Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dario, De Vecchis"'
Autor:
Sille Remm, Dario De Vecchis, Jendrik Schöppe, Cedric A. J. Hutter, Imre Gonda, Michael Hohl, Simon Newstead, Lars V. Schäfer, Markus A. Seeger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mycobacterium tuberculosis is protected from antibiotic therapy by a multi-layered hydrophobic cell envelope. Major facilitator superfamily (MFS) transporter Rv1410 and the periplasmic lipoprotein LprG are involved in transport of triacylgly
Externí odkaz:
https://doaj.org/article/1960b492e8a54571b9bda14e84f5dd05
Autor:
Laura C. Paweletz, Simon L. Holtbrügge, Malina Löb, Dario De Vecchis, Lars V. Schäfer, Thomas Günther Pomorski, Bo Højen Justesen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13106 (2023)
The activity of membrane proteins depends strongly on the surrounding lipid environment. Here, we characterize the lipid stimulation of the plant plasma membrane H+-ATPase Arabidopsis thaliana H+-ATPase isoform 2 (AHA2) upon purification and reconsti
Externí odkaz:
https://doaj.org/article/a01b587d14454452968f2c4d4108c91c
Autor:
Jian Shi, Adam J. Hyman, Dario De Vecchis, Jiehan Chong, Laeticia Lichtenstein, T. Simon Futers, Myriam Rouahi, Anne Negre Salvayre, Nathalie Auge, Antreas C. Kalli, David J. Beech
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108225- (2020)
Summary: Endogenous PIEZO1 channels of native endothelium lack the hallmark inactivation often seen when these channels are overexpressed in cell lines. Because prior work showed that the force of shear stress activates sphingomyelinase in endotheliu
Externí odkaz:
https://doaj.org/article/f6b344136b464cb480bd078a6a9a4088
Publikováno v:
Data in Brief, Vol 26, Iss , Pp - (2019)
In this work we present a novel set of possible auto-oligomerisation states of yeast protein Fzo1 in the context of membrane docking. The dataset reports atomistic models and trajectories derived from a molecular dynamics study of the yeast mitofusin
Externí odkaz:
https://doaj.org/article/7deee50ec6254ca5af157818b51d2e23
Autor:
Laura, Galazzo, Gianmarco, Meier, Dovile, Januliene, Kristian, Parey, Dario, De Vecchis, Bianca, Striednig, Hubert, Hilbi, Lars V, Schäfer, Ilya, Kuprov, Arne, Moeller, Enrica, Bordignon, Markus A, Seeger
Publikováno v:
Science advances. 8(41)
Membrane proteins are currently investigated after detergent extraction from native cellular membranes and reconstitution into artificial liposomes or nanodiscs, thereby removing them from their physiological environment. However, to truly understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f77de5427ef9758024a169327c2c10af
https://pubmed.ncbi.nlm.nih.gov/36223470
https://pubmed.ncbi.nlm.nih.gov/36223470
Autor:
Melanie J. Ludlow, Dario De Vecchis, Adam J. Hyman, Jiehan Chong, Oleksandr V. Povstyan, David J. Beech, Antreas C. Kalli, Jian Shi
Publikováno v:
Biophysical Journal. 120:1343-1356
Piezo1 forms a mechanically activated calcium-permeable nonselective cation channel that is functionally important in many cell types. Structural data exist for C-terminal regions, but we lack information about N-terminal regions and how the entire c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e8a3d159c7241fec33ea3343d75721
https://doi.org/10.1016/j.bpj.2021.02.003
https://doi.org/10.1016/j.bpj.2021.02.003
Autor:
Gregory Parsonage, Neil E. Humphreys, Oleksandr V. Povstyan, Dario De Vecchis, Antony Adamson, Fraser L. Macrae, T. Simon Futers, Melanie J. Ludlow, Laeticia Lichtenstein, David J. Beech, Antreas C. Kalli, Elizabeth L. Evans
Publikováno v:
Blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82cbc0518e14824790886cfd8e76b93
https://doi.org/10.1182/blood.2019004174
https://doi.org/10.1182/blood.2019004174
Piezo1 is a mechanosensitive channel involved in many cellular functions and responsible for sensing shear stress and pressure forces in cells. Piezo1 has a unique trilobed topology with a curved membrane region in the closed state. It has been sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac790521508f7acfba27fa728d2b16e5
https://eprints.whiterose.ac.uk/170716/12/mmc4.pdf
https://eprints.whiterose.ac.uk/170716/12/mmc4.pdf
Autor:
Laeticia Lichtenstein, Jian Shi, Myriam Rouahi, Nathalie Augé, Jiehan Chong, Adam J. Hyman, David J. Beech, Dario De Vecchis, T. Simon Futers, Antreas C. Kalli, Anne Negre Salvayre
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108225-(2020)
Cell Reports
Cell Reports
Summary Endogenous PIEZO1 channels of native endothelium lack the hallmark inactivation often seen when these channels are overexpressed in cell lines. Because prior work showed that the force of shear stress activates sphingomyelinase in endothelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f617e95adfb6511becfddf686dd716
https://eprints.whiterose.ac.uk/165506/15/1-s2.0-S2211124720312146-main.pdf
https://eprints.whiterose.ac.uk/165506/15/1-s2.0-S2211124720312146-main.pdf
Autor:
Piruthivi Sukumar, Dario De Vecchis, Antreas C. Kalli, Chew Weng Cheng, Melanie J. Ludlow, Vijayalakshmi Deivasikamani, David J. Beech
Fatality from coronavirus disease 19 (COVID-19) is a major problem globally and so identification of its underlying molecular mechanisms would be helpful. The combination of COVID-19 clinical data and genome sequence information is providing a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6f9b5f8b002c66b8c571477b03b286