Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Dario, Didona"'
Autor:
Henriette Franz, Maitreyi Rathod, Aude Zimmermann, Chiara Stüdle, Vivien Beyersdorfer, Karen Leal-Fischer, Pauline Hanns, Tomás Cunha, Dario Didona, Michael Hertl, Marion Scheibe, Falk Butter, Enno Schmidt, Volker Spindler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cell-cell junctions, and specifically desmosomes, are crucial for robust intercellular adhesion. Desmosomal function is compromised in the autoimmune blistering skin disease pemphigus vulgaris. We combine whole-genome knockout screening and
Externí odkaz:
https://doaj.org/article/5299e4b0ab3a4e0d82122e76ecb37ed4
Autor:
Jona Schinner, Tomas Cunha, Johannes U. Mayer, Stefan Hörster, Peter Kind, Dario Didona, Corinna Keber, Michael Hertl, Thomas Worzfeld, Hazem A. Juratli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe here thought to dissect the inflammatory signature in lesions of three skin disorders, which show a common adaptive immune response against autoantigens of the skin but are characterized by diverging clinical phenotypes. Pemphigus vulg
Externí odkaz:
https://doaj.org/article/37d5ee7a440a444bbade011147d5dd2b
Autor:
Roberto Maglie, Farzan Solimani, Dario Didona, Carlo Pipitò, Emiliano Antiga, Giovanni Di Zenzo
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also referred to as BP180, is the main pathogenic event of BP, leading to produc
Externí odkaz:
https://doaj.org/article/a87b26b084b84f62b6bd8c5778e78746
Autor:
Dario Didona, Antonio Manuel Sequeira Santos, Tomas Cunha, Julia Hinterseher, Jacqueline Kussini, Michael Hertl
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Behçet’s disease (BD) is a systemic inflammatory disease of unknown etiology. BD is characterized by relapsing oral and genital ulcers, several different cutaneous features, relapsing bilateral uveitis, and involvement of internal organs, showing
Externí odkaz:
https://doaj.org/article/c67c566cbc1d43bf8e59f9a7d064c1f5
Autor:
Dario Didona, Raffaele Dante Caposiena Caro, Antonio Manuel Sequeira Santos, Farzan Solimani, Michael Hertl
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa. Several clinical subtypes of OLP have been reported, including the reticular and erosive one. On the one hand, reticular OLP is usually asymptomatic and is characterized b
Externí odkaz:
https://doaj.org/article/b13bce27ac8547d09ab2be0517edd2cb
Autor:
Dario Didona, Michael Hertl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Oral lichen planus (OLP) is an inflammatory disease of the oral mucosa. Clinically, two main subsets are described, namely non-erosive and erosive OLP. While non-erosive OLP is usually responsive to local therapies, erosive OLP is often refractory al
Externí odkaz:
https://doaj.org/article/17577a11bf764e8eba24c2566db0158f
Autor:
Alexandra Polakova, Leonie Kauter, Adina Ismagambetova, Dario Didona, Farzan Solimani, Kamran Ghoreschi, Michael Hertl, Christian Möbs, Christoph Hudemann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Analysis of T lymphocyte proliferation and activation after antigenic or mitogenic stimulation is a vital parameter used in the diagnosis of various immuno-deficiencies and during the monitoring of treatment responses. Most applied techniques are bas
Externí odkaz:
https://doaj.org/article/d9709003ca344348a6e3996d8dd71d55
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/45b96e567f734305b612313c5689358b
Autor:
Hideyuki Ujiie, David Rosmarin, Michael P. Schön, Sonja Ständer, Katharina Boch, Martin Metz, Marcus Maurer, Diamant Thaci, Enno Schmidt, Connor Cole, Kyle T. Amber, Dario Didona, Michael Hertl, Andreas Recke, Hanna Graßhoff, Alexander Hackel, Anja Schumann, Gabriela Riemekasten, Katja Bieber, Gant Sprow, Joshua Dan, Detlef Zillikens, Tanya Sezin, Angela M. Christiano, Kerstin Wolk, Robert Sabat, Khalaf Kridin, Victoria P. Werth, Ralf J. Ludwig
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
An estimated 20–25% of the population is affected by chronic, non-communicable inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most frequent chronic inflammatory skin diseases are atopic dermatitis, psoriasis, urtic
Externí odkaz:
https://doaj.org/article/b4d49925740d40d997ea17caa001b46a
Autor:
Daniela Kugelmann, Maresa Anders, Anna M. Sigmund, Desalegn T. Egu, Ramona A. Eichkorn, Amir S. Yazdi, Miklós Sárdy, Michael Hertl, Dario Didona, Takashi Hashimoto, Jens Waschke
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The severe autoimmune blistering disease Pemphigus vulgaris (PV) is mainly caused by autoantibodies (IgG) against desmoglein (Dsg) 3 and Dsg1. The mechanisms leading to the development of blisters are not fully understood, but intracellular signaling
Externí odkaz:
https://doaj.org/article/bf9ecf11ae6e48e982490804fb4a2c1c