Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Darina Paprčková"'
Autor:
Andrea Ujevic, Daniela Knizkova, Alzbeta Synackova, Michaela Pribikova, Tijana Trivic, Anna Dalinskaya, Ales Drobek, Veronika Niederlova, Darina Paprckova, Roldan De Guia, Petr Kasparek, Jan Prochazka, Juraj Labaj, Olha Fedosieieva, Bernhard Florian Roeck, Ondrej Mihola, Zdenek Trachtulec, Radislav Sedlacek, Ondrej Stepanek, Peter Draber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The cytokine TNF can trigger highly proinflammatory RIPK1-dependent cell death. Here, we show that the two adapter proteins, TANK and AZI2, suppress TNF-induced cell death by regulating the activation of TBK1 kinase. Mice lacking either TANK
Externí odkaz:
https://doaj.org/article/9b7940ea388e4264884e77c454cce6f0
Autor:
Darina Paprckova, Veronika Niederlova, Alena Moudra, Ales Drobek, Michaela Pribikova, Sarka Janusova, Kilian Schober, Ales Neuwirth, Juraj Michalik, Martina Huranova, Veronika Horkova, Michaela Cesnekova, Michaela Simova, Jan Prochazka, Jana Balounova, Dirk H. Busch, Radislav Sedlacek, Martin Schwarzer, Ondrej Stepanek
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mature T cells are selected for recognizing self-antigens with low to intermediate affinity in the thymus. Recently, the relative differences in self-reactivity among individual T-cell clones were appreciated as important factors regulating their fat
Externí odkaz:
https://doaj.org/article/3d221b08845a4bd9b620763e054dec64
Autor:
Enrique Castano, Sukriye Yildirim, Veronika Fáberová, Alžběta Krausová, Lívia Uličná, Darina Paprčková, Martin Sztacho, Pavel Hozák
Publikováno v:
Cells, Vol 8, Iss 7, p 649 (2019)
The many functions of phosphoinositides in cytosolic signaling were extensively studied; however, their activities in the cell nucleus are much less clear. In this review, we summarize data about their nuclear localization and metabolism, and review
Externí odkaz:
https://doaj.org/article/0c81e53f09724015acc7e81838d05b4f
Autor:
Ondrej Stepanek, Darina Paprčková
Publikováno v:
The FEBS Journal. 288:1778-1788
It has been appreciated for more than three decades that the interactions between the T-cell antigen receptor and self-antigens are the major determinants of the cell fates of developing thymocytes and the establishment of central tolerance. However,
Autor:
Veronika Fáberová, Lívia Uličná, Enrique Castaño, Darina Paprčková, Martin Sztacho, Alžběta Krausová, Sukriye Yildirim, Pavel Hozák
Publikováno v:
Cells, Vol 8, Iss 7, p 649 (2019)
Cells
Cells
The many functions of phosphoinositides in cytosolic signaling were extensively studied; however, their activities in the cell nucleus are much less clear. In this review, we summarize data about their nuclear localization and metabolism, and review
Publikováno v:
Histochemistry and cell biology. 150(3)
Even though the majority of knowledge about phospholipids comes from their cytoplasmic functions, in the last decade, it has been shown that nuclear phospholipids and their building blocks, inositol phosphates, have many important roles in the cell n