Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Daret K. St Clair"'
Autor:
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsiu-Chuan Yen, Daret K. St Clair, Hiroko P. Indo, Hideyuki J. Majima
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 128 (2024)
Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed. In this study, two parameters, the calculated dipole moment (debye, D) and permeability co
Externí odkaz:
https://doaj.org/article/2f9fcb72f1c247bc85463ff752e569d2
Autor:
Sudha Sharma, Susmita Bhattarai, Hosne Ara, Grace Sun, Daret K. St Clair, Md Shenuarin Bhuiyan, Christopher Kevil, Megan N. Watts, Paari Dominic, Takahiko Shimizu, Kevin J. McCarthy, Hong Sun, Manikandan Panchatcharam, Sumitra Miriyala
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101740- (2020)
Electrophilic aldehyde (4-hydroxynonenal; 4-HNE), formed after lipid peroxidation, is a mediator of mitochondrial dysfunction and implicated in both the pathogenesis and the progression of cardiovascular disease. Manganese superoxide dismutase (MnSOD
Externí odkaz:
https://doaj.org/article/2e80799244c74b9aa7443b34abaa0a5a
Autor:
M. Paul Murphy, Tina L. Beckett, Qunxing Ding, Ela Patel, William R. Markesbery, Daret K. St Clair, Harry LeVine, III, Jeffrey N. Keller
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 3, Pp 301-311 (2007)
Amnestic mild cognitive impairment (MCI) appears to be a very early stage of Alzheimer’s disease (AD). The amyloid-β peptide (Aβ) is believed to be a possible substrate for AD, but little is currently known about Aβ alterations in MCI and how th
Externí odkaz:
https://doaj.org/article/6688d2293c004d928f99bd43b0d0182b
Autor:
Chontida Yarana, Hannah Thompson, Luksana Chaiswing, D. Allan Butterfield, Heidi Weiss, Subbarao Bondada, Sara Alhakeem, Suriyan Sukati, Daret K. St. Clair
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX
Externí odkaz:
https://doaj.org/article/98e908279b00465d8862dbf696cd086c
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots indicating PYGB, PYGM, and PYGL are tissue-specific protein. PYGB is highly expressed in heart and brain. PYGM is highly expressed in skeletal muscle. PYGL is highly expressed in liver. Vinculin and tubulin were used as appropriate posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fea728dcda5d7f7f893dd10818d90b
https://doi.org/10.1158/1078-0432.22464719.v1
https://doi.org/10.1158/1078-0432.22464719.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots display PYGB, PYGM, and PYGL expression. A. EVs from mice treated with saline or DOX. B. PYGB in EVs and heart tissues from wild-type or MnSOD Tg mice treated with saline or DOX. C. PYGB in EVs and heart tissues from mice treated with M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd61faf3794f9b6c272feb12687f7c3
https://doi.org/10.1158/1078-0432.22464710.v1
https://doi.org/10.1158/1078-0432.22464710.v1
Autor:
William H. St. Clair, Daret K. St. Clair, Jinfei Chen, Chi Wang, Teresa Noel, David Schnell, Luksana Chaiswing, Fang Fang Xu, Yong Xu, Xiaowei Wei
Cancer cells typically experience higher oxidative stress than normal cells, such that elevating pro-oxidant levels can trigger cancer cell death. Although pre-exposure to mild oxidative agents will sensitize cancer cells to radiation, this pre-expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3c22f3da7f1742c51643c3052409c5
https://doi.org/10.1158/0008-5472.c.6509657.v1
https://doi.org/10.1158/0008-5472.c.6509657.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Sucrose gradient isolation process for proteomics analysis. A. Diagram showing the process of EV isolation by sucrose gradient method. B. Western blots of EV markers, CD63 and CD81 of sucrose gradient fraction 1 to 5 (from the top to the bottom). C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52411e5ce76bed977078f08ddecb16d5
https://doi.org/10.1158/1078-0432.22464725.v1
https://doi.org/10.1158/1078-0432.22464725.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots confirming the existence of PYGB, PYGM, and PYGL in SAL_EVs and DOX_EVs after treatment with proteinase K. Cell lysate was used as a positive control for PYGB, PYGM and PYGL detection. IgG and albumin were measured as a reference for pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d262a9ef983c4733d0a56c262a0942
https://doi.org/10.1158/1078-0432.22464713
https://doi.org/10.1158/1078-0432.22464713
Autor:
William H. St. Clair, Daret K. St. Clair, Jinfei Chen, Chi Wang, Teresa Noel, David Schnell, Luksana Chaiswing, Fang Fang Xu, Yong Xu, Xiaowei Wei
After treatment with AA, the expression of RelB, Bcl-xL, and Bax in PC3 and PZ cells was quantified by western blots by RT-PCR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0956a0cb6d142edd0b7231fc58378fa8
https://doi.org/10.1158/0008-5472.22416815
https://doi.org/10.1158/0008-5472.22416815