Massive normalization of olfactory bulb output in mice with a 'monoclonal nose'

Autor: Benjamin Roland, Rebecca Jordan, Dara L Sosulski, Assunta Diodato, Izumi Fukunaga, Ian Wickersham, Kevin M Franks, Andreas T Schaefer, Alexander Fleischmann

Publikováno v: eLife, Vol 5 (2016)

Perturbations in neural circuits can provide mechanistic understanding of the neural correlates of behavior. In M71 transgenic mice with a “monoclonal nose”, glomerular input patterns in the olfactory bulb are massively perturbed and olfactory be

Externí odkaz: https://doaj.org/article/17be6909b1e04e3c94d6140f307a8624

Author response: Massive normalization of olfactory bulb output in mice with a 'monoclonal nose'

Autor: Dara L. Sosulski, Rebecca Jordan, Kevin M. Franks, Alexander Fleischmann, Izumi Fukunaga, Benjamin Roland, Assunta Diodato, Andreas T. Schaefer, Ian R. Wickersham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5aafea4510285fd41f3f59ea09fa909a
https://doi.org/10.7554/elife.16335.018

Mice with a 'Monoclonal Nose': Perturbations in an Olfactory Map Impair Odor Discrimination

Autor: Alexander Fleischmann, Mark W. Albers, Jennifer Kirkland, Monica Mendelsohn, Benjamin Shykind, Kevin M. Franks, Dan Feng Mei, Dara L. Sosulski, Meredith E. Glinka, Richard Axel, Yonghua Sun

Publikováno v: Neuron. 60:1068-1081

The recognition of odors is accomplished in the sensory epithelium where individual olfactory neurons express only one of 1,300 odorant receptor genes. Neurons expressing a given receptor project to two spatially invariant glomeruli in the olfactory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89285232b0dd3e5ef84690b9996858eb
https://doi.org/10.1016/j.neuron.2008.10.046

A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration

Autor: Zachary F. Mainen, Michael C. Quirk, Naoshige Uchida, Claudia E. Feierstein, Dara L. Sosulski

Publikováno v: Frontiers in Systems Neuroscience, Vol 3 (2009)
Frontiers in Systems Neuroscience
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Orbitofrontal cortex (OFC) is a region of prefrontal cortex implicated in the motivational control of behavior and in related abnormalities seen in psychosis and depression. It has been hypothesized that a critical mechanism in these disorders is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fdfc25d953c1707ae3172e6de81ffb
https://hdl.handle.net/10400.7/145

Recurrent Circuitry Dynamically Shapes the Activation of Piriform Cortex

Autor: Kevin M. Franks, Richard Axel, Abigail A. Mulligan, Steven A. Siegelbaum, Dara L. Sosulski, Marco J. Russo

Publikováno v: Neuron. (1):49-56

SummaryIn the piriform cortex, individual odorants activate a unique ensemble of neurons that are distributed without discernable spatial order. Piriform neurons receive convergent excitatory inputs from random collections of olfactory bulb glomeruli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad87fc726a7dcbd97ce9723e1941e63