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pro vyhledávání: '"Darcy L Morse"'
Autor:
Sharon Kim, Charles Boone, Darcy L Morse, Anastasia Baryshnikova, Stacie E Dodgson, Angelika Amon, Michael Costanzo, Chris A. Kaiser
Aneuploidy, an unbalanced karyotype in which one or more chromosomes are present in excess or reduced copy number, causes an array of known phenotypes including proteotoxicity, genomic instability, and slowed proliferation. However, the molecular con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6c6cb477f07bde752fbaac7bd25546
https://europepmc.org/articles/PMC4905547/
https://europepmc.org/articles/PMC4905547/
Autor:
Jason Moffat, Chris A. Kaiser, Charles Boone, Christopher J. Roberts, Nevan J. Krogan, Miles Trochesset, Xueqi Yang, Gordon Chua, Jennifer Haynes, Andres Lopez, Nicholas Mitsakakis, Shawna L. Hiley, Wen-Tao Peng, Armaity P. Davierwala, Brenda J. Andrews, Jörg Grigull, Jeff Pootoolal, Darcy L Morse, Timothy P. Hughes, Jack Greenblatt, Sanie Mnaimneh, Wen Zhang, Zhijian Li, Quaid Morris
Publikováno v:
Cell. 118(1)
Nearly 20% of yeast genes are required for viability, hindering genetic analysis with knockouts. We created promoter-shutoff strains for over two-thirds of all essential yeast genes and subjected them to morphological analysis, size profiling, drug s