Angiotensin II evokes angiogenic signals within skeletal muscle through co-ordinated effects on skeletal myocytes and endothelial cells.

Autor: Jennifer L Gorman, Sammy T K Liu, Dara Slopack, Khashayar Shariati, Adam Hasanee, Sara Olenich, I Mark Olfert, Tara L Haas

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85537 (2014)

Skeletal muscle overload induces the expression of angiogenic factors such as vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMP)-2, leading to new capillary growth. We found that the overload-induced increase in angiogenesis

Externí odkaz: https://doaj.org/article/f369d4cc88394bebb52a07344e33ae71

Forkhead BoxO transcription factors restrain exercise-induced angiogenesis

Autor: Dara, Slopack, Emilie, Roudier, Sammy T K, Liu, Emmanuel, Nwadozi, Olivier, Birot, Tara L, Haas

Publikováno v: The Journal of physiology. 592(18)

The physiological process of exercise-induced angiogenesis involves the orchestrated upregulation of angiogenic factors together with repression of angiostatic factors. The Forkhead Box 'O' (FoxO) transcription factors promote an angiostatic environm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c5735142f8f9772ff61eeca2f154572
https://pubmed.ncbi.nlm.nih.gov/25630258

Novel perspective: exercise training stimulus triggers the expression of the oncoprotein human double minute-2 in human skeletal muscle

Autor: Olivier Birot, Fares Gouzi, Dara Slopack, Julian Aiken, Tara L. Haas, Maurice Hayot, Thomas Gustafsson, Jacques Mercier, Emilie Roudier

Publikováno v: Physiological Reports
Physiological Reports, Wiley, 2013, 1 (2), pp.e00028. ⟨10.1002/phy2.28⟩
Physiological Reports, 2013, 1 (2), pp.e00028. ⟨10.1002/phy2.28⟩

High expression levels of human double minute-2 (Hdm2) are often associated with increased risk of cancer. Hdm2 is well established as an oncoprotein exerting various tumorigenic effects. Conversely, the physiological functions of Hdm2 in nontumor ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b616b9832d4d1f02b1e60f31141b43ff
https://www.hal.inserm.fr/inserm-02398238

Is Human Double Minute‐2 a new marker of angiogenesis in exercised human skeletal muscle?

Autor: Julian Aiken, Tara L. Haas, Fares Gouzi, Jacques Mercier, Maurice Hayot, Thomas Gustafsson, Olivier Birot, Dara Slopack, Emilie Roudier

Publikováno v: The FASEB Journal. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce909dd650acf3d4593e229a415dd879
https://doi.org/10.1096/fasebj.27.1_supplement.688.1