Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Daping Fan"'
Autor:
Ethan A. Older, Jian Zhang, Zachary E. Ferris, Dan Xue, Zheng Zhong, Mary K. Mitchell, Michael Madden, Yuzhen Wang, Hexin Chen, Prakash Nagarkatti, Mitzi Nagarkatti, Daping Fan, Melissa Ellermann, Yong-Xin Li, Jie Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The trillions of microorganisms inhabiting the human gut are intricately linked to human health. While specific microbes have been associated with diseases, microbial abundance alone cannot reveal the molecular mechanisms involved. One such
Externí odkaz:
https://doaj.org/article/610f9c86477c44328236ec90fbbd6581
Autor:
Jiawei Wei, Huan Ning, Octavio Ramos‐Espinosa, Christopher S. Eickhoff, Rong Hou, Qinghong Wang, Mingui Fu, Ethan Y. Liu, Daping Fan, Daniel F. Hoft, Jianguo Liu
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 8, Pp 249-262 (2024)
Abstract Immune evasion of Mycobacterium tuberculosis (Mtb) facilitates intracellular bacterial growth. The mechanisms of immune evasion, however, are still not fully understood. In this study, we reveal that tristetraprolin (TTP), one of the best ch
Externí odkaz:
https://doaj.org/article/bfbff8153cac4729b6c123735822382c
Autor:
Thomas D. Cardaci, Brandon N. VanderVeen, Brooke M. Bullard, Sierra J. McDonald, Christian A. Unger, Reilly T. Enos, Daping Fan, Kandy T. Velázquez, Norma Frizzell, Espen E. Spangenburg, E. Angela Murphy
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 124-137 (2024)
Abstract Background More than 650 million people are obese (BMI > 30) worldwide, which increases their risk for several metabolic diseases and cancer. While cachexia and obesity are at opposite ends of the weight spectrum, leading many to suggest a p
Externí odkaz:
https://doaj.org/article/8e58be7d41294061abe0faa6c1ffb64b
Autor:
Sierra J. McDonald, Brooke M. Bullard, Brandon N. VanderVeen, Thomas D. Cardaci, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy
Publikováno v:
Physiological Reports, Vol 11, Iss 19, Pp n/a-n/a (2023)
Abstract It has been suspected that tumor resection surgery itself may accelerate breast cancer (BC) lung metastasis in some patients. Emodin, a natural anthraquinone found in the roots and rhizomes of various plants, exhibits anticancer activity. We
Externí odkaz:
https://doaj.org/article/13cc97b51bdd4dc68a473e6394bf91f0
Autor:
Brandon N. VanderVeen, Thomas D. Cardaci, Sierra J. McDonald, Sarah S. Madero, Christian A. Unger, Brooke M. Bullard, Reilly T. Enos, Kandy T. Velázquez, Jason L. Kubinak, Daping Fan, E. Angela Murphy
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 1-15 (2022)
Fluorouracil/5-flourouracil (5FU) is a first-line chemotherapy drug for many cancer types; however, its associated toxicities contribute to poor quality of life and reduced dose intensities negatively impacting patient prognosis. While obesity remain
Externí odkaz:
https://doaj.org/article/5a08eb54ec3d41e1976ad2f858905259
Autor:
Patrice Cunningham, Emma Patton, Brandon N. VanderVeen, Christian Unger, Ahmed Aladhami, Reilly T. Enos, Sarah Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy, Kandy T. Velázquez
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Quercetin is an organic flavonoid present in several fruits and vegetables. The anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and neuroprotective properties demonstrated by this dietary supplement
Externí odkaz:
https://doaj.org/article/00975738a9c948089982fd3ae5c20391
Publikováno v:
Cells, Vol 13, Iss 5, p 421 (2024)
Increased production of extracellular matrix is a necessary response to tissue damage and stress. In a normal healing process, the increase in extracellular matrix is transient. In some instances; however, the increase in extracellular matrix can per
Externí odkaz:
https://doaj.org/article/839d7ba5a703408eab2a8823099d164b
Autor:
Sijia Tang, Lei Shi, Breona T. Luker, Channen Mickler, Bhavana Suresh, Gregory B. Lesinski, Daping Fan, Yuan Liu, Ming Luo
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background The immunosuppressive microenvironment in pancreatic ductal adenocarcinoma is a major factor that limits the benefits of immunotherapy, especially immune checkpoint blockade. One viable strategy for reverting the immunosuppressive
Externí odkaz:
https://doaj.org/article/ff1addfd18b640348a061837b7595709
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Resistance to gefitinib remains a major obstacle for the successful treatment of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. In this paper, we studied the precise actions of circular
Externí odkaz:
https://doaj.org/article/21b81f0c6de64bf9923698e7df9a3f1a
Autor:
Allison K. Meyers, Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Likun Duan, Juan Liu, Qianyi Zhang, Rajesh K. Manne, Felipe Lorenzo, Matthew A. Quinn, Qianqian Song, Daping Fan, Hui-Kuan Lin, Cristina M. Furdui, Jason W. Locasale, Charles E. McCall, Xuewei Zhu
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111941- (2023)
Summary: Activating the macrophage NLRP3 inflammasome can promote excessive inflammation with severe cell and tissue damage and organ dysfunction. Here, we show that pharmacological or genetic inhibition of pyruvate dehydrogenase kinase (PDHK) signif
Externí odkaz:
https://doaj.org/article/9e44575ee34a4202a7a3e462e4561170