Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Darina, Slamenova"'
Autor:
Eva Horváthová, Andrea Sevcovicova, Darina Slamenova, Barbara Kusznierewicz, Tomasz Chmiel, Katarína Kozics, Eliška Gálová, Martina Melušová
Publikováno v:
Neoplasma. 64(6)
Knowledge of biological properties of natural compounds allows to understand their therapeutic value, efficacy and security. We investigated: composition of Lavandula angustifolia (LA) and Rosmarinus officinalis (RO) extracts, their antioxidant capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef57c09d6abc53adef0cabdba99d69b
https://pubmed.ncbi.nlm.nih.gov/28895410
https://pubmed.ncbi.nlm.nih.gov/28895410
Publikováno v:
Neoplasma. 62(5)
We investigated activities of antioxidant enzymes (AEs), superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) in human HepG2 and hamster V79 cells treated with a scale of concentrations of hydrogen peroxide (H2O2), tert-butyl h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3395a81f997c7edc6b0aeb9702d52a47
https://pubmed.ncbi.nlm.nih.gov/26278149
https://pubmed.ncbi.nlm.nih.gov/26278149
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 600:131-137
Ursolic acid (UA) and oleanolic acid (OA) have similar chemical structures but differ in the position of one methyl group on the ring E. We investigated protective effects of these two triterpenoic acids against H(2)O(2)-induced DNA damage in leukemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15995cb1b07ff5d8ab9b5b8c36752268
https://doi.org/10.1016/j.mrfmmm.2006.03.008
https://doi.org/10.1016/j.mrfmmm.2006.03.008
Publikováno v:
Chemico-Biological Interactions. 148:163-171
N-nitrosomorpholine (NMOR) is a well-known hepatocarcinogen. Since this compound is representative of the group of indirect-acting N-nitrosamines, its metabolic activation should be essential. However, the mechanism of NMOR-induced carcinogenesis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9430b529c3e560257ba7e31bf66d6e7c
https://doi.org/10.1016/j.cbi.2004.06.002
https://doi.org/10.1016/j.cbi.2004.06.002
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 560:91-99
Introduction: N -Nitrosomorpholine (NMOR), present in the workplace of tyre chemical factories, is a known hepatocarcinogen. This compound belongs to the group of N -nitrosamines, which are indirect-acting and require metabolic activation. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113f5e6ca3203d702735889c8bf34af2
https://doi.org/10.1016/j.mrgentox.2004.01.011
https://doi.org/10.1016/j.mrgentox.2004.01.011
Autor:
Darina Slamenova, Juraj Labaj, Eva Horváthová, I. Masterova, Jana Jakubikova, Pavol Kubala, Ladislava Wsolova
Publikováno v:
Pharmacology and Toxicology. 94:282-290
Three diterpenoid quinones (royleanone – SAR 3, horminone – SAR 26, and acetyl horminone – SAR 43) isolated from the roots of Salvia officinalis L. were tested for their cytotoxic and DNA-damaging activity in human colon carcinoma cells Caco-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ec3c38046180b23541177ef2a26fcf
https://doi.org/10.1111/j.1742-7843.2004.pto940605.x
https://doi.org/10.1111/j.1742-7843.2004.pto940605.x
Autor:
Monika Lazarová, Darina Slamenova
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 557:167-175
Genotoxicity of complex mixtures of organic compounds adsorbed onto ambient air particles (extractable organic matter, EOM) collected in Teplice (Czech Republic) as well as genotoxicity of the indirectly acting carcinogens benzo[a]pyrene (B[a]P) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae125ff7e48ce1558439665bd81be20a
https://doi.org/10.1016/j.mrgentox.2003.10.011
https://doi.org/10.1016/j.mrgentox.2003.10.011
Autor:
Livia Krizkova, Peter Eckl, Nikolaus Bresgen, Darina Slamenova, Juraj Labaj, Grigorij Kogan, Jozef Šandula
Publikováno v:
Cancer Letters. 198:153-160
beta-Glucans belong to the class of substances known as biological response modifiers with a broad range of activity. We have investigated two types of glucans: (1--3)-beta-D glucan from the baker's yeast Saccharomyces cerevisiae and beta-glucan-chit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc870ac03ae882875a3ee177c2fa79ef
https://doi.org/10.1016/s0304-3835(03)00336-7
https://doi.org/10.1016/s0304-3835(03)00336-7
Autor:
K. Kleibl, Sona Robichová, Alena Gábelová, Eva Horváthová, Jana Jakubikova, Jan Sedlak, Darina Slamenova, L'Ubica Hrusovska
Publikováno v:
Environmental and Molecular Mutagenesis. 41:28-36
The antioxidant butylated hydroxyanisole (BHA) is a rodent carcinogen that also reduces the mutagenicity and carcinogenicity of other agents. In this study, we have evaluated possible mechanisms for the antimutagenicity of BHA by investigating its ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad607d77d796ef08c42100a85e666180
https://doi.org/10.1002/em.10127
https://doi.org/10.1002/em.10127
Publikováno v:
Alternatives to laboratory animals : ATLA. 27(3)
Apoptosis is a programmed form of cell death which occurs in response to specific stimuli. It is distinguished from necrotic or accidental cell death by unique events, including the degradation of chromatin and a loss of cellular volume. In contrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9faac8fc223954723f2c98be419324
https://pubmed.ncbi.nlm.nih.gov/25470679
https://pubmed.ncbi.nlm.nih.gov/25470679