Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Darin D. DuMez"'
Autor:
Darin D. DuMez, Heather E. Tibbles, Taracad K. Venkatachalam, Alexei O. Vassilev, Fatih M. Uckun
Publikováno v:
Current Drug Targets. 7:327-343
Multifunctional rational drug design of protein tyrosine kinases inhibitors allows a potent drug to be utilized to treat more than one disease for greater patient benefits. Many protein tyrosine kinases (PTK), including Janus kinase 3 (JAK3) and Brut
Publikováno v:
Journal of Inorganic Biochemistry. 83:151-160
The ability of bis(cyclopentadienyl)-vanadium(IV) (acetylacetonate) ( 1 ) to initiate oxygen-dependent lipid peroxidation in zwitterionic liposomal membranes was examined in detail. A comparison of the rates of the lipid peroxidation reaction demonst
Autor:
W. Stephen McNeil, Darin D. DuMez, James M. Mayer, Thomas J. Crevier, Brian K. Bennett, Yoshihiro Matano
Publikováno v:
Journal of Organometallic Chemistry. 591:96-103
Cyclic voltammetry has been used to study the electrochemical properties of 29 isoelectronic and isostructural osmium(VI)nitrido, rhenium(V)oxo, and rhenium(V)imido complexes of the form Tp (*) M(E)(X)(Y) [Tp (*) =Tp, HB(pz) 3 ; or Tp * , HB
Publikováno v:
Organometallics. 18:3715-3727
Treatment of the d2 rhenium tolylimido complex TpRe(NTol)X2 with RMgX, RLi, or organozinc reagents yields TpRe(NTol)(R)X [R = Ph, Me, Et, i-Pr, n-Bu; X = Cl or I; Tol = p-tolyl; Tp = hydrotris(1-pyrazolyl)borate] or TpRe(NTol)R2 (R = Ph, Me). Iodide
Autor:
Ann T. Kotchevar, John T Peiterson, Fatih M. Uckun, Phalguni Ghosh, Darin D. DuMez, Sutapa Ghosh
Publikováno v:
Inorganic Chemistry. 38:3730-3737
The reaction of in situ generated Cp(2)V(OTf)(2) (Cp = cyclopentadienyl; OTf = O(3)SCF(3)) with excess 1,10-phenanthroline and 2,2'-bipyridine yields the d(1) vanadocene coordination compounds [Cp(2)V(phen)][OTf](2) (1) and [Cp(2)V(bpy)][OTf](2) (2),
Autor:
Darin D. DuMez, James M. Mayer
Publikováno v:
Inorganic Chemistry. 37:445-453
Reaction of rhenium(V)-oxo-halo-triflate complexes (HB(pz)(3))ReO(X)OTf (1, X = Cl, Br, I) with 1 equiv of pyridine N-oxide forms rare d(1) rhenium(VI) cis-dioxo compounds (HB(pz)(3))ReO(2)X (2, X = Cl, Br, I). This reaction likely occurs by initial
Autor:
Darin D. DuMez, James M. Mayer
Publikováno v:
Inorganic Chemistry. 34:6396-6401
New rhenium(V) oxo-alkoxide compounds (HBpz3)ReO(OR)Z (R = Me (l), Et (2), 'Pr (3), "Bu (4), CHrPh (5)) have been prepared in good yields from reaction of (HBpz3)ReOClZ with excess alcohol in the presence of NEt3 [HBpz3 = hydrotris( 1-pyrazoly1)borat
Publikováno v:
Arzneimittel-Forschung. 57(2)
The in vitro potency of GMP-grade stampidine (CAS 217178-62-6) was examined against 3 clinical HIV-1 isolates and 6 recombinant HIV-1 clones with multi-NRTI resistance (NRTI: nucleoside reverse transcriptase inhibitors). GMP-grade stampidine active d
Publikováno v:
ChemInform. 37
The arylphosphoramidate derivative of stavudine (STV, d4T, 2',3'-didehydro-3'-deoxythymidine, CAS 3056-17-5), stampidine (STAMP, DDE-113, HI-113, N-[p-(4-bromophenyl)-2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester, CAS 217178-62-6), i
Fluoride Reactions with Hydrotris(pyrazolyl)borate Rhenium Oxo Complexes: Re-F vs B-F Bond Formation
Publikováno v:
Inorganic chemistry. 38(14)
Rhenium-oxo-fluoride complexes are readily prepared using hydrotris(3,5-dimethyl-1-pyrazolyl)borate [HB(3,5-Me(2)pz)(3)(-), Tp] as a supporting ligand. For instance, treatment of TpRe(O)(OH)Cl with concentrated aqueous HF cleanly forms the chloro-flu