Case report: Indolent drug-related pneumonitis with alectinib therapy in the treatment of non-small cell lung cancer

Autor: Xianmeng Chen, Daqing Xia, Xuqin Jiang, Lejie Cao, Jay H. Ryu, Xiaowen Hu

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Molecular targeting therapy is becoming the standard of care for some patients with anaplastic lymphoma kinase (ALK)-rearranged lung adenocarcinoma. Drug-related pneumonitis (DRP) has been identified as an infrequent but potentially severe adverse ef

Externí odkaz: https://doaj.org/article/25d76c7afe5b4ea5bc36cd698503f9c5

Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19

Autor: Sen Qun, Yulan Wang, Jun Chen, Xiang Huang, Hui Guo, Zhaohui Lu, Jinquan Wang, Changcheng Zheng, Yan Ma, Yuyou Zhu, Daqing Xia, Yinzhong Wang, Hongliang He, Yong Wang, Mingming Fei, Yihong Yin, Mao Zheng, Yehong Xu, Wei Ge, Fuyong Hu, Jian Zhou

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading worldwide. Measuring the prevention and control of the disease has become a matter requiring urgent focus.ObjectiveBased on coronavirus disease 2019 (COVID-

Externí odkaz: https://doaj.org/article/4804f8a9d7dd4cc09a02742aa1b9f174

Photothermally triggered melting and perfusion: responsive colloidosomes for cytosolic delivery of membrane-impermeable drugs in tumor therapy

Autor: Tao Ding, Jing Zhu, Haidi Guan, Daqing Xia, Yuxin Xing, Jixi Huang, Zhenqiang Wang, Kaiyong Cai, Jixi Zhang

Publikováno v: Journal of Materials Chemistry B. 10:1103-1115

A cell membrane barrier which dominates the therapeutic efficacy and systemic side effects is a major bottleneck in the field of drug delivery. Herein, a therapeutic system capable of photothermally triggered on-demand and cytosolic delivery was achi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293890c47b8de442cfdf12ca7ae76d12
https://doi.org/10.1039/d1tb02503a

Risk-adapted Treatment Strategy For COVID-19 Patients

Autor: Mingming Fei, Jinquan Wang, Hongliang He, Daqing Xia, Yihong Yin, Hui Guo, Jian Zhou, Yan Ma, Mao Zheng, treat novel coronavirus pneumonia in Wuhan, Yehong Xu, Zhaohui Lu, Yong Wang, Yuyou Zhu, Changcheng Zheng, Yinzhong Wang

Publikováno v: International Journal of Infectious Diseases, Vol 94, Iss, Pp 74-77 (2020)
International Journal of Infectious Diseases
International journal of infectious diseases, 94:74-77

Highlights • There are no clear expert consensus or guidelines on how to treat COVID-19. • We developed a risk-adapted treatment approach according to the illness severity. • This strategy was effective in symptoms alleviation and chest CT reco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e9a7e5fdbb92e6718779c09e7b11c9
http://www.sciencedirect.com/science/article/pii/S120197122030179X

Tocilizumab in patients with moderate or severe COVID-19: a randomized, controlled, open-label, multicenter trial

Autor: Xiaoling Xu, Zhen Peng, Yonggang Zhou, Jun Chen, Daqing Xia, Yun Yang, Jumei Wang, Aijun Pan, Min Zhang, Xiaodong Mei, Xin Yao, Wei Li, Haiming Wei, Mingfeng Han, Lin Dong, Binqing Fu, Wei Shi, Min Li, Xiao jing Wang, Dongsheng Wang, Tianjun Yang, Yan Ma, Xiaowen Hu, Fei Xu, Xiaoyu Zhu, Dongliang Yang, Yubei Sun, Liangye Sun

Publikováno v: Frontiers of Medicine

Tocilizumab has been reported to attenuate the “cytokine storm” in COVID-19 patients. We attempted to verify the effectiveness and safety of tocilizumab therapy in COVID-19 and identify patients most likely to benefit from this treatment. We cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d37396e0e649a86039f9cd6ee5ba6a
https://pubmed.ncbi.nlm.nih.gov/33687643