Prevalence of comorbidities with peanut allergy: results from two phase 3, randomized, double-blind, placebo-controlled trials (PALISADE and RAMSES)

Autor: Kirsten Beyer, Alan Goldsobel, Douglas Johnston, Noelle M. Griffin, Kari R. Brown, Trinh Pham, Andrea Vereda, Dareen Siri, George Du Toit

Publikováno v: World Allergy Organization Journal, Vol 13, Iss 8, Pp 100296- (2020)

Externí odkaz: https://doaj.org/article/3ab8aaa41d1d4a849dc238360eebe5d9

Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results

Autor: Robert J. Wood, Edmond S. Chan, Hey Chong, Paul J. Dowling, Allan Stillerman, Lynda C. Schneider, Stanley M. Fineman, Amarijit Cheema, Hugh A. Sampson, Edwin H. Kim, Timothée Bois, Todd D. Green, Ned Rupp, Terri F. Brown-Whitehorn, Sara Anvari, Dareen Siri, Roxanne C. Oriel, Jacqueline A. Pongracic, Sayantani B. Sindher, William E. Berger, Hemalini Mehta, Gordon Sussman, Erika G. Gonzalez-Reyes, Dianne E. Campbell, William H. Yang, Amy M. Scurlock, Sharon Chinthrajah, J. Andrew Bird, Lawrence Sher, Andrew J. MacGinnitie, Remi Gagnon, David Fleischer, Wayne G. Shreffler, Philippe Bégin, Bruce J. Lanser, Daniel Petroni

Publikováno v: The journal of allergy and clinical immunology. In practice. 10(7)

Background Treatment options for peanut allergy are limited. In previous clinical trials, epicutaneous immunotherapy with a patch containing 250-μg peanut protein (Viaskin™ Peanut 250 μg [VP250]) was well tolerated and statistically superior to p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e44848e8d76a75ea01e1c398fb42b9
https://pubmed.ncbi.nlm.nih.gov/35809991

AR101 Oral Immunotherapy for Peanut Allergy

Autor: Hey Chong, Antonella Muraro, Caroline Nilsson, Julie Wang, Jonathan Matz, Tara F. Carr, Andrea Vereda, Stephanie A. Leonard, Douglas T Johnston, Katharina Blumchen, Moshe Ben-Shoshan, Stanley Fineman, Frank C Hampel, Montserrat Fernandez-Rivas, Michael J Welch, José Manuel Zubeldia, Jay M. Portnoy, Carsten Bindslev-Jensen, Rima Rachid, Leon Greos, Vibha Sharma, Brian P. Vickery, Marina Tsoumani, Dareen Siri, Edwin H. Kim, Lyndon E Mansfield, A. Wesley Burks, J. Andrew Bird, Daniel C. Adelman, Ellen Sher, Robert A. Wood, Thomas B. Casale, Stephen A. Tilles, Annette Marcantonio, Hugh H Windom, Hanneke N G Oude Elberink, Stefan Zielen, Hemant P Sharma, Wayne G. Shreffler, Bruce J. Lanser, Amarjit Cheema, Ned Rupp, Stephen B Fritz, Stacie M. Jones, Allan Stillerman, Gordon Sussman, Frederick E Leickly, Stephen G Dilly, W. Carr, Jay A. Lieberman, Pooja Varshney, David Fleischer, Kirsten Beyer, William H. Yang, Jacqueline A. Pongracic, Morna J. Dorsey, George Du Toit, Jason A. Ohayon, Aikaterini Anagnostou, M Dolores Ibáñez, David K Jeong, Amal Assa'ad, Jonathan O'b Hourihane, Rita Kachru, Anthony E.J. Dubois, Christina E. Ciaccio, Rezi Zawadzki, Sharon Chinthrajah, Lawrence Sher, Georgiana M Sanders, Jonathan M. Spergel

Publikováno v: Vickery, B P, Vereda, A, Casale, T B, Beyer, K, Du Toit, G, Hourihane, J O, Jones, S M, Shreffler, W G, Marcantonio, A, Bindslev-Jensen, C & PALISADE Group of Clinical Investigators 2018, ' AR101 Oral Immunotherapy for Peanut Allergy ', The New England Journal of Medicine, vol. 379, no. 21, pp. 1991-2001 . https://doi.org/10.1056/NEJMoa1812856
New England Journal of Medicine, 379(21), 1991-2001. MASSACHUSETTS MEDICAL SOC

BACKGROUND: Peanut allergy, for which there are no approved treatment options, affects patients who are at risk for unpredictable and occasionally life-threatening allergic reactions.METHODS: In a phase 3 trial, we screened participants 4 to 55 years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07f9259ccb8f596e94cbcf8a87e2855
https://doi.org/10.1056/nejmoa1812856

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

Autor: William W Busse, Eugene R Bleecker, J Mark FitzGerald, Gary T Ferguson, Peter Barker, Stephanie Sproule, Richard F Olsson, Ubaldo J Martin, Mitchell Goldman, Anahí Yañez, Marcelo Fernández, Alberto Tolcachier, Juan Belloni, Jorge Taborda, Maria De Salvo, Jorge Maspero, Carlos Victorio, Miguel Chirino Navarta, Monica Grilli, Pablo Rodríguez, María Otaola, Víctor Cambursano, Patricia Malamud, Ana Stok, German Arce, Osiris Roza, Fernando Scherbovsky, Pedro Elias, Maria Salazan Saez, Matthew Peters, Martin Phillips, John Upham, Peter Gibson, Francis Thien, Jo Douglass, Paul Thomas, Philip Bardin, Dimitar Sajkov, Mark Hew, David Langton, Andreia Pez, Carlos Fritscher, Jorge Hetzel, Waldo Mattos, Rafael Stelmach, Martti Antila, Ana Luisa Fernandes, Hristo Metev, Yavor Ivanov, Aneliya Bogdanova, Ana Dancheva Markova, Marinka Peneva, Rumyana Veselinova, Tatyana Petkova, Vanushka Petrova, Elena Shopova, Yuliya Ivanova, Rumyana Yotsova, Ginka Kirkova, Galina Petrova, Svetoslav Dachev, Kostadinka Sotirova, Mariyana Stoyanova, Oleg Yakov, Vanya Ilieva-Fartunova, Catherine Lemiere, Michel Laviolette, William Yang, Bonavuth Pek, William Patrick Killorn, Claude Poirier, Guy Chouinard, Lyle Melenka, Richard Leigh, Parameswaran Nair, Delbert Dorscheid, James Martin, Juana Pavie, Andres Rosenblut, Claudia Cartagena, Carlos Quilodran, Silvia Muñoz, Ivana Malkusova, Josef Veverka, Stanislav Holub, Jaroslav Mares, Radovan Kozel, Daniela Kopecka, Vladimir Zindr, Pavel Cerva, Pascal Chanez, Arnaud Bourdin, Gilles Devouassoux, Camille Taille, Frédéric De Blay, Francois Goupil, Christophe Leroyer, Delphine Gourcerol, Toufik Didi, Alain Didier, Gilles Garcia, Philippe Bonniaud, Riazate Rossanaly Vasram, Marek Lommatzsch, Ulf Harnest, Anneliese Linnhoff, Claus Keller, Gerhard Hoheisel, Karin Förster, Thomas Schultz, Isabelle Schenkenberger, Joachim Kirschner, Tibor Schmoller, Stefan Zielen, Marc Kornmann, Ekkehard Beck, Lutz Volgmann, Rolf Dichmann, Axel Overlack, Jörg Winkler, Petra Mikloweit, Sabine Ballenberger, Mathias Rolke, Stephanie Korn, Helmut Pabel, Martin Hoffmann, Jan Feimer, Klaus Rabe, Regina Deckelmann, Tobias Welte, Hiroyuki Ohbayashi, Soichiro Hozawa, Terufumi Shimoda, Makoto Yoshida, Toshikazu Nagakura, Tadashi Kamei, Yasuyuki Sano, Shinichiro Kagami, Hisaho Takahashi, Michiko Haida, Goro Kimura, Hiroyuki Nakamura, Yasuo To, Masaharu Shinkai, Tadasuke Shimokawaji, Makoto Kudo, Noriharu Shijyubo, Takao Tochigi, Motokazu Kato, Akihiko Tanaka, Yasuhiro Gon, Norihisa Sasaki, Tetsuro Ohdaira, Chiharu Omori, Toshiki Takahashi, Satomi Takeuchi, Kiyotaka Nakajima, Hironi Makita, Masahiro Kaneko, Kenjiro Furuta, Masami Taniguchi, Yoshito Inobe, Hiroshi Miki, Yoichi Nakamura, Naoki Miyazawa, Shuichi Yano, Masayuki Iijima, Tsuyoshi Yamato, Javier Diaz, Alberto Matsuno, Efrain Felix, Alfredo Guerreros, Alejandro Daly, Fernando Rodriguez Chariarse, Danilo Salazar, Socorro Castro, William Chavez, Rolando Estrella, Teresita Aquino, Tito Atienza, Ronnie Samoro, Marie Grace Dawn Isidro, Piotr Kuna, Adam Antczak, Michał Bednarek, Danuta Mądra-Rogacka, Teresa Hofman, Marek Jutel, Ewa Pisarczyk-Bogacka, Agata Kot, Robert Mróz, Małgorzata Czupryńska-Borkowska, Małgorzata Żurowska-Gębala, Andrzej Dyczek, Grażyna Jasieniak-Pinis, Piotr Wojnowski, Ewa Trębas-Pietraś, Małgorzata Dobryniewska, Marcin Stobiecki, Marzenna Tarnowska-Matusiak, Alina Magner, Andrzej Kolczyński, Tomasz Kachel, Zbigniew Bartuzi, Bernadetta Majorek-Olechowska, Paweł Śliwiński, Violetta Balicka, Elżbieta Hajoł, Jacek Stachera, Marta Rachel, Marek Michnar, Jarosław Tałałaj, Ewa Springer, Piotr Napora, Tomasz Grzelewski, Renata Bijata-Bronisz, Anna Świderska, Grzegorz Mincewicz, Zbigniew Sankowski, Tomasz Fijołek, Artur Kwaśniewski, Joanna Jerzyńska, Jerzy Cygler, Ryszard Olesiejuk, Iwona Von Steiner, Wojciech Machowiak, Krzysztof Filipek, Piotr Piskorz, Ewa Uhryn, Marita Nittner-Marszalska, Elżbieta Rybicka-Liszewska, Anna Bodzenta-Łukaszyk, Marta Chełmińska, Izabella Krupa-Borek, Wojciech Skucha, Anna Płoszczuk, Traian Mihaescu, Ioan Dorin Petrui, Angelica Savu, Ghiulten Apti, Claudia Toma, Ana Trailescu, Sergei Sokurenko, Vasiliy Trofimov, Igor Leshchenko, Natalia Shaporova, Inna Ilyashevich, Irina Stitsenko, Alexander Vizel, Yulia Ilkovich, Dmitrii Tikhanov, Svetlana Goncharova, Andrey Ezhov, Galina Ignatova, Nadezhda Izmozherova, Nadezhda Berdnikova, Ludmila Goryachkina, Veronika Popova, Laura Bolieva, Andrey Rebrov, Vladimir Nosov, Olga Magnitskaya, Sergey Nedogoda, Vladimir Abrosimov, Artem Molotkov, Galina Reshedko, Mikhail Smirnov, Marina Osipenko, Elena Pavlysh, Svetlana Myasoedova, Liudmila Lenskaya, Valery Chistyakov, Elena Vishneva, Liliya Uon, Anna Zateyschikova, Svetlana Laleko, Tatiana Pak, Axel Bruning, Visvakuren Naidoo, Jeevren Reddy, Richard Van Zyl Smit, Hae-Sim Park, Young Joo Cho, Sang-Heon Cho, Sang Haak Lee, Byung Jae Lee, Ju Sang Kim, You Sook Cho, Choon-Sik Park, Mi-Kyeong Kim, Young-Il Koh, Joo-Hee Kim, Sook Young Lee, Sang Pyo Lee, Jung Won Park, Kwang Ha Yoo, Hyoungkyu Yoon, Jaechun Lee, Gyu-Young Hur, Soo Keol Lee, HeeKyoo Kim, David Ramos Barbón, Elena Laffond Yges, Eva Martínez Moragón, Miguel Arias Guillen, Alberto Saura Vinuesa, Fernando Sánchez-Toril López, José Luis Velasco Garrido, Borja García-Cosio Piqueras, Luis Pérez de Llano, Antonio Luis Valero Santiago, Myriam Calle Rubio, Leif Bjermer, Bo Lundbäck, Bilun Gemicioglu, Sevim Bavbek, Dane Ediger, Munevver Erdinc, Ismail Hanta, Sibel Nayci, Sibel Arinc, Liudmyla Iashyna, Yuriy Mostovoy, Mykola Ostrovskyy, Lesia Kuryk, Ivan Lemko, Tetyana Ospanova, Liubov Moskalenko, Oleksii Korzh, Viktor Blazhko, Olena Krakhmalova, Liliia Romaniuk, Yevgeniya Dytyatkovs'ka, Oleh Yakovenko, Volodymyr Gavrysyuk, Hassan Burhan, Dinesh Saralaya, Stephen Scott, Alyn Morice, Ewart Jackson-Voyzey, Thida Win, Shuab Nasser, Richard Harrison, Rekha Chaudhuri, Monica Nordstrom, Pradip De, Matthew Masoli, Adel Mansur, Anthony Gunstone, Robert Niven, Timothy Harrison, Suresh Babu, Subodh Bhuchar, Shahrukh Kureishy, John Zwetchkenbaum, Lawrence Kaplan, Eugene Bleecker, Santiago Reyes, Faisal Fakih, Marvin Heuer, Ryan Klein, Michael Marcus, Iftikhar Hussain, Tonny Tanus, Hengameh Raissy, Sady Alpizar, Hector Rodriguez, Gerald Gleich, Tracy Bridges, Joe Pouzar, Gary Steven, Jonathan Matz, Shana Krstevska, Dama Ziworitin, Adolfo Kaplan, James Sublett, James DeAngelo, Amy Darter, John Agaiby, John Hagan, Enrique Davis, Dareen Siri, Charlene Mcevoy, Chrisette Dharma, Najmuddin Karimjee, Steven Kelsen, Manuel Frade, Amy Silverthorn, Joel Kline, Francis Averill, Jose Ruiz, Emory Robinette, Zeeshan Shaikh, Carlos Aguilar, William Nish, German Alvarez, Younus Ismail, Purvi Parikh, Mila Leong, Dennis Murphy, Francisco Garcia, Alan Goldsobel, Antonio Blanco, Edward Campbell, Guido Perez, Geoffrey Chupp, Toby Bates, Vandely Perez, Sally Wenzel, Kartik Shenoy, Rohit Katial, David Bernstein, Neil Parikh, William Sims, Gary Ferguson, David Pham, Anu George, Richard Beasley, Gilberto Perez, Robert Garver, Miriam Garcia-Portela, Stephen Wong, Weily Soong, Richard Guillot, Golda Hudes, Ahmed Arif, Josefa Binker, Manuel Villareal, Ulrike Ziegner, Joseph Ojile, Sanjeev Goswami, Carlos Piniella, Ilia Segal, Heidi Zafra, Mitchell Lee, Martha Tarpay, John Panuto, Rajan Merchant, Peter Springsteen, Timothy Scialla, Paul Shapero, Karen Allen, Mark Moss, Humberto Cruz, Jeffrey Rumbyrt, Amy Boyd, Robert Nathan, Jonathan Bernstein, Joshua Jacobs, Elliot Ginchansky, Janice Johnston, Barbara Baxter, Thomas Johnson II, Stephen Apaliski, Clinton Corder, David Fuentes, Joseph Diaz, Chau Ngo, Lan Le

Publikováno v: Lancet Respiratory medicine
Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59. ⟨10.1016/S2213-2600(18)30406-5⟩
Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59
The Lancet Respiratory Medicine
The Lancet Respiratory Medicine, 2019, 7 (1), pp.46-59. ⟨10.1016/S2213-2600(18)30406-5⟩

Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal antibody that has been shown to safely reduce exacerbations and improve lung function for patients with asthma. We assessed the long-term safety and efficacy of benralizumab f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0807d2067546999db31f931325a88a
https://hal.univ-brest.fr/hal-02052347

P307 PATIENT EXPERIENCES WITH EPICUTANEOUS IMMUNOTHERAPY FOR PEANUT ALLERGY IN OLFUS-VIPES & REALISE TRIALS: QUALITATIVE STUDIES

Autor: J. Chalil, Amarjit Cheema, Kari C. Nadeau, Terri F. Brown-Whitehorn, Daniel Petroni, Jacqueline A. Pongracic, Gordon Sussman, B. Arnould, Dareen Siri, B. Tugaut

Publikováno v: Annals of Allergy, Asthma & Immunology. 125:S42

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33455c033518e40ded455f4db499edb0
https://doi.org/10.1016/j.anai.2020.08.143