Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Darin P, Clark"'
Publikováno v:
Tomography, Vol 9, Iss 4, Pp 1286-1302 (2023)
Photon-counting CT (PCCT) is powerful for spectral imaging and material decomposition but produces noisy weighted filtered backprojection (wFBP) reconstructions. Although iterative reconstruction effectively denoises these images, it requires extensi
Externí odkaz:
https://doaj.org/article/a14cc4f43cff4b4bae1601c2a616a824
Autor:
Rohan Nadkarni, Zay Yar Han, Robert J Anderson, Alex J Allphin, Darin P Clark, Alexandra Badea, Cristian T Badea
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303288 (2024)
BackgroundBrain region segmentation and morphometry in humanized apolipoprotein E (APOE) mouse models with a human NOS2 background (HN) contribute to Alzheimer's disease (AD) research by demonstrating how various risk factors affect the brain. Photon
Externí odkaz:
https://doaj.org/article/d4e74ba18b244235b08cd7e48428e2f1
Autor:
Alex J. Allphin, Yvonne M. Mowery, Kyle J. Lafata, Darin P. Clark, Alex M. Bassil, Rico Castillo, Diana Odhiambo, Matthew D. Holbrook, Ketan B. Ghaghada, Cristian T. Badea
Publikováno v:
Tomography, Vol 8, Iss 2, Pp 740-753 (2022)
The purpose of this study was to investigate if radiomic analysis based on spectral micro-CT with nanoparticle contrast-enhancement can differentiate tumors based on lymphocyte burden. High mutational load transplant soft tissue sarcomas were initiat
Externí odkaz:
https://doaj.org/article/71a3509d5ec44fb3ad3fbf31d1364bbf
Autor:
Alex J Allphin, Ali Mahzarnia, Darin P Clark, Yi Qi, Zay Y Han, Prajwal Bhandari, Ketan B Ghaghada, Alexandra Badea, Cristian T Badea
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0291733 (2023)
BackgroundCardiovascular disease (CVD) is associated with the apolipoprotein E (APOE) gene and lipid metabolism. This study aimed to develop an imaging-based pipeline to comprehensively assess cardiac structure and function in mouse models expressing
Externí odkaz:
https://doaj.org/article/768e4b5423604938a362b839e745ecfc
Autor:
Matthew D. Holbrook, Darin P. Clark, Rutulkumar Patel, Yi Qi, Alex M. Bassil, Yvonne M. Mowery, Cristian T. Badea
Publikováno v:
Tomography, Vol 7, Iss 3, Pp 358-372 (2021)
We are developing imaging methods for a co-clinical trial investigating synergy between immunotherapy and radiotherapy. We perform longitudinal micro-computed tomography (micro-CT) of mice to detect lung metastasis after treatment. This work explores
Externí odkaz:
https://doaj.org/article/c6583fc9293749fc904d6f46808f8805
Publikováno v:
Tomography; Volume 9; Issue 4; Pages: 1286-1302
Photon-counting CT (PCCT) is powerful for spectral imaging and material decomposition but produces noisy weighted filtered backprojection (wFBP) reconstructions. Although iterative reconstruction effectively denoises these images, it requires extensi
Autor:
Yifu Ding, Daniel J Vanselow, Maksim A Yakovlev, Spencer R Katz, Alex Y Lin, Darin P Clark, Phillip Vargas, Xuying Xin, Jean E Copper, Victor A Canfield, Khai C Ang, Yuxin Wang, Xianghui Xiao, Francesco De Carlo, Damian B van Rossum, Patrick La Riviere, Keith C Cheng
Publikováno v:
eLife, Vol 8 (2019)
Organismal phenotypes frequently involve multiple organ systems. Histology is a powerful way to detect cellular and tissue phenotypes, but is largely descriptive and subjective. To determine how synchrotron-based X-ray micro-tomography (micro-CT) can
Externí odkaz:
https://doaj.org/article/a4fe8abecd5345ed8e6fd5e965f76360
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0218417 (2019)
The maturation of photon-counting detector (PCD) technology promises to enhance routine CT imaging applications with high-fidelity spectral information. In this paper, we demonstrate the power of this synergy and our complementary reconstruction tech
Externí odkaz:
https://doaj.org/article/2b26e426e46e44db9da5e24ff810f65a
Autor:
Fides R. Schwartz, Darin P. Clark, Francesca Rigiroli, Kevin Kalisz, Benjamin Wildman-Tobriner, Sarah Thomas, Joshua Wilson, Cristian T. Badea, Daniele Marin
Publikováno v:
European Radiology.
Publikováno v:
Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging.