined the minimum testing rate t
Externí odkaz:
https://doaj.org/article/c591bcac66cb4af9836161ed6402201c
Autor:
Dario Alberto Dilernia, Leandro Jones, Sabrina Rodriguez, Gabriela Turk, Andrea E. Rubio, Sandra Pampuro, Manuel Gomez-Carrillo, Christian T. Bautista, Gabriel Deluchi, Jorge Benetucci, María Beatriz Lasala, Leonardo Lourtau, Marcelo Horacio Losso, Héctor Perez, Pedro Cahn, Horacio Salomón
Publikováno v:
PLoS ONE, Vol 3, Iss 11 (2008)
Externí odkaz:
https://doaj.org/article/21ff4e18474f48bc9593cc22b21f5763
Autor:
Dario Alberto Dilernia, Leandro Jones, Sabrina Rodriguez, Gabriela Turk, Andrea E Rubio, Sandra Pampuro, Manuel Gomez-Carrillo, Christian T Bautista, Gabriel Deluchi, Jorge Benetucci, María Beatriz Lasala, Leonardo Lourtau, Marcelo Horacio Losso, Héctor Perez, Pedro Cahn, Horacio Salomón
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3429 (2008)
BACKGROUND: Cytotoxic T-Lymphocyte (CTL) response drives the evolution of HIV-1 at a host-level by selecting HLA-restricted escape mutations. Dissecting the dynamics of these escape mutations at a population-level would help to understand how HLA-med
Externí odkaz:
https://doaj.org/article/cc75118f559744339f20022eb86b387f