Výsledky vyhledávání - "Daria Sizova"

Functional characterization of a humanPOU1F1mutation associated with isolated growth hormone deficiency: a novel etiology for IGHD

Autor: Bruno Copin, Marie-Laure Sobrier, Bruno Leheup, Philippe Duquesnoy, Alfredo Penzo, Ben Z. Stanger, Stephen A. Liebhaber, Christelle Perez, Daria Sizova, Serge Amselem, Tahar Bouceba, Nancy E. Cooke, Yu-Cheng Tsai

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, 2016, 25 (3), pp.472-483. ⟨10.1093/hmg/ddv486⟩
Human Molecular Genetics, Oxford University Press (OUP), 2016, 25 (3), pp.472-483. ⟨10.1093/hmg/ddv486⟩

International audience; POU1F1, a pituitary-specific POU-homeo domain transcription factor, plays an essential role in the specification of the somatotroph, lactotroph and thyrotroph lineages and in the activation of GH1, PRL and TSHβ transcription.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca80e74801025c697cf43458bd275140
https://doi.org/10.1093/hmg/ddv486

Zobrazit plný text záznamu

Renalase regulates renal dopamine and phosphate metabolism

Autor: Manuel Pestana, Benedita Sampaio-Maia, Daria Sizova, Janete Quelhas-Santos, Heino Velazquez, Gary V. Desir

Publikováno v: American Journal of Physiology-Renal Physiology. 305:F839-F844

Renalase is a kidney-secreted catecholamines-degrading enzyme whose expression and activity are downregulated by increased dietary phosphate. A renalase knockout (KO) mouse model was used to explore the mechanisms mediating renalase's effect on phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c54d08775ae2967e57f370281f5805e
https://doi.org/10.1152/ajprenal.00616.2012

Zobrazit plný text záznamu

Epigenetic Activation of the Human Growth Hormone Gene Cluster during Placental Cytotrophoblast Differentiation

Autor: Nancy E. Cooke, Stephen A. Liebhaber, Atsushi P. Kimura, Stuart Handwerger, Daria Sizova

Publikováno v: Molecular and Cellular Biology. 27:6555-6568

The hGH cluster contains a single human pituitary growth hormone gene (hGH-N) and four placenta-specific paralogs. Activation of the cluster in both tissues depends on 5' remote regulatory elements. The pituitary-specific locus control elements DNase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df836167253c0b6f5e1bc99ab555677f
https://doi.org/10.1128/mcb.00273-07

Zobrazit plný text záznamu

The R280H X-ray cross-complementing 1 germline variant induces genomic instability and cellular transformation

Autor: Daria Sizova, Agnes Keh, Joann B. Sweasy, Ben F. Taylor

Publikováno v: DNA repair. 31

X-ray repair cross complementing protein 1 (XRCC1) plays an important role in base excision DNA repair (BER) as a scaffolding protein for BER enzymes. BER is one of the basic DNA repair pathways repairing greater than 20,000 endogenous lesions per ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6e7c1abbb91e6ac262f564ea228f9e
https://pubmed.ncbi.nlm.nih.gov/26011397

Zobrazit plný text záznamu

Internal ribosome entry sites of viral and cellular RNAs

Autor: I N Shatskiĭ, Daria Sizova

Publikováno v: Molecular Biology. 34:157-167

In recent years mechanism of internal initation of translation in eukaryotic cells commands the attention of molecular biologists in increasing frequency. Ten years ago, experiments with picornaviruses demonstrated the ability of 40S ribosomal subuni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9e6806e79d6e6d2db87c0a9d9cdf989
https://doi.org/10.1007/bf02759634

Zobrazit plný text záznamu

Specific Interaction of Eukaryotic Translation Initiation Factor 3 with the 5′ Nontranslated Regions of Hepatitis C Virus and Classical Swine Fever Virus RNAs

Autor: Ivan N. Shatsky, Victoria G. Kolupaeva, Tatyana V. Pestova, Christopher U.T. Hellen, Daria Sizova

Publikováno v: Journal of Virology. 72:4775-4782

Translation of hepatitis C virus (HCV) and classical swine fever virus (CSFV) RNAs is initiated by cap-independent attachment (internal entry) of ribosomes to the ∼350-nucleotide internal ribosomal entry segment (IRES) at the 5′ end of both RNAs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371e3352f8d8a434f610f874c897425e
https://doi.org/10.1128/jvi.72.6.4775-4782.1998

Zobrazit plný text záznamu

Protein Expression Profile of Alzheimer’s Disease Mouse Model Generated by Difference Gel Electrophoresis (DIGE) Approach

Autor: Daria Sizova

Publikováno v: Genomics, Proteomics, and the Nervous System ISBN: 9781441971968

Alzheimer’s disease (AD) is a well-described neurological disorder characterized by the presence of a number of biological processes. Deposition of β-amyloid plaques in brain, one of the main features of AD pathology, was successfully modeled in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1f381904631ceee5590b7fabd212d2b
https://doi.org/10.1007/978-1-4419-7197-5_19

Zobrazit plný text záznamu

Proteomic analysis of brain tissue from an Alzheimer's disease mouse model by two-dimensional difference gel electrophoresis

Autor: Anthony A. High, François Delalande, Parker Fabienne, Daria Sizova, Florence Poirier, Anita Diu-Hercend, Duchesne Marc, Alain Van Dorsselaer, Elodie Charbaut

Publikováno v: Neurobiology of aging. 28(3)

We used a beta-amyloid precursor protein (APP) transgenic (Tg) mouse model that displays some of the typical Alzheimer-associated pathological features to study the brain proteoma associated with amyloid plaque deposition. Two groups (male and female

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abbb9d79c15f27581f7b9207cadbd60
https://pubmed.ncbi.nlm.nih.gov/16519965

Zobrazit plný text záznamu

Distinctive properties of the 5'-untranslated region of human hsp70 mRNA

Autor: Daria Sizova, Dmitri S. Ivanov, M. P. Rubtsova, Vladimir S. Prassolov, Ivan N. Shatsky, Sergei E. Dmitriev

Publikováno v: The Journal of biological chemistry. 278(25)

A relaxed cap-dependence of translation of the mRNA-encoding mammalian heat shock protein Hsp70 may suggest that its 5'-untranslated region (UTR) possesses an internal ribosome entry site (IRES). In this study, this possibility has been tested in tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e2a2aebcee876fd76f8c5f4a143685
https://pubmed.ncbi.nlm.nih.gov/12682055

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání