Výsledky vyhledávání - "Daphne Wei-Chen Chen"

Akademický článek

Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia.

Autor: Malak Yahia Qattan, Emyr Yosef Bakker, Ramkumar Rajendran, Daphne Wei-Chen Chen, Vaskar Saha, Jizhong Liu, Leo Zeef, Jean-Marc Schwartz, Luciano Mutti, Constantinos Demonacos, Marija Krstic-Demonacos

Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0178606 (2017)

Glucocorticoids (GCs) and topoisomerase II inhibitors are used to treat acute lymphoblastic leukaemia (ALL) as they induce death in lymphoid cells through the glucocorticoid receptor (GR) and p53 respectively. Mechanisms underlying ALL cell death and

Externí odkaz: https://doaj.org/article/d6ba7f280e314fbc85e0a0243026649b

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Quantitative analysis and modeling of glucocorticoid-controlled gene expression

Autor: Marija Krstic-Demonacos, Daphne Wei Chen Chen, Constantinos Demonacos, Jean-Marc Schwartz, James T. Lynch

Publikováno v: Pharmacogenomics. 11(11)

Aims: Glucocorticoid hormones are used extensively in the clinic for the treatment of acute lymphoblastic leukemia. Despite intensive research, the molecular mechanisms of glucocorticoid receptor (GR)-mediated transcriptional events that lead to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4766a8d95d605effd0718a86d0f386
https://pubmed.ncbi.nlm.nih.gov/21121775

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