Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Darin Zerti"'
Autor:
Birthe Dorgau, Joseph Collin, Agata Rozanska, Darin Zerti, Adrienne Unsworth, Moira Crosier, Rafiqul Hussain, Jonathan Coxhead, Tamil Dhanaseelan, Aara Patel, Jane C. Sowden, David R. FitzPatrick, Rachel Queen, Majlinda Lako
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The emergence of retinal progenitor cells and differentiation to various retinal cell types represent fundamental processes during retinal development. Herein, we provide a comprehensive single cell characterisation of transcriptional and ch
Externí odkaz:
https://doaj.org/article/416ae52d4d2147ef83f5da46162b46af
Autor:
Carla B. Mellough, Joseph Collin, Rachel Queen, Gerrit Hilgen, Birthe Dorgau, Darin Zerti, Majed Felemban, Kathryn White, Evelyne Sernagor, Majlinda Lako
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 7, Pp 694-706 (2019)
Abstract A major goal in the stem cell field is to generate tissues that can be utilized as a universal tool for in vitro models of development and disease, drug development, or as a resource for patients suffering from disease or injury. Great effor
Externí odkaz:
https://doaj.org/article/48026f595dbd4856afad7887514cb82b
Autor:
Rita Maccarone, Cinzia Rapino, Darin Zerti, Monia di Tommaso, Natalia Battista, Stefano Di Marco, Silvia Bisti, Mauro Maccarrone
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166827 (2016)
Experimental studies demonstrated that saffron (Crocus sativus) given as a dietary supplement counteracts the effects of bright continuous light (BCL) exposure in the albino rat retina, preserving both morphology and function and probably acting as a
Externí odkaz:
https://doaj.org/article/c63330b5140143d3ae85832f3b0eea66
Akademický článek
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Autor:
Joseph Collin, Megan S R Hasoon, Darin Zerti, Sarah Hammadi, Birthe Dorgau, Lucy Clarke, David Steel, Rafiqul Hussain, Jonathan Coxhead, Steven Lisgo, Rachel Queen, Majlinda Lako
Publikováno v:
Human Molecular Genetics. 32:1698-1710
Age-related macular degeneration (AMD) is the most prevalent cause of blindness in the developed world. Vision loss in the advanced stages of the disease is caused by atrophy of retinal photoreceptors, overlying retinal pigment epithelium (RPE) and c
Publikováno v:
Current Eye Research
Single-cell sequencing technologies have emerged as a revolutionary tool with transformative new methods to profile genetic, epigenetic, spatial, and lineage information in individual cells. Single-cell RNA sequencing (scRNA-Seq) allows researchers t
Autor:
Majed Felemban, Yuchun Ding, Natalio Krasnogor, Birthe Dorgau, Ali E. Ghareeb, Darin Zerti, Min Yu, Majlinda Lako
Publikováno v:
Stem Cells (Dayton, Ohio)
Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse diseases such as Stargardt's disease, age‐related macular degeneration, and retinitis pigmentosa. The final impact of all retinal dystrophies is the lo
Autor:
Agata Rozanska, Rodrigo Cerna-Chavez, Rachel Queen, Joseph Collin, Darin Zerti, Birthe Dorgau, Chia Shyan Beh, Tracey Davey, Jonathan Coxhead, Rafiqul Hussain, Jumana Al-Aama, David H Steel, Nissim Benvenisty, Lyle Armstrong, Manoj Parulekar, Majlinda Lako
Publikováno v:
Stem cells translational medicine. 11(4)
Retinoblastoma (Rb) is a childhood cancer of the developing retina, accounting for up to 17% of all tumors in infancy. To gain insights into the transcriptional events of cell state transitions during Rb development, we established 2 disease models v
Autor:
Jumana Y. Al-Aama, Nissim Benvenisty, Birthe Dorgau, Rafiqul Hussain, David H. W. Steel, Agata Rozanska, Majlinda Lako, Joseph Collin, Jonathan Coxhead, Manoj Parulekar, Tracey Davey, Rachel Queen, Rodrigo Cerna Chavez, Darin Zerti, Lyle Armstrong
Publikováno v:
SSRN Electronic Journal.
Retinoblastoma (Rb) is a childhood cancer of the developing retina in response to bi-allelic inactivation of RB1 or MYCN amplification, accounting for up to 17% of all tumours in infancy. To gain insights into the transcriptional events of cell state
Autor:
Marina Moya Molina, Sarah Mearns, Darin Zerti, Birthe Dorgau, Roman Bauer, Jumana Y. Al-Aama, Majlinda Lako
Development of the retina is regulated by growth factors, such as insulin-like growth factors 1 and 2 (IGF-1/2), which coordinate proliferation, differentiation, and maturation of the neuroepithelial precursors cells. In the circulation, IGF-1/2 are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6cf7df442cdf201e269dbaf3736875
http://hdl.handle.net/11697/157503
http://hdl.handle.net/11697/157503