Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daphne Su Lyn Gardner"'
Autor:
Robyn Su May Lim, Daphne Su Lyn Gardner, Yong Mong Bee, Yin Bun Cheung, Joann Bairavi, Mihir Gandhi, Su-Yen Goh, Emily Tse Lin Ho, Xinyi Lin, Ngiap Chuan Tan, Tunn Lin Tay, Eric Andrew Finkelstein
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background The outcomes for those with type 2 diabetes mellitus (T2DM) in Singapore are poor. In this TRIal to slow the Progression Of Diabetes (TRIPOD), we will evaluate the effectiveness and cost-effectiveness of a comprehensive diabetes m
Externí odkaz:
https://doaj.org/article/3a57e3f1d95b4295800b980f5887bbe0
Autor:
Sarah Ying Tse Tan, Suresh Rama Chandran, Jielin Yew, Andy Jun‐Wei Wong, Daphne Su‐Lyn Gardner
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 6, Pp 786-789 (2024)
Abstract Fulminant type 1 diabetes (FT1D) is a unique subtype of type 1 diabetes, characterized by acute absolute insulin deficiency, severe ketosis, and increased risk of hypoglycemia, glycemic variability and microvascular complications. Seven peop
Externí odkaz:
https://doaj.org/article/3022c268373d4a8491e8df3c2b793f49
Autor:
Joann Bairavi, Daphne Su-Lyn Gardner, Ester Yeoh, Kwang Wei Tham, Mihir Gandhi, Ngiap Chuan Tan, Phong Ching Lee, Robyn Su May Lim, Thofique Adamjee, Yin Bun Cheung, Yong Mong Bee, Eric Andrew Finkelstein
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background Type 2 diabetes (T2D), a major risk factor for cardiovascular disease and other adverse health conditions, is on the rise in Singapore. TRIPOD is a randomized controlled trial aimed to determine whether complementing usual care wi
Externí odkaz:
https://doaj.org/article/881eeabd0b334a48b61510cc500a5d79
Autor:
Hwee Hui Lau, Nicole A. J. Krentz, Fernando Abaitua, Marta Perez-Alcantara, Jun-Wei Chan, Jila Ajeian, Soumita Ghosh, Yunkyeong Lee, Jing Yang, Swaraj Thaman, Benoite Champon, Han Sun, Alokkumar Jha, Shawn Hoon, Nguan Soon Tan, Daphne Su-Lyn Gardner, Shih Ling Kao, E. Shyong Tai, Anna L. Gloyn, Adrian Kee Keong Teo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The coding variant (p.Arg192His) in the transcription factor PAX4 is associated with an altered risk for type 2 diabetes (T2D) in East Asian populations. In mice, Pax4 is essential for beta cell formation but its role on human beta cell deve
Externí odkaz:
https://doaj.org/article/04c9903c45a041a292092f38195e3bde
Autor:
Suresh Rama Chandran, Jaydutt Bhalshankar, Rashida Farhad Vasanwala, Yi Zhao, Katharine R. Owen, Daphne Su-Lyn Gardner
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 9 (2018)
Background: Young adults with diabetes in Asia represent a heterogeneous group. Using traditional clinical criteria to preselect individuals for testing for maturity-onset diabetes of the young (MODY) may exclude a large proportion from testing. High
Externí odkaz:
https://doaj.org/article/a68ac8f055d2437492a05e8c06862f8f
Autor:
Yaw Sing Tan, Kok Onn Lee, Daphne Su-Lyn Gardner, Wei Xuan Tan, Chandra S. Verma, Shawn Hoon, Nur Shabrina Amirruddin, Yong Mong Bee, Adrian Kee Keong Teo
Publikováno v:
Diabetologia. 64:2534-2549
We studied the effects of heterozygous human INS gene mutations on insulin secretion, endoplasmic reticulum (ER) stress and other mechanisms in both MIN6 and human induced pluripotent stem cells (hiPSC)-derived beta-like cells, as well as the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9be53470bf1ef03f5331aba22f9d232d
https://doi.org/10.1007/s00125-021-05530-3
https://doi.org/10.1007/s00125-021-05530-3
Autor:
Huee Boon Lim, Yoke Ling Chan, Suresh Chandran, Kristy Tian, Ai Heong Chong, Haur Yueh Lee, Daphne Su-Lyn Gardner
Publikováno v:
AACE Clinical Case Reports
AACE Clinical Case Reports, Vol 7, Iss 6, Pp 346-349 (2021)
AACE Clinical Case Reports, Vol 7, Iss 6, Pp 346-349 (2021)
Objective Insulin allergy, although uncommon, poses a significant challenge in those with type 1 diabetes mellitus (T1D) as insulin replacement is a necessity. Our objective is to describe a patient in whom rapid desensitization to insulin aspart was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc87c99eff297094953456aa46afb0ab
http://europepmc.org/articles/PMC8573278
http://europepmc.org/articles/PMC8573278
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2021)
Endocrinology, Diabetes & Metabolism Case Reports
Endocrinology, Diabetes & Metabolism Case Reports
Summary Thyroid storm is a rare but potentially life-threatening complication of excessive thyroid hormone action. It is associated with a hypercoagulable state and reported to increase the risk of thromboembolism. However, the role of anticoagulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a106f845f0ea20e797f2d576177415
https://edm.bioscientifica.com/view/journals/edm/2021/1/EDM20-0118.xml
https://edm.bioscientifica.com/view/journals/edm/2021/1/EDM20-0118.xml
Publikováno v:
Diabetes & Metabolism Journal
Background: There is little longitudinal information on psychological burden and metabolic outcomes in young adults with dia betes (YAD) in Asia. We aimed to evaluate the association between psychological status and glycemia at baseline and 2 years f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43f5dd7f613ce9e29ee9b9c303e0809
http://europepmc.org/articles/PMC7850875
http://europepmc.org/articles/PMC7850875
Autor:
Suresh Rama Chandran, Hong Chang Tan, Qifan Chen, Phong Ching Lee, Daphne Su-Lyn Gardner, Yun Ann Chin, Amanda Yun Rui Lam, Ming Ming Teh, Yong Mong Bee
Publikováno v:
Journal of Diabetes Science and Technology. :193229682311573
Background: Delayed initiation and inadequate titration remain critical challenges to optimizing insulin therapy in type 2 diabetes (T2D). We aimed to study whether hemoglobin A1c (HbA1c) can be lowered in people with insulin-treated T2D using telemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd61c8c3f8723cdb9a71f450e47e786
https://doi.org/10.1177/19322968231157387
https://doi.org/10.1177/19322968231157387