Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Dara S Manoach"'
Autor:
Jun Wang, Chenguang Jiang, Zhenglin Guo, Sinéad Chapman, Nataliia Kozhemiako, Dimitrios Mylonas, Yi Su, Lin Zhou, Lu Shen, the GRINS Consortium, Shengying Qin, Michael Murphy, Shuping Tan, Dara S. Manoach, Robert Stickgold, Hailiang Huang, Zhenhe Zhou, Shaun M. Purcell, Meihua Hall, Steven E. Hyman, Jen Q. Pan
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Objective and quantifiable markers are crucial for developing novel therapeutics for mental disorders by 1) stratifying clinically similar patients with different underlying neurobiological deficits and 2) objectively tracking dis
Externí odkaz:
https://doaj.org/article/1c8a4623f61849f195c5f621c2c0a0aa
Autor:
Dara S Manoach, Charmaine eDemanuele, Erin J. Wamsley, Mark eVangel, Debra M Montrose, Jean eMiewald, David eKupfer, Daniel eBuysse, Robert eStickgold, Matcheri S Keshavan
Publikováno v:
Frontiers in Human Neuroscience, Vol 8 (2014)
Introduction: Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether antipsychotic-naïve early cou
Externí odkaz:
https://doaj.org/article/58277adcfcbe4096a6e767e857fe8a40
Autor:
Yigal Agam, Mark Vangel, Joshua L Roffman, Patience J Gallagher, Jonathan Chaponis, Stephen Haddad, Donald C Goff, Jennifer L Greenberg, Sabine Wilhelm, Jordan W Smoller, Dara S Manoach
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101784 (2014)
Neuroimaging studies reliably identify two markers of error commission: the error-related negativity (ERN), an event-related potential, and functional MRI activation of the dorsal anterior cingulate cortex (dACC). While theorized to reflect the same
Externí odkaz:
https://doaj.org/article/bcb8ef10f6a541fbbc499d12b9d79290
Autor:
Dara S Manoach, Yigal eAgam
Publikováno v:
Frontiers in Human Neuroscience, Vol 7 (2013)
Learning from errors is fundamental to adaptive human behavior. It requires detecting errors, evaluating what went wrong, and adjusting behavior accordingly. These dynamic adjustments are at the heart of behavioral flexibility and accumulating eviden
Externí odkaz:
https://doaj.org/article/4af25da5082346dab68e81d5e1cd38e2
Autor:
Esther Walton, Daniel Geisler, Johanna Hass, Jingyu Liu, Jessica Turner, Anastasia Yendiki, Michael N Smolka, Beng-Choon Ho, Dara S Manoach, Randy L Gollub, Veit Roessner, Vince D Calhoun, Stefan Ehrlich
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76815 (2013)
The neural mechanisms underlying genetic risk for schizophrenia, a highly heritable psychiatric condition, are still under investigation. New schizophrenia risk genes discovered through genome-wide association studies (GWAS), such as neurogranin (NRG
Externí odkaz:
https://doaj.org/article/f10acb323e0242a2af7a568cc9f56154
Autor:
Yigal Agam, Caitlin Carey, Jason J S Barton, Kara A Dyckman, Adrian K C Lee, Mark Vangel, Dara S Manoach
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73692 (2013)
The ability to dynamically and rapidly adjust task performance based on its outcome is fundamental to adaptive, flexible behavior. Over trials of a task, responses speed up until an error is committed and after the error responses slow down. These dy
Externí odkaz:
https://doaj.org/article/73f8da095a794c599a1042e4f146b01d
Autor:
Hao He, Jing Sui, Qingbao Yu, Jessica A Turner, Beng-Choon Ho, Scott R Sponheim, Dara S Manoach, Vincent P Clark, Vince D Calhoun
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38195 (2012)
Impairment of working memory (WM) performance in schizophrenia patients (SZ) is well-established. Compared to healthy controls (HC), SZ patients show aberrant blood oxygen level dependent (BOLD) activations and disrupted functional connectivity durin
Externí odkaz:
https://doaj.org/article/c67aaabe65b449a99645aa326b223872
Autor:
Joshua L Roffman, Adam Z Nitenson, Yigal Agam, Marlisa Isom, Jesse S Friedman, Kara A Dyckman, David G Brohawn, Jordan W Smoller, Donald C Goff, Dara S Manoach
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25253 (2011)
Responding to errors is a critical first step in learning from mistakes, a process that is abnormal in schizophrenia. To gain insight into the neural and molecular mechanisms of error processing, we used functional MRI to examine effects of a genetic
Externí odkaz:
https://doaj.org/article/a53ce123cb8740fb8c1a1de7d661d0dd
Autor:
Dara S Manoach, Robert Stickgold
Publikováno v:
Frontiers in Human Neuroscience, Vol 3 (2009)
Although disturbed sleep is a prominent feature of schizophrenia, its relation to the pathophysiology, signs, and symptoms of schizophrenia remains poorly understood. Sleep disturbances are well known to impair cognition in healthy individuals. Yet,
Externí odkaz:
https://doaj.org/article/3e7672e2b957489aaff71656ab0ed473
Autor:
Bengi Baran, Quynh Trang Huong Nguyen, Dimitrios Mylonas, Susan L. Santangelo, Dara S. Manoach
Publikováno v:
Autism Research. 16:271-279
There is converging evidence that abnormal thalamocortical interactions contribute to attention deficits and sensory sensitivities in autism spectrum disorder (ASD). However, previous functional MRI studies of thalamocortical connectivity in ASD have