Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daria Leonidovna Ivanova"'
Publikováno v:
The Journal of Immunology. 208:122.28-122.28
T cells that express TCF1 display self-renewing capacity and are essential for the long-term T cell response during chronic infections and cancer. Due to their increased responsiveness to checkpoint blockade, TCF1+ T cells are recognized as promising
Publikováno v:
The Journal of Immunology. 206:102.02-102.02
T cells that express high levels of TCF1 display stem cell-like properties and give rise to effector-like cells that protect during chronic infections and cancer. Due to their increased responsiveness to checkpoint blockade, TCF1hi T cells are now re
Publikováno v:
The Journal of Immunology. 206:102.01-102.01
Protection from pathogens relies on both humoral (antibody-mediated) and cellular (T cell-mediated) responses. While infections robustly elicit both of these types of immunity, currently approved vaccine adjuvants largely fail to induce significant T
Publikováno v:
The Journal of Immunology. 204:169.12-169.12
Our lab has developed a subunit vaccination regimen that induces a highly robust T cell response. These vaccine-elicited CD8+ T cells (Tvac) are phenotypically, functionally and metabolically distinct from infection-elicited CD8+ T cells (Tinf). In c