Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dara Russell"'
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Mycobacterium abscessus infections are increasing worldwide. Current drug regimens are largely ineffective, yet the current development pipeline for M. abscessus is alarmingly sparse. Traditional discovery efforts for M. abscessus assess the capabili
Externí odkaz:
https://doaj.org/article/437e9331002d42c39a0781cd0f871487
Autor:
Catherine Shelton, Matthew McNeil, Renee Allen, Lindsay Flint, Dara Russell, Bryan Berube, Aaron Korkegian, Yulia Ovechkina, Tanya Parish
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
We previously identified a series of triazolopyrimidines with antitubercular activity. We determined that Mycobacterium tuberculosis strains with mutations in QcrB, a subunit of the cytochrome bcc-aa3 supercomplex, were resistant.
Autor:
Dara Russell, Lindsay Flint, Catherine Shelton, Bryan J. Berube, Matthew B. McNeil, Tanya Parish, Aaron Korkegian, Yulia Ovechkina
We previously identified a series of triazolopyrimidines with anti-tubercular activity. We determined that Mycobacterium tuberculosis strains with mutations in a component of the cytochrome bc1 system (QcrB) were resistant to the series. A cytochrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e65c5b71c08a88b1126fc2e40deb397f
https://doi.org/10.1101/2021.10.18.464924
https://doi.org/10.1101/2021.10.18.464924
Autor:
Bryan J, Berube, Dara, Russell, Lina, Castro, Seoung-Ryoung, Choi, Prabagaran, Narayanasamy, Tanya, Parish
Publikováno v:
Antimicrobial Agents and Chemotherapy
Mycobacterium tuberculosis is the leading cause of morbidity and death resulting from infectious disease worldwide. The incredible disease burden, combined with the long course of drug treatment and an increasing incidence of antimicrobial resistance