Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Darina Slameňová"'
Publikováno v:
Food Chemistry. 129:64-70
Rosemary oil (RO) is popular in the Mediterranean region as a culinary additive which has the ability to protect delicate organs such as liver, brain and heart. We examined the effect of RO consumption on resistance of rat testicular cells (TCs) agai
Publikováno v:
Food Chemistry. 123:151-156
The aim of this paper was to evaluate the potential DNA-protective effects of rosemary essential oil-supplementation on rat hepatocytes damaged with three different genotoxins attacking DNA by oxidative stress. Hydrogen peroxide (H2O2) reacts by the
Publikováno v:
Toxicology in Vitro. 24:1986-1992
A large number of functional foods, including those that contain β- d -glucans, have been shown to prevent human DNA against genotoxic effects and associated development of cancer and other chronic diseases. In this paper, carboxymethyl chitin-gluca
Publikováno v:
Holzforschung. 60:166-170
The antioxidative behavior of various lignin preparations derived from chemical wood treatment for paper production was examined. All lignin samples exhibited higher antioxidant activity than Trolox. The protective effect of lignin antioxidants again
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 593:97-107
This study tried to clarify the question if nuclear genotoxicity played a role in 3′-azido-3′-deoxythymidine (AZT) toxicity. We investigated cytotoxic and DNA-damaging effects of AZT on human hepatoma HepG2 and human colonic CaCo-2 cells as well
Autor:
Alena Gábelová, Zuzana Valovičová, Radim J. Sram, Blanka Binkova, Peter B. Farmer, Darina Slameňová, Eva Horváthová
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 563:49-59
The genotoxic potential of extractable organic matter (EOM) associated with the respirable particulate matter (PM10 microm) of atmospheric pollution has been determined in three European cities--Prague (Czech Republic, two monitoring sites, Libus and
Autor:
Darina Slameňová, Soňa Robichová
Publikováno v:
Cancer Letters. 182:11-18
Since N-nitroso compounds as strong carcinogens are closely related to food and nutrition, the cytotoxic effects of N-nitrosomorpholine (NMOR) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and their reduction by vitamins C and E were investigated i
Publikováno v:
Cancer Letters. 177:145-153
In this study possible protective effects of rosemary against oxidative DNA damage induced by H 2 O 2 - and visible light-excited Methylene Blue in colon cancer cells CaCo-2 and hamster lung cells V79 were investigated. The level of DNA damage (DNA s
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 497:63-70
Pentoxifylline (PTX) is a methylxanthine widely used in clinical practice. The mechanism of PTX effects on cellular and molecular level have not been fully explained yet. The present study was carried out to investigate the cytogenetic effect of this
Autor:
Alena Gábelová, Tapan Kumar Mandal, Lucia Hlinčı́ková, Eva Horváthová, Andrew Collins, Darina Slameňová
Publikováno v:
Mutation Research/DNA Repair. 409:163-171
After treatment with N-methyl-N′-nitro-N-nitrosoguanidine (MNNG), methyl methanesulfonate (MMS) and hydrogen peroxide, the level of alkali-labile sites and single-strand breaks (ssb) in DNA was investigated, using the comet assay. The ability of an