Structure-Activity Relationship of Antibody-Oligonucleotide Conjugates: Evaluating Bioconjugation Strategies for Antibody-Phosphorodiamidate Morpholino Oligomer Conjugates for Drug Development.

Autor: Cochran M; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Marks I; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Albin T; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Arias D; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Kovach P; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Darimont B; CYTOO, 7 Parv. Louis Néel CS 20050, 38040 Grenoble, France., Huang H; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Etxaniz U; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Kwon HW; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Shi Y; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Diaz M; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Tyaglo O; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Levin A; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States., Doppalapudi VR; Avidity Biosciences, Inc., 10578 Science Center Drive Suite 125, San Diego, California 92121, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Sep 12; Vol. 67 (17), pp. 14868-14884. Date of Electronic Publication: 2024 Aug 28.

Unliganded and Hormone-Bound Glucocorticoid Receptors Interact with Distinct Hydrophobic Sites in the Hsp90 C-Terminal Domain

Autor: Fang, L., Ricketson, D., Getubig, L., Darimont, B.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2006 Dec 01. 103(49), 18487-18492.

Externí odkaz: https://www.jstor.org/stable/30051140

FP.15 AI-powered cell profiling enables the functional evaluation of therapies targeting muscle disorders in patient-derived myotubes

Autor: Darimont, B., Lorintiu, O., Champetier, T., Duchemin-Pelletier, E., Flaender, M., Chapuis-Perrot, V., Young, J., Gaston, C., Griveau, L., Papin, M., Poydenot, P., Ventre, E., Selig, L.

Publikováno v: In Neuromuscular Disorders October 2022 32 Supplement 1:S66-S66

Analysis of the Setomimycin Biosynthetic Gene Cluster from Streptomyces nojiriensis JCM3382 and Evaluation of Its α-Glucosidase Inhibitory Activity Using Molecular Docking and Molecular Dynamics Simulations.

Autor: Hyun, Kyung-A¹ (AUTHOR) kah990626@gmail.com, Liang, Xuhui² (AUTHOR) lxh03036@naver.com, Xu, Yang² (AUTHOR) iamxuyang1990@gmail.com, Kim, Seung-Young³ (AUTHOR) sykim01@sunmoon.ac.kr, Boo, Kyung-Hwan¹ (AUTHOR) khboo@jejunu.ac.kr, Park, Jin-Soo⁴ (AUTHOR) jinsoopark@kist.re.kr, Chi, Won-Jae⁵ (AUTHOR) wjchi76@korea.kr, Hyun, Chang-Gu² (AUTHOR) wjchi76@korea.kr

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10758. 20p.

Nucleic Acid Armor: Fortifying RNA Therapeutics through Delivery and Targeting Innovations for Immunotherapy.

Autor: Jiang, Yi¹ (AUTHOR) jiangyi@stu.ouc.edu.cn, Jiang, Bolong¹ (AUTHOR) jiangbolong@stu.ouc.edu.cn, Wang, Zhenru² (AUTHOR) zhenru_wang@163.com, Li, Yuxi¹ (AUTHOR) liyuyuxi@163.com, Cheung, James Chung Wai³ (AUTHOR) james.chungwai.cheung@polyu.edu.hk, Yin, Bohan^1,4 (AUTHOR) bohanyin@ouc.edu.cn, Wong, Siu Hong Dexter^1,4 (AUTHOR) bohanyin@ouc.edu.cn

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8888. 25p.