Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Darian S. James"'
Autor:
Darian S. James, Paul J. Campagnola
Publikováno v:
BME Frontiers, Vol 2021 (2021)
Second harmonic generation (SHG) and third harmonic generation (THG) microscopies have emerged as powerful imaging modalities to examine structural properties of a wide range of biological tissues. Although SHG and THG arise from very different contr
Externí odkaz:
https://doaj.org/article/c2a9b7e3705440d7baab5fa6cd309f28
Publikováno v:
Multiphoton Microscopy in the Biomedical Sciences XXIII.
Publikováno v:
Ultrafast Nonlinear Imaging and Spectroscopy IX.
We have developed Second Harmonic Generation (SHG) microscope tools to selectively and specifically probe changes in collagen organization in diseased tissues. Using a novel form of 3D machine learning, we successfully classified six types of ovarian
Publikováno v:
Journal of Biomedical Optics
Significance: Idiopathic pulmonary fibrosis (IPF) patients have a poor prognosis with short lifespan following diagnosis as there are limited effective treatment options. Despite matrix stiffening being the hallmark of the disease there remains a lac
Publikováno v:
Multiphoton Microscopy in the Biomedical Sciences XX.
Autor:
Zachary Alden, Alexander N. Jambor, Paul J. Campagnola, Nathan Sandbo, Darian S. James, Hsin-Yu Chang, Karissa Tilbury
Publikováno v:
Journal of Biomedical Optics
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis with short lifespan following diagnosis as patients have limited effective treatment options. A fundamental limitation is a lack of knowledge of the underlying collagen
Publikováno v:
Multiphoton Microscopy in the Biomedical Sciences XIX.
Both ovarian cancer and idiopathic pulmonary fibrosis (IPF) are accompanied by significant collagen remodeling in the respective extracellular matrix (ECM). These diseases have similar attributes and collagen alterations can be probed with the same m
Publikováno v:
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP).
Autor:
Alyssa Walker, Pamela K. Kreeger, Veronica L. Porubsky, Darian S. James, Will Flanigan, Paul Weisman, Andrew J. Fleszar, Paul J. Campagnola
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031902-031902-15 (2018)
A growing body of research supports the idea that the fallopian tube epithelium (FTE) is the precursor for most high-grade serous ovarian canacers (HGSOC) but that the ovary plays a critical role in tumor metastasis. Cortical inclusion cysts (CICs) i