Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dara Bracken-Clarke"'
Autor:
Elisabetta Xue, Dara Bracken-Clarke, Giovanni Maria Iannantuono, Hyoyoung Choo-Wosoba, James L Gulley, Charalampos S Floudas
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e54758 (2024)
BackgroundArtificial intelligence is increasingly being applied to many workflows. Large language models (LLMs) are publicly accessible platforms trained to understand, interact with, and produce human-readable text; their ability to deliver relevant
Externí odkaz:
https://doaj.org/article/054ce0b02e38414481ffc34088368d42
Autor:
James L Gulley, Ari VanderWalde, Emil Lou, Nishant Gandhi, Heloisa Soares, Charalampos S Floudas, Dara Bracken-Clarke, Harris Krause, Alex Farrell, Minh Phan, Rusha Patel, Nyall London
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/93817049c3694a7eb9203957ba9574a3
Autor:
James L Gulley, Ari VanderWalde, Emil Lou, Nishant Gandhi, Heloisa Soares, Charalampos S Floudas, Dara Bracken-Clarke, Harris Krause, Minh Phan, Rusha Patel, Phillip Walker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0db02fc69fc34140afba0cc9ede084c4
Autor:
Maria Davern, Cillian O’ Donovan, Noel E. Donlon, Eimear Mylod, Caoimhe Gaughan, Anshul Bhardwaj, Andrew D. Sheppard, Dara Bracken-Clarke, Christine Butler, Narayanasamy Ravi, Claire L. Donohoe, John V. Reynolds, Joanne Lysaght, Melissa J. Conroy
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 819 (2024)
The presence of an immunosuppressive tumour microenvironment in oesophageal adenocarcinoma (OAC) is a major contributor to poor responses. Novel treatment strategies are required to supplement current regimens and improve patient survival. This study
Externí odkaz:
https://doaj.org/article/3ca4eb6b6a0845a7a2adb872372af596
Autor:
Giovanni Maria Iannantuono, Dara Bracken-Clarke, Charalampos S. Floudas, Mario Roselli, James L. Gulley, Fatima Karzai
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The development of large language models (LLMs) is a recent success in the field of generative artificial intelligence (AI). They are computer models able to perform a wide range of natural language processing tasks, including content generation, que
Externí odkaz:
https://doaj.org/article/6a3c519940f54eab87d348289a43f5e8
Autor:
Maria Davern, Noel E. Donlon, Fiona O’ Connell, Andrew D. Sheppard, Conall Hayes, Ross King, Hugo Temperley, Christine Butler, Anshul Bhardwaj, Jenny Moore, Dara Bracken-Clarke, Claire Donohoe, Narayanasamy Ravi, John V. Reynolds, Stephen G. Maher, Melissa J. Conroy, Joanne Lysaght
Publikováno v:
Translational Oncology, Vol 20, Iss , Pp 101406- (2022)
Response rates to immune checkpoint blockade (ICB) remain low in oesophageal adenocarcinoma (OAC). Combining ICB with immunostimulatory chemotherapies to boost response rates is an attractive approach for converting ‘cold’ tumours into ‘hot’
Externí odkaz:
https://doaj.org/article/c52c824c793a4acdab0d58f23a41159d
Autor:
Maria Davern, Dara Bracken-Clarke, Noel E Donlon, Andrew D Sheppard, Fiona O connell, Aisling B Heeran, Klaudia Majcher, Melissa J Conroy, Eimear Mylod, Christine Butler, Claire Donohoe, Dearbhaile O' Donnell, Maevle Lowry, Anshul Bhardwaj, Narayanasamy Ravi, Ashanty A Melo, Jacintha O' Sullivan, John V Reynolds, Joanne Lysaght
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Aim Visceral obesity is a key risk factor in the development of oesophagogastric junctional adenocarcinoma (OGJ), predominantly via generation of systemic low grade inflammation. Obesity-induced inflammation promotes resistance to current standards o
Autor:
Maria davern, Noel E Donlon, Andrew D Sheppard, Fiona O' Connell, Klaudia D Majcher, Malika Grant, Aisling B. Heeran, Conall Hayes, Robert Farrell, Melissa J Conroy, Dermot O' Toole, Dara Bracken-Clarke, Emma Foley, Narayanasamy Ravi, Anshul Bhardwaj, John V. Reynolds, Stephen G. Maher, Jacintha O' Sullivan, Joanne Lysaght
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Background: Combining immunostimulatory chemotherapies with immunotherapy is an attractive strategy to enhance treatment responses in oesophagogastric junctional adenocarcinoma (OGJ). Methods: This study investigates the immunostimulatory properties
Autor:
Janice M. Walshe, Seamus O'Reilly, William Mullally, Patrick G. Morris, John James Kennedy, Rajnish Gupta, M. Keane, Cathy M. Kelly, Miriam O'Connor, Bryan T. Hennessy, K Duffy, Deirdre O'Mahony, Dara Bracken-Clarke, Andrew Padmore
Publikováno v:
Cancer Research. 80:P3-08
Background: The 21 gene recurrence score (OncotypeDx ®) is reimbursed in Ireland to guide adjuvant treatment decisions for ER+, LN-negative, human epidermal growth factor receptor 2 (HER2)-negative BC. There is emerging evidence supporting the clini
Publikováno v:
Cancers, Vol 13, Iss 3923, p 3923 (2021)
Cancers
Cancers
Simple Summary During the development and progression of lung tumors, processes such as necrosis and vascular invasion shed tumor cells or cellular components into various fluid compartments. Liquid biopsies consist of obtaining a bodily fluid, typic