Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Dario, Rusciano"'
Autor:
Dario Rusciano, Paola Bagnoli
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 9, p 319 (2024)
Oxidative stress, caused by the formation of free radicals, such as reactive oxygen species (ROS), leads to cell and tissue degradation, contributing to various diseases and aging. While oxygen is essential for aerobic organisms, it inevitably causes
Externí odkaz:
https://doaj.org/article/f9bda02e03fa40218ea235c9217a1176
Autor:
Caterina Gagliano, Maria Letizia Salvetat, Mutali Musa, Fabiana D'Esposito, Dario Rusciano, Antonino Maniaci, Francesco Pellegrini, Giuseppe Scibilia, Marco Zeppieri
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 8, p 310 (2024)
This review explores the connection between the ocular surface microbiome and glaucoma, highlighting its impact on disease progression. Beginning with an overview of global glaucoma significance, it emphasizes the importance of understanding the cell
Externí odkaz:
https://doaj.org/article/a6564b6fbaf94f0694f4c130c3b7c935
Autor:
Dario Rusciano
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 623 (2024)
Gabapentin (GBP) was originally developed as a potential agonist for Gamma-Amino-Butyric-Acid (GABA) receptors, aiming to inhibit the activation of pain-signaling neurons. Contrary to initial expectations, it does not bind to GABA receptors. Instead,
Externí odkaz:
https://doaj.org/article/f0e6401ad3934091bbe9ee91ebceb73d
Autor:
Alberto Melecchi, Rosario Amato, Massimo Dal Monte, Dario Rusciano, Paola Bagnoli, Maurizio Cammalleri
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionMuch interest has been addressed to antioxidant dietary supplements that are known to lower the risk of developing glaucoma or delay its progression. Among them, niacin and citicoline protect retinal ganglion cells (RGCs) from degeneratio
Externí odkaz:
https://doaj.org/article/efe3fbfdd5f44d749632d04b2ca4c0f0
Autor:
Dario Rusciano, Cristina Russo
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 441 (2024)
Melatonin is a ubiquitous molecule found in living organisms, ranging from bacteria to plants and mammals. It possesses various properties, partly due to its robust antioxidant nature and partly owed to its specific interaction with melatonin recepto
Externí odkaz:
https://doaj.org/article/81f1dd3a46754dc798cacb11ae9114d7
Publikováno v:
Medicina, Vol 60, Iss 3, p 354 (2024)
Antioxidants, usually administered orally through the systemic route, are known to counteract the harmful effects of oxidative stress on retinal cells. The formulation of these antioxidants as eye drops might offer a new option in the treatment of ox
Externí odkaz:
https://doaj.org/article/936cfe8e78a14dde88539b18c9129452
Autor:
Alberto Melecchi, Rosario Amato, Dominga Lapi, Massimo Dal Monte, Dario Rusciano, Paola Bagnoli, Maurizio Cammalleri
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Age-related macular degeneration (AMD) is nowadays considered among the retinal diseases whose clinical management lacks established treatment approaches, mainly for its atrophic (dry) form. In this respect, the use of dietary patterns enriched in om
Externí odkaz:
https://doaj.org/article/c3a713847ad04710908355b50c959d80
Autor:
Dario Rusciano, Paola Bagnoli
Publikováno v:
Medicina, Vol 59, Iss 7, p 1334 (2023)
In this review, we aim to provide an overview of the recent findings about the treatment of neovascular retinal diseases. The use of conventional drugs and nutraceuticals endowed with antioxidant and anti-inflammatory properties that may support conv
Externí odkaz:
https://doaj.org/article/2cf0036c90ec4ae78ae6cc5b9550bca7
Autor:
Cristina Minnelli, Francesco Piva, Monia Cecati, Tatiana Armeni, Giovanna Mobbili, Roberta Galeazzi, Alberto Melecchi, Martina Cristaldi, Roberta Corsaro, Dario Rusciano
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 594 (2023)
Meldonium (MID) is a synthetic drug designed to decrease the availability of L-carnitine—a main player in mitochondrial energy generation—thus modulating the cell pathways of energy metabolism. Its clinical effects are mostly evident in blood ves
Externí odkaz:
https://doaj.org/article/193a1a8c9d274e9b8c5f36b20f3f0933
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/db9c176ad783498e9ad40eb43ea4814b