Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Darin T. Lynch"'
Autor:
Michael W. Greene, David E. Blask, Erin M. Dauchy, Christine M. Burrington, Potjana Jitawatanarat, Darin T. Lynch, Steven S. Wu, Paul C. Tirrell, Robert T. Dauchy, Jinghai Wu
Regulation of diurnal and circadian rhythms and cell proliferation are coupled in all mammals, including humans. However, the molecular mechanisms by which diurnal and circadian rhythms regulate cell proliferation are relatively poorly understood. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd301fbe7bd1536be5585a6ac85863e5
https://doi.org/10.1158/0008-5472.c.6503115.v1
https://doi.org/10.1158/0008-5472.c.6503115.v1
Autor:
Michael W. Greene, David E. Blask, Erin M. Dauchy, Christine M. Burrington, Potjana Jitawatanarat, Darin T. Lynch, Steven S. Wu, Paul C. Tirrell, Robert T. Dauchy, Jinghai Wu
Supplementary Figure 1 from Light at Night Activates IGF-1R/PDK1 Signaling and Accelerates Tumor Growth in Human Breast Cancer Xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3464e865a622ad7bff98f03b7b10ca59
https://doi.org/10.1158/0008-5472.22390992.v1
https://doi.org/10.1158/0008-5472.22390992.v1
Autor:
Michael W Greene, Christine M Burrington, Darin T Lynch, Samantha K Davenport, Andrew K Johnson, Melissa J Horsman, Saleem Chowdhry, Jian Zhang, Janet D Sparks, Paul C Tirrell
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85848 (2014)
Steatosis, oxidative stress, and apoptosis underlie the development of nonalcoholic steatohepatitis (NASH). Protein kinase C delta (PKCδ) has been implicated in fatty liver disease and is activated in the methionine and choline-deficient (MCD) diet
Externí odkaz:
https://doaj.org/article/6daa2d05b7dd4516b00fc6449160a980
Autor:
Darin T. Lynch, Michael W. Greene, David E. Blask, Brian A. Reis, Melissa J. Horsman, Erin A. Gillaspie, Paul C. Tirrell, Christine M. Burrington, Ann Marie O'Neill, Robert T. Dauchy
Publikováno v:
Nutrition and cancer. 70(2)
The association between a Western Diet and colon cancer suggests that dietary factors and/or obesity may contribute to cancer progression. Our objective was to develop a new animal model of obesity and the associated pathophysiology to investigate hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec20d8d0842752df2e83031ac86a5c18
https://pubmed.ncbi.nlm.nih.gov/29313726
https://pubmed.ncbi.nlm.nih.gov/29313726
Autor:
Darin T. Lynch, Michael W. Greene, Melissa J. Horsman, Ann Marie O'Neill, Christine M. Burrington, Erin A. Gillaspie
Publikováno v:
Nutrition research (New York, N.Y.). 36(12)
Strong epidemiologic evidence links colon cancer to obesity. The increasing worldwide incidence of colon cancer has been linked to the spread of the Western lifestyle, and in particular consumption of a high-fat Western diet. In this study, our objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7309122fc410fe145407b1fcb8bc8a3
https://pubmed.ncbi.nlm.nih.gov/27866828
https://pubmed.ncbi.nlm.nih.gov/27866828
Autor:
Darin T. Lynch, Erin M. Dauchy, Steven S. Wu, David E. Blask, Michael W. Greene, Potjana Jitawatanarat, Christine M. Burrington, Paul C. Tirrell, Jinghai Wu, Robert T. Dauchy
Publikováno v:
Cancer Research. 71:2622-2631
Regulation of diurnal and circadian rhythms and cell proliferation are coupled in all mammals, including humans. However, the molecular mechanisms by which diurnal and circadian rhythms regulate cell proliferation are relatively poorly understood. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cee96bb74dd12bafa1791a582bd516f
https://doi.org/10.1158/0008-5472.can-10-3837
https://doi.org/10.1158/0008-5472.can-10-3837
Autor:
Darin T. Lynch, Niyutchai Chaithongdi, Yuwen Luo, Michael W. Greene, Christine M. Burrington, Mary S. Ruhoff
Publikováno v:
The Journal of nutritional biochemistry. 25(3)
Insulin resistance can arise when pathological levels of free fatty acids (FFAs) and proinflammatory cytokines disrupt insulin signaling. Protein kinase C delta (PKCδ) is a FFA- and a proinflammatory cytokine-regulated protein kinase that is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f575eb476f852ffa4c24ab8aaca0a9
https://pubmed.ncbi.nlm.nih.gov/24524901
https://pubmed.ncbi.nlm.nih.gov/24524901
Autor:
Robert T, Dauchy, Erin M, Dauchy, Leslie K, Davidson, Jean A, Krause, Darin T, Lynch, Paul C, Tirrell, Robert P, Tirrell, Leonard A, Sauer, Peter, Van der Riet, David E, Blask
Publikováno v:
Comparative medicine. 57(4)
Melatonin and eicosapentaenoic and 10t,12c-conjugated linoleic acids suppress the growth-stimulating effects of linoleic acid (LA) and its metabolism to the mitogenic agent 13-(S)-hydroxyoctadecadienoic acid (13-(S)-HODE) in established rodent tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13aac5d5706ccce595a54bf75ce53e4d
https://pubmed.ncbi.nlm.nih.gov/17803052
https://pubmed.ncbi.nlm.nih.gov/17803052
Autor:
Leonard A. Sauer, Darin T. Lynch, Jean A. Krause, Laura C. Smith, Leslie K. Davidson, Robert T. Dauchy, David E. Blask, Erin M. Dauchy
Publikováno v:
Nutrition and cancer. 56(2)
Dietary fish oil decreases growth of solid tumors in rodents. Mechanisms for this effect are not well defined. In rat hepatoma 7288CTC, short-term (1-2 h) treatment with eicosapentaenoic acid during perfusion in situ reduced fatty acid uptake and [(3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caec08ef2198b4074c2b714b5e916260
https://pubmed.ncbi.nlm.nih.gov/17474866
https://pubmed.ncbi.nlm.nih.gov/17474866
Autor:
Erin M, Dauchy, Robert T, Dauchy, Leslie K, Davidson, Darin T, Lynch, Jean A, Krause, Lia M, Blue, Leonard A, Sauer, David E, Blask
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS. 45(3)
We developed an artificial lung and catheter system for perfusing tissue-isolated tumors in situ that dramatically minimizes perfusate delivery time. Our investigations demonstrated that the circadian neurohormone melatonin (MLT), eicosapentaenoic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::874cff4fb22204c13ea0be3c39c2c1af
https://pubmed.ncbi.nlm.nih.gov/16642969
https://pubmed.ncbi.nlm.nih.gov/16642969