Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Daria N. Shalaeva"'
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1346 (2022)
To clarify the obscure hydrolysis mechanism of ubiquitous P-loop-fold nucleoside triphosphatases (Walker NTPases), we analysed the structures of 3136 catalytic sites with bound Mg-NTP complexes or their analogues. Our results are presented in two art
Externí odkaz:
https://doaj.org/article/fd4eb8263e484062bc9e4f10ac24a55d
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1345 (2022)
The P-loop fold nucleoside triphosphate (NTP) hydrolases (also known as Walker NTPases) function as ATPases, GTPases, and ATP synthases, are often of medical importance, and represent one of the largest and evolutionarily oldest families of enzymes.
Externí odkaz:
https://doaj.org/article/d8abcd88de984485b7e8078874551d10
Autor:
Daria N Shalaeva, Dmitry A Cherepanov, Michael Y Galperin, Andrey V Golovin, Armen Y Mulkidjanian
Publikováno v:
eLife, Vol 7 (2018)
The ubiquitous P-loop fold nucleoside triphosphatases (NTPases) are typically activated by an arginine or lysine ‘finger’. Some of the apparently ancestral NTPases are, instead, activated by potassium ions. To clarify the activation mechanism, we
Externí odkaz:
https://doaj.org/article/209f25b647a34169a4466463c89b1b5a
Although P-loop fold nucleoside triphosphatases (also known as Walker NTPases) are ubiquitous, their catalytic mechanism remains obscure. Based on a comparative structural analysis of 3136 Mg-NTP-containing catalytic sites, we propose a common scheme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ebad826ce72500a58e28465efdbdc2
https://doi.org/10.1101/2022.06.23.497301
https://doi.org/10.1101/2022.06.23.497301
Autor:
Dmitry A. Cherepanov, I. M. Bushmakin, J. D. Belyaeva, Maria I. Kozlova, Daria N. Shalaeva, Armen Y. Mulkidjanian, Daria V. Dibrova
Publikováno v:
Biochemistry (Moscow). 85:1518-1542
In 1986, Vladimir Skulachev and his colleagues coined the term "Sodium World" for the group of diverse organisms with sodium (Na)-based bioenergetics. Albeit only few such organisms had been discovered by that time, the authors insightfully noted tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbfebf2f5e1b3592d4a9c6503f34400
https://doi.org/10.1134/s0006297920120056
https://doi.org/10.1134/s0006297920120056
Autor:
Ilya M. Bushmakin, Daria N. Shalaeva, Daria V. Dibrova, Maria I. Kozlova, Olesya I. Klimchuk, Armen Y. Mulkidjanian, Dmitry A. Cherepanov, Julia D. Belyaeva
Publikováno v:
Proceedings of the 3rd International Conference in celebration of the 85th birthday of professor V.P. Skulachev. Abstract Book.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::644b2bfabfdcc9ed4505f3dbc22572b8
https://doi.org/10.30826/homosapiens-2020-06
https://doi.org/10.30826/homosapiens-2020-06
Autor:
Michael Y. Galperin, Gert Vriend, Daria N. Shalaeva, Armen Y. Mulkidjanian, Dmitry A. Cherepanov
The human genome contains about 700 genes of G protein-coupled receptors (GPCRs) of class A; these seven-helical membrane proteins are the targets of almost half of all known drugs. In the middle of the helix bundle, crystal structures revealed a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86de47b40c10b0edb5d2333e7f689932
P-loop nucleoside triphosphatases (NTPases) share common Walker A (P-loop) and Walker B sequence motifs and depend on activating moieties (Arg or Lys fingers or a K+ion). In search for a common catalytic mechanism, we combined structure comparisons o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32af48702680bf1b1cb706437d81220
Publikováno v:
MOLECULAR PHYLOGENETICS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92d8bb3766270a9c46ef34e5b182fd62
https://doi.org/10.30826/molphy2018-09
https://doi.org/10.30826/molphy2018-09