Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daria Monaldi"'
Autor:
Daria, Monaldi, Dante, Rotili, Julien, Lancelot, Martin, Marek, Nathalie, Wössner, Alessia, Lucidi, Daniela, Tomaselli, Elizabeth, Ramos-Morales, Christophe, Romier, Raymond J, Pierce, Antonello, Mai, Manfred, Jung
Publikováno v:
Journal of medicinal chemistry. 62(19)
The only drug currently available for treatment of the neglected disease Schistosomiasis is Praziquantel, and the possible emergence of resistance makes research on novel therapeutic agents necessary and urgent. To this end, the targeting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ec21040e92d40996e35c3f07a830dd4
https://pubmed.ncbi.nlm.nih.gov/31496251
https://pubmed.ncbi.nlm.nih.gov/31496251
Autor:
Raymond J. Pierce, Nathalie Wössner, Christophe Romier, Elizabeth Ramos-Morales, Daria Monaldi, Antonello Mai, Dante Rotili, Manfred Jung, Alessia Lucidi, Julien Lancelot, Daniela Tomaselli, Martin Marek
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (19), pp.8733-8759. ⟨10.1021/acs.jmedchem.9b00638⟩
Journal of Medicinal Chemistry, 2019, 62 (19), pp.8733-8759. ⟨10.1021/acs.jmedchem.9b00638⟩
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (19), pp.8733-8759. ⟨10.1021/acs.jmedchem.9b00638⟩
Journal of Medicinal Chemistry, 2019, 62 (19), pp.8733-8759. ⟨10.1021/acs.jmedchem.9b00638⟩
The standard drug for treatment of the neglected disease Schistosomiasis is Praziquantel, and the possible emergence of resistance to this treatment makes the research on novel therapeutic agents necessary and urgent. To this end, the targeting of Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f590f6837f9fd9369c77a49ed274ed34
https://doi.org/10.26434/chemrxiv.7957544.v1
https://doi.org/10.26434/chemrxiv.7957544.v1
Autor:
Dina Robaa, Minoru Yoshida, Nathalie Wössner, Manfred Jung, Norio Kudo, Tobias Rumpf, Daria Monaldi, Matthias Schiedel
Publikováno v:
Chemical record (New York, N.Y.). 18(12)
Reversible lysine deacetylation is exerted by both zinc and NAD+ -dependent deacetylases. It is an important factor in epigenetic regulation and more generally in the posttranslational regulation of protein stability, association and activity. Some o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f04a013509ab957ac6e46c02718f9da
https://pubmed.ncbi.nlm.nih.gov/29931800
https://pubmed.ncbi.nlm.nih.gov/29931800
Autor:
Sören, Swyter, Matthias, Schiedel, Daria, Monaldi, Sándor, Szunyogh, Attila, Lehotzky, Tobias, Rumpf, Judit, Ovádi, Wolfgang, Sippl, Manfred, Jung
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1748)
Sirtuins are NAD(+)-dependent protein deacylases capable of cleaving off acetyl as well as other acyl groups from the ɛ-amino group of lysines in histones and other substrate proteins. They have been reported as promising drug targets, and thus modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::853b490fa0295dcbcd6c042ab0b77f01
https://pubmed.ncbi.nlm.nih.gov/29685963
https://pubmed.ncbi.nlm.nih.gov/29685963
Autor:
Sándor Szunyogh, Judit Ovádi, Wolfgang Sippl, Sören Swyter, Daria Monaldi, Tobias Rumpf, Attila Lehotzky, Manfred Jung, Matthias Schiedel
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 373:20170083
Sirtuins are NAD + -dependent protein deacylases capable of cleaving off acetyl as well as other acyl groups from the ɛ-amino group of lysines in histones and other substrate proteins. They have been reported as promising drug targets, and thus modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43e4d80dc58b85bec05a5f7ab1bcaba6
https://doi.org/10.1098/rstb.2017.0083
https://doi.org/10.1098/rstb.2017.0083
Autor:
Antonello Mai, Daria Monaldi, Donatella Labella, Roberto Cirilli, Bruna Saponara, Mario Varasi, Paola Vianello, Andrea Mattevi, Oronza A. Botrugno, Veronica Rodriguez, Paola Dessanti, Giovanni Ruoppolo, Giuseppe Ciossani, Biagina Marrocco, Mats Tilset, Sergio Valente, Saverio Minucci, Ciro Mercurio
The pure enantiomers of the N-(2-, 3-, and 4-(2-aminocyclopropyl)phenyl)benzamides hydrochlorides 11a-j were prepared and tested against LSD1 and MAO enzymes. The evaluation of the regioisomers 11a-j highlighted a net increase of the anti-LSD1 potenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2619021340ef053fdf0fa9b41160edb
http://hdl.handle.net/11573/781693
http://hdl.handle.net/11573/781693
Autor:
Robaa, Dina1, Monaldi, Daria2, Wössner, Nathalie2, Kudo, Norio3, Rumpf, Tobias4, Schiedel, Matthias5, Yoshida, Minoru3, Jung, Manfred2 manfred.jung@pharmazie.uni-freiburg.de
Publikováno v:
Chemical Record. Dec2018, Vol. 18 Issue 12, p1701-1707. 7p.