Deciphering Aspergillus fumigatus cyp51A-mediated triazole resistance by pyrosequencing of respiratory specimens

Autor: Darin Hassan, Rikesh Masania, Malcolm Richardson, Caroline B. Moore, Lilyann Novak-Frazer, David W. Denning, Samuel P Anees-Hill, Riina Rautemaa-Richardson

Publikováno v: Novak-Frazer, L, Anees-Hill, S P, Hassan, D, Masania, R, Moore, C B, Richardson, M D, Denning, D W & Rautemaa-Richardson, R 2020, ' Deciphering Aspergillus fumigatus cyp51A-mediated triazole resistance by pyrosequencing of respiratory specimens ', Journal of Antimicrobial Chemotherapy, vol. 75, no. 12, pp. 3501-3509 . https://doi.org/10.1093/jac/dkaa357
Journal of Antimicrobial Chemotherapy

Background Infections caused by triazole drug-resistant Aspergillus fumigatus are an increasing problem. The sensitivity of standard culture is poor, abrogating susceptibility testing. Early detection of resistance can improve patient outcomes, yet t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8f8e246b6bf84fef3aeec86e5be816
https://www.research.manchester.ac.uk/portal/en/publications/deciphering-aspergillus-fumigatus-cyp51amediated-triazole-resistance-by-pyrosequencing-of-respiratory-specimens(898246bf-b520-4b34-b344-28f6f2e83832).html

Structure and oligomerization of the PilC type IV pilus biogenesis protein from Thermus thermophilus

Autor: Vijaykumar, Karuppiah, Darin, Hassan, Muhammad, Saleem, Jeremy P, Derrick

Publikováno v: Proteins. 78(9)

Type IV pili are expressed from a wide variety of Gram-negative bacteria and play a major role in host cell adhesion and bacterial motility. PilC is one of at least a dozen different proteins that are implicated in Type IV pilus assembly in Thermus t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1009efd1fe2e4155fdecad464bce5a3
https://pubmed.ncbi.nlm.nih.gov/20455262