Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Daria V. Dibrova"'
Autor:
Gregory A. Shilovsky, Daria V. Dibrova
Publikováno v:
Life, Vol 13, Iss 4, p 1045 (2023)
Keap1 (Kelch-like ECH-associated protein 1) is one of the major negative regulators of the transcription factor Nrf2 (nuclear factor erythroid-2-related factor 2), which induces the expression of numerous proteins defending the cell against different
Externí odkaz:
https://doaj.org/article/2dee8ff6f33e4c2e86f5f21097e90d2e
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1346 (2022)
To clarify the obscure hydrolysis mechanism of ubiquitous P-loop-fold nucleoside triphosphatases (Walker NTPases), we analysed the structures of 3136 catalytic sites with bound Mg-NTP complexes or their analogues. Our results are presented in two art
Externí odkaz:
https://doaj.org/article/fd4eb8263e484062bc9e4f10ac24a55d
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1345 (2022)
The P-loop fold nucleoside triphosphate (NTP) hydrolases (also known as Walker NTPases) function as ATPases, GTPases, and ATP synthases, are often of medical importance, and represent one of the largest and evolutionarily oldest families of enzymes.
Externí odkaz:
https://doaj.org/article/d8abcd88de984485b7e8078874551d10
Autor:
Daria V. Dibrova, Kirill A. Konovalov, Vadim V. Perekhvatov, Konstantin V. Skulachev, Armen Y. Mulkidjanian
Publikováno v:
Biology Direct, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background The Clusters of Orthologous Groups (COGs) of proteins systematize evolutionary related proteins into specific groups with similar functions. However, the available databases do not provide means to assess the extent of similarity
Externí odkaz:
https://doaj.org/article/171e160e6f454fd794c6b493fde6cdf0
Autor:
Olesya I. Klimchuk, Kirill A. Konovalov, Vadim V. Perekhvatov, Konstantin V. Skulachev, Daria V. Dibrova, Armen Y. Mulkidjanian
Publikováno v:
Biology Direct, Vol 12, Iss 1, Pp 1-7 (2017)
Abstract Background In prokaryotic genomes, functionally coupled genes can be organized in conserved gene clusters enabling their coordinated regulation. Such clusters could contain one or several operons, which are groups of co-transcribed genes. Th
Externí odkaz:
https://doaj.org/article/2572dc15872a4fc1883e8320e4992e60
Although P-loop fold nucleoside triphosphatases (also known as Walker NTPases) are ubiquitous, their catalytic mechanism remains obscure. Based on a comparative structural analysis of 3136 Mg-NTP-containing catalytic sites, we propose a common scheme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ebad826ce72500a58e28465efdbdc2
https://doi.org/10.1101/2022.06.23.497301
https://doi.org/10.1101/2022.06.23.497301
Autor:
Dmitry A. Cherepanov, I. M. Bushmakin, J. D. Belyaeva, Maria I. Kozlova, Daria N. Shalaeva, Armen Y. Mulkidjanian, Daria V. Dibrova
Publikováno v:
Biochemistry (Moscow). 85:1518-1542
In 1986, Vladimir Skulachev and his colleagues coined the term "Sodium World" for the group of diverse organisms with sodium (Na)-based bioenergetics. Albeit only few such organisms had been discovered by that time, the authors insightfully noted tha
Autor:
Ilya M. Bushmakin, Daria N. Shalaeva, Daria V. Dibrova, Maria I. Kozlova, Olesya I. Klimchuk, Armen Y. Mulkidjanian, Dmitry A. Cherepanov, Julia D. Belyaeva
Publikováno v:
Proceedings of the 3rd International Conference in celebration of the 85th birthday of professor V.P. Skulachev. Abstract Book.
Publikováno v:
Biochemical and Biophysical Research Communications. 496:529-535
The Arp2/3 complex plays a key role in nucleating actin filaments branching. The glia maturation factor (GMF) competes with activators for interacting with the Arp2/3 complex and initiates the debranching of actin filaments. In this study, we perform
Publikováno v:
Biochemistry (Moscow). 81:770-784
We performed phylogenomic analysis of the catalytic core of NADH:quinone oxidoreductases of type 1 (NDH-1). Analysis of phylogenetic trees, as constructed for the core subunits of NDH-1, revealed fundamental differences in their topologies. In the ca