Zobrazeno 1 - 10
of 476
pro vyhledávání: '"Darby, G."'
Autor:
Rhodes, L.E., Darby, G., Massey, Karen A., Clarke, K.A., Dew, T.P., Farrar, M.D., Bennett, S., Watson, R.E.B., Williamson, G., Nicolaou, Anna
Green tea catechins (GTC) reduce UV radiation (UVR)-induced inflammation in experimental models, but human studies are scarce and their cutaneous bioavailability and mechanism of photoprotection are unknown. We aimed to examine oral GTC cutaneous upt
Externí odkaz:
http://hdl.handle.net/10454/7251
Autor:
Kyle R. Smith, Somnath Paul, Qiwen Dong, Orchi Anannya, Darby G. Oldenburg, J. Craig Forrest, Kevin M. McBride, Laurie T. Krug
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA repair. Mammalian uracil-DNA glycosylases (UNG) excise deleterious uracil residues from
Externí odkaz:
https://doaj.org/article/db2ec48fefc6463ba061614bbbfb2d73
Akademický článek
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Publikováno v:
Science, 2017 Jun . 356(6345), 1342-1342.
Externí odkaz:
https://www.jstor.org/stable/26399313
Autor:
Samson T. Jacob, Sanjeev Redkar, Pasit Phiasivongsa, Darby G. Brooke, Swarna A. Gamage, William A. Denny, Kalpana Ghoshal, Jharna Datta
Supplementary Methods and Figure Legends 1-2 from A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3799b309d50b587234700ace1d5b600a
https://doi.org/10.1158/0008-5472.22377986.v1
https://doi.org/10.1158/0008-5472.22377986.v1
Autor:
Samson T. Jacob, Sanjeev Redkar, Pasit Phiasivongsa, Darby G. Brooke, Swarna A. Gamage, William A. Denny, Kalpana Ghoshal, Jharna Datta
Supplementary Figures 1-2 from A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb8f2680f40d7788cefd637c2cc0cb9
https://doi.org/10.1158/0008-5472.22377989.v1
https://doi.org/10.1158/0008-5472.22377989.v1
Autor:
Qiwen Dong, Kyle R. Smith, Darby G. Oldenburg, Maxwell Shapiro, William R. Schutt, Laraib Malik, Joshua B. Plummer, Yunxiang Mu, Thomas MacCarthy, Douglas W. White, Kevin M. McBride, Laurie T. Krug
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Misincorporation of uracil or spontaneous cytidine deamination is a common mutagenic insult to DNA. Herpesviruses encode a viral uracil-DNA glycosylase (vUNG) and a viral dUTPase (vDUT), each with enzymatic and nonenzymatic functions. Howeve
Externí odkaz:
https://doaj.org/article/e0bb07380d1b4f38bdcc807e729ffc60
Autor:
Nick D Van Skike, Nana K Minkah, Chad H Hogan, Gary Wu, Peter T Benziger, Darby G Oldenburg, Mehmet Kara, Deborah M Kim-Holzapfel, Douglas W White, Scott A Tibbetts, Jarrod B French, Laurie T Krug
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007319 (2018)
[This corrects the article DOI: 10.1371/journal.ppat.1006843.].
Externí odkaz:
https://doaj.org/article/d55fa571fd46423cac168acc91f4ab9f
Autor:
Nick D Van Skike, Nana K Minkah, Chad H Hogan, Gary Wu, Peter T Benziger, Darby G Oldenburg, Mehmet Kara, Deborah M Kim-Holzapfel, Douglas W White, Scott A Tibbetts, Jarrod B French, Laurie T Krug
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006843 (2018)
Gammaherpesviruses encode proteins with homology to the cellular purine metabolic enzyme formyl-glycinamide-phosphoribosyl-amidotransferase (FGARAT), but the role of these viral FGARATs (vFGARATs) in the pathogenesis of a natural host has not been in
Externí odkaz:
https://doaj.org/article/b1341950bb304c61a8fd0dcb56a91ad8
Autor:
Eduardo Salinas, Arundhati Gupta, Jeffrey M Sifford, Darby G Oldenburg, Douglas W White, J Craig Forrest
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006865 (2018)
Gammaherpesvirus (GHV) pathogenesis is a complex process that involves productive viral replication, dissemination to tissues that harbor lifelong latent infection, and reactivation from latency back into a productive replication cycle. Traditional l
Externí odkaz:
https://doaj.org/article/f04c5933ba0a4fb7b07262c6c1cc967b