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pro vyhledávání: '"Darel, Macdonald"'
Autor:
Darel, Macdonald, Darren D, Thomson, Anna, Johns, Adriana, Contreras Valenzuela, Jane M, Gilsenan, Kathryn M, Lord, Paul, Bowyer, David W, Denning, Nick D, Read, Michael J, Bromley
Publikováno v:
Macdonald, D, Thomson, D, Johns, A, Contreras Valenzuela, A, Gilsenan, J, Lord, K M, Bowyer, P, Denning, D W, Read, N & Bromley, M 2018, ' Inducible Cell Fusion Permits Use of Competitive Fitness Profiling in the Human Pathogenic Fungus Aspergillus fumigatus ', Antimicrobial Agents and Chemotherapy . https://doi.org/10.1128/AAC.01615-18
Antifungal agents directed against novel therapeutic targets are required for treating invasive, chronic, and allergic Aspergillus infections. Competitive fitness profiling technologies have been used in a number of bacterial and yeast systems to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c785e252c1a45c6e157c22b3a2e192d0
https://www.research.manchester.ac.uk/portal/en/publications/inducible-cell-fusion-permits-use-of-competitive-fitness-profiling-in-the-human-pathogenic-fungus-aspergillus-fumigatus(7a1a6275-0ef9-4d56-bb01-8248dae11926).html
https://www.research.manchester.ac.uk/portal/en/publications/inducible-cell-fusion-permits-use-of-competitive-fitness-profiling-in-the-human-pathogenic-fungus-aspergillus-fumigatus(7a1a6275-0ef9-4d56-bb01-8248dae11926).html
Autor:
Anna Johns, Peter Warn, Darel Macdonald, Sarah J. Kaye, Mike Birch, Michael Bromley, Jason David Oliver, Danny Tuckwell, Joanne Livermore
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 9, p e43559 (2012)
PLoS ONE, Vol 7, Iss 9, p e43559 (2012)
Dihydroxyacid dehydratase (DHAD) is a key enzyme in the branched-chain amino acid biosynthetic pathway that exists in a variety of organisms, including fungi, plants and bacteria, but not humans. In this study we identified four putative DHAD genes f