Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daphnee S. Pushparajah"'
Autor:
Daphnee S. Pushparajah
Publikováno v:
The Patient
Patients are increasingly recognised as the true customers of healthcare. By providing insights and perspectives, patients can help the wider healthcare community better understand their needs and ultimately enhance the value of healthcare solutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f02055f2e28474c3b0bafe4a9d8211
http://europepmc.org/articles/PMC5766722
http://europepmc.org/articles/PMC5766722
Autor:
Tammy S Ice, Nadia Thyssen, Elizabeth Manning, Mitch Herndon, Stephen Yates, Daphnee S Pushparajah, Wendy Frye
Publikováno v:
Therapeutic Innovation & Regulatory Science
Background Biopharmaceutical companies are piloting patient experience surveys (PES) to help enhance patient satisfaction with clinical studies. However, most PES have been conducted at study close-out, which can hinder recall and responsiveness, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5744cabb87e794ebf20dc5e7bc912f50
https://pubmed.ncbi.nlm.nih.gov/31965539
https://pubmed.ncbi.nlm.nih.gov/31965539
Publikováno v:
Environmental Toxicology. 32:764-775
The current studies investigate whether synergistic or antagonistic interactions in the upregulation of CYP1 activity occur in binary mixtures of polycyclic aromatic hydrocarbons (PAHs) involving benzo[a]pyrene and five other structurally diverse PAH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3d012b1b9463aebe935a703d966d4c8
https://doi.org/10.1002/tox.22276
https://doi.org/10.1002/tox.22276
Autor:
Matthias Schneider, Daphnee S. Pushparajah, Kirsten Lerstrøm, Caroline Gordon, Enkeleida Nikaï, David A. Isenberg, Yvonne Norton
Publikováno v:
Rheumatology (Oxford, England)
Objective. The objective of this study was to explore the burden of SLE and its effect on patients’ lives. Methods. The Lupus European Online (LEO) survey included patient-designed questions on demographics, SLE diagnosis, and the impact of SLE on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c9144988bc8bb7e45332edb59d8455
https://doi.org/10.1093/rheumatology/ket300
https://doi.org/10.1093/rheumatology/ket300
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 40
The objectives of the present study were two-fold: (a) to evaluate the role of molecular shape on the interaction of polycyclic aromatic hydrocarbons (PAHs) with the Ah receptor and CYP1A1 upregulation, and (b) to evaluate the potential of PAHs to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92ba6270fb6a21eeaaca1c3753ba688
https://pubmed.ncbi.nlm.nih.gov/28104439
https://pubmed.ncbi.nlm.nih.gov/28104439
Autor:
Yvonne C.M. Staal, Daphnee S. Pushparajah, Frederik J. van Schooten, Marcel H. M. van Herwijnen, Ralph W.H. Gottschalk, L.M. Maas, Costas Ioannides, Joost H.M. van Delft
Publikováno v:
Mutagenesis, 23(6), 491-499. Oxford University Press
Although exposure to polycyclic aromatic hydrocarbons (PAHs) occurs mostly through mixtures, hazard and risk assessment are mostly based on the effects caused by individual compounds. The objective of the current study was to investigate whether inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c4e371bf234b2421908c6a56b80d2b
https://doi.org/10.1093/mutage/gen041
https://doi.org/10.1093/mutage/gen041
Autor:
Costas Ioannides, Nick Plant, David F.V. Lewis, Meera Umachandran, Tariq Nazir, Daphnee S. Pushparajah, Kathryn E. Plant
Publikováno v:
Toxicology in Vitro. 22:128-145
Exposure of precision-cut rat liver slices to six structurally diverse polycyclic aromatic hydrocarbons, namely benzo[a]pyrene, benzo[b]fluoranthene, dibenzo[a,h]anthracene, dibenzo[a,l]pyrene, fluoranthene and 1-methylphenanthrene, led to induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0760fb3a256240ea4b21e3ac48de9c18
https://doi.org/10.1016/j.tiv.2007.08.014
https://doi.org/10.1016/j.tiv.2007.08.014
Publikováno v:
Toxicology. 231:68-80
The principal objective was to ascertain whether precision-cut tissue slices can be used to evaluate the potential of chemicals to induce CYP1, epoxide hydrolase and glutathione S-transferase activities, all being important enzymes involved in the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46eae0f324f9c7713fde1623aff2deb1
https://doi.org/10.1016/j.tox.2006.11.063
https://doi.org/10.1016/j.tox.2006.11.063
Publikováno v:
Environmental toxicology. 32(3)
The current studies investigate whether synergistic or antagonistic interactions in the upregulation of CYP1 activity occur in binary mixtures of polycyclic aromatic hydrocarbons (PAHs) involving benzo[a]pyrene and five other structurally diverse PAH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c6145c39317e0f74851025cd5e9432d
https://pubmed.ncbi.nlm.nih.gov/27099206
https://pubmed.ncbi.nlm.nih.gov/27099206
Publikováno v:
Journal of Medicines Development Sciences. 1:74
The value of collaborations and partnerships between different stakeholders to achieve optimum outcomes in the medicines research and development process is being recognised. Historically, there has been a lack of collaboration with patients and many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487b216c687a8c9d60392fc0df49977b
https://doi.org/10.18063/jmds.v1i1.122
https://doi.org/10.18063/jmds.v1i1.122