Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Dara L. Aisner"'
Autor:
Tejas Patil, MD, Alyse Staley, MS, Yunan Nie, MD, Mandy Sakamoto, MD, Margaret Stalker, MD, James M. Jurica, MD, MBA, Kenna Koehler, BA, Amanda Cass, PharmD, Halle Kuykendall, BA, Emily Schmitt, MS, Emma Filar, BA, Evelina Reventaite, MS, Kurt D. Davies, PhD, Hala Nijmeh, PhD, Mary Haag, PhD, Benjamin A. Yoder, PharmD, Paul A. Bunn, MD, Erin L. Schenk, MD, PhD, Dara L. Aisner, MD, PhD, Wade T. Iams, MD, Melina E. Marmarelis, MD, D. Ross Camidge, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 2, Pp 100637- (2024)
Introduction: Acquired MET gene amplification, MET exon 14 skip mutations, or MET fusions can emerge as resistance mechanisms to tyrosine kinase inhibitors (TKIs) in patients with lung cancer. The efficacy and safety of combining MET TKIs (such as cr
Externí odkaz:
https://doaj.org/article/63d7bcf67c604305b7273bb565a9b37b
Autor:
Katherine Priest, Anh Le, Amanuail Gebregzabheir, Hala Nijmeh, Gregory B. Reis, Melanie Mandell, Kurtis D. Davies, Carolyn Lawrence, Emily O’Donnell, Robert C. Doebele, Liming Bao, Dara L. Aisner, Erin L. Schenk
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Patients with metastatic NSCLC bearing a ROS1 gene fusion usually experience prolonged disease control with ROS1-targeting tyrosine kinase inhibitors (TKI), but significant clinical heterogeneity exists in part due to the presence of co-occu
Externí odkaz:
https://doaj.org/article/d06abc523d8e46278ad3f301b11a80b8
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Pemetrexed (used as a platinum doublet or as a maintenance regimen) is an established therapy for patients with advanced non-squamous non-small-cell lung cancer (NSCLC). In addition, certain gene rearrangements (e.g., ALK, ROS1, RET) appear to especi
Externí odkaz:
https://doaj.org/article/587e53c2c34a47079facfc26c57b9961
Autor:
Roy S. Herbst, Dara L. Aisner, Joshua R. Sonett, Andrew T. Turk, Joshua L. Weintraub, Neal I. Lindeman
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
For patients with advanced non–small cell lung cancer, genomic profiling of tumors to identify potentially targetable alterations and thereby inform treatment selection is now part of standard care. While molecular analyses are primarily focused on
Externí odkaz:
https://doaj.org/article/812b166817254889a7a4f9f80084a0a8
An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity
Autor:
Xiaoming Yi, Dennis M. White, Dara L. Aisner, Joseph A. Baur, Woodring E. Wright, Jerry W. Shay
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 5, Pp 433-440 (2000)
Telomerase, a cellular reverse transcriptase, adds telomeric repeats to chromosome ends. In normal human somatic cells, telomerase is repressed and telomeres progressively shorten, leading to proliferative senescence. Introduction of the telomerase (
Externí odkaz:
https://doaj.org/article/128e2629cdbb4d9a9f230ff58c8cbf18
Autor:
Katherine Priest, Anh Le, Amanuail Gebregzabheir, Hala Nijmeh, Gregory B. Reis, Melanie Mandell, Kurtis D. Davies, Carolyn Lawrence, Emily O’Donnell, Robert C. Doebele, Liming Bao, Dara L. Aisner, Erin L. Schenk
Publikováno v:
Kompass Neumología. :1-8
Los pacientes con CPNM metastásico portadores de una fusión del gen ROS1 suelen experimentar un control prolongado de la enfermedad con inhibidores de la tirosina quinasa (TKI) dirigidos a ROS1, aunque hay una heterogeneidad clínica significativa,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b800aee515c9574d25a738f275e9ca6f
https://doi.org/10.1159/000530596
https://doi.org/10.1159/000530596
Autor:
David S. Ettinger, Douglas E. Wood, Dara L. Aisner, Wallace Akerley, Jessica R. Bauman, Ankit Bharat, Debora S. Bruno, Joe Y. Chang, Lucian R. Chirieac, Malcolm DeCamp, Thomas J. Dilling, Jonathan Dowell, Gregory A. Durm, Scott Gettinger, Travis E. Grotz, Matthew A. Gubens, Aparna Hegde, Rudy P. Lackner, Michael Lanuti, Jules Lin, Billy W. Loo, Christine M. Lovly, Fabien Maldonado, Erminia Massarelli, Daniel Morgensztern, Thomas Ng, Gregory A. Otterson, Sandip P. Patel, Tejas Patil, Patricio M. Polanco, Gregory J. Riely, Jonathan Riess, Steven E. Schild, Theresa A. Shapiro, Aditi P. Singh, James Stevenson, Alda Tam, Tawee Tanvetyanon, Jane Yanagawa, Stephen C. Yang, Edwin Yau, Kristina M. Gregory, Miranda Hughes
Publikováno v:
Journal of the National Comprehensive Cancer Network. 21:340-350
The NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC) provide recommendations for management of disease in patients with NSCLC. These NCCN Guidelines Insights focus on neoadjuvant and adjuvant (also known as perioperative) systemic therapy opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a83660f7ba47623d490e51b0c7653ed9
https://doi.org/10.6004/jnccn.2023.0020
https://doi.org/10.6004/jnccn.2023.0020
Autor:
Thomas D. Lee, Dara L. Aisner, Marjorie Parker David, Celeste C. Eno, Jeffrey Gagan, Christopher D. Gocke, Natalya V. Guseva, Lisa Haley, Audrey N. Jajosky, Daniel Jones, Mahesh M. Mansukhani, Pawel Mroz, Sarah S. Murray, Kimberly J. Newsom, Vera Ashley Paulson, Somak Roy, Chase Rushton, Jeremy P. Segal, T. Niroshini Senaratne, Alexa J. Siddon, Petr Starostik, Jessica A. G. Van Ziffle, David Wu, Rena R. Xian, Sophia Yohe, Annette S. Kim
Publikováno v:
Blood Advances.
While molecular testing of hematologic malignancies is now standard of care, there is variability in practice and testing capabilities between different academic laboratories, with common questions arising on how to best meet clinical expectations. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466997e7f0665dda7f860d141b300963
https://doi.org/10.1182/bloodadvances.2023010149
https://doi.org/10.1182/bloodadvances.2023010149
Autor:
Antonio Jimeno, Aik-Choon Tan, Marileila Varella-Garcia, Barbara A. Frederick, Francois Wilhelm, Dara L. Aisner, Sarah M. Takimoto, Daniel Sehrt, Brian W. Vogler, Gregory N. Gan, Justin Eagles-Soukup, Adrian Umpierrez, Phuong Le, J. Jason Morton, David P. Astling, Magdalena J. Glogowska, Daniel W. Bowles, Stephen B. Keysar, Ryan T. Anderson
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e7717de4950956e210d0d4a5249dc
https://doi.org/10.1158/1535-7163.22497478
https://doi.org/10.1158/1535-7163.22497478
Autor:
Jennifer A. Low, Nisha Nanda, Michele Fernandes, Brian B. Tuch, Deborah Morosini, Philip J. Stephens, Yali Li, Dara L. Aisner, Marileila Varella-Garcia, Antonio Jimeno, Stephen Keysar, Adriana Estrada-Bernal, Anh T. Le, Aria Vaishnavi, Lara E. Davis, Robert C. Doebele
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a66340cae723397120cc48c8d7507e
https://doi.org/10.1158/2159-8290.22529550.v1
https://doi.org/10.1158/2159-8290.22529550.v1