Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Darin E"'
Autor:
Darin E. W. Johnson, Catherine Powell
Publikováno v:
AJIL Unbound, Vol 117, Pp 37-42 (2023)
While other scholars have discussed Dr. Pauli Murray's remarkable contributions to race and sex equality law,1 few, if any, have placed her contributions within the context of the broader tradition of human rights law. And yet, she identified herself
Externí odkaz:
https://doaj.org/article/d8b8f9990e994342b10652fe920094a2
Autor:
Stephen A. Shrum, Ujwani Nukala, Shivangi Shrimali, Edith Nathalie Pineda, Kimberly J. Krager, Shraddha Thakkar, Darin E. Jones, Rupak Pathak, Philip J. Breen, Nukhet Aykin-Burns, Cesar M. Compadre
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1987 (2023)
Tocotrienols have powerful radioprotective properties in multiple organ systems and are promising candidates for development as clinically effective radiation countermeasures. To facilitate their development as clinical radiation countermeasures, it
Externí odkaz:
https://doaj.org/article/025774aeb31a47a8886e67dfde8f0adf
Autor:
Shivangi Shrimali, Awantika Singh, Rajeshkumar Manian, Shraddha Thakkar, Darin E. Jones, Nukhet Aykin-Burns, Philip Breen, Cesar M. Compadre
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 136-137 (2023)
OBJECTIVES/GOALS: We have designed an analogue of the Vitamin E tocotrienols called tocoflexol, which improves their pharmacokinetic limitations to make it an effective radiation medical countermeasure. Our goal is to demonstrate that tocoflexol is a
Externí odkaz:
https://doaj.org/article/201ed12be68747c2b703bbceb902db82
Autor:
Megan B. Stemberger, Julia A. Ju, Keyata N. Thompson, Trevor J. Mathias, Alexandra E. Jerrett, Katarina T. Chang, Eleanor C. Ory, David A. Annis, Makenzy L. Mull, Darin E. Gilchrist, Michele I. Vitolo, Stuart S. Martin
Publikováno v:
Cells, Vol 12, Iss 9, p 1266 (2023)
Levels of hydrogen peroxide are highly elevated in the breast tumor microenvironment compared to normal tissue. Production of hydrogen peroxide is implicated in the mechanism of action of many anticancer therapies. Several lines of evidence suggest h
Externí odkaz:
https://doaj.org/article/fff120d70ebf46c392e1750ff30f723f
Autor:
Jerry H. Houl, Zu Ye, Chris A. Brosey, Lakshitha P. F. Balapiti-Modarage, Sarita Namjoshi, Albino Bacolla, Daniel Laverty, Brian L. Walker, Yasin Pourfarjam, Leslie S. Warden, Naga Babu Chinnam, Davide Moiani, Roderick A. Stegeman, Mei-Kuang Chen, Mien-Chie Hung, Zachary D. Nagel, Tom Ellenberger, In-Kwon Kim, Darin E. Jones, Zamal Ahmed, John A. Tainer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
PARG catalyzes the removal of poly(ADP-ribose) (PAR) from target proteins and executes critical functions in the DNA damage response. Here the authors provide structural and biological insight with small molecule PARG inhibitors and show that PARG in
Externí odkaz:
https://doaj.org/article/b8239efdcde244de83ae43188c91b2d3
Autor:
David E. Mery, Amanda J. Compadre, Paola E. Ordóñez, Edward J. Selvik, Vladimir Morocho, Jorge Contreras, Omar Malagón, Darin E. Jones, Philip J. Breen, Michael J. Balick, Flavio G. Gaudio, Monica L. Guzman, Cesar M. Compadre
Publikováno v:
Molecules, Vol 27, Iss 9, p 2928 (2022)
A method to identify anticancer compounds in plants was proposed based on the hypothesis that these compounds are primarily present in plants to provide them with an ecological advantage over neighboring plants and other competitors. According to thi
Externí odkaz:
https://doaj.org/article/40f8a2a0e8cf443b9b3ef69fd55bc294
Autor:
Paola E. Ordóñez, David E. Mery, Krishan K. Sharma, Saumyadip Nemu, William F. Reynolds, Raul G. Enriquez, Darcy C. Burns, Omar Malagón, Darin E. Jones, Monica L. Guzman, Cesar M. Compadre
Publikováno v:
Molecules, Vol 25, Iss 20, p 4825 (2020)
Dehydroleucodine is a bioactive sesquiterpene lactone. Herein, four dehydroleucodine amino derivatives were synthesized using the amines proline, piperidine, morpholine, and tyramine, and spectroscopic methods and single-crystal X-ray diffraction una
Externí odkaz:
https://doaj.org/article/27dc93c9ea5d4b6f8fc9e934ac2382e5
Autor:
Darin E. Olson
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 9, Iss C, Pp 66-67 (2017)
Externí odkaz:
https://doaj.org/article/7b1ca231a7154569bcde7082f972d72e
Autor:
Shuo You, Mallappa Anitha, Sean MD deSouza, Dingwu Jia, Xianghua Lu, Miroslaw Kozlowski, Darin E Olson, Shanthi Srinivasan, Peter M Thulé
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Depending on the population examined, from 6 to 83% of people with diabetes mellitus exhibit symptoms of altered gut motility, manifesting as dysphagia, reflux, early satiety, nausea, abdominal pain, diarrhea, or constipation. Hyperglycemia-induced c
Externí odkaz:
https://doaj.org/article/4cca0afd404843c7aadc912497bb4af5
Autor:
Darin E. Olson, MD, PhD
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 4, Iss C, p 66 (2016)
Externí odkaz:
https://doaj.org/article/264e851de67847b586a1166eb39ee9ad