Zobrazeno 1 - 7
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pro vyhledávání: '"Daphne Staley"'
Publikováno v:
Endocrinology. 119:2537-2546
The stimulation of gonadotropin release from pituitary cell cultures by GnRH has been linked to inositol phospholipid breakdown to diacylglycerols and subsequent activation of protein kinase C as well as Ca2+ mobilization. In order to examine the mea
Autor:
Daphne Staley, Barry R. Ganong, P. Michael Conn, Robert M. Bell, James E. Neidel, James Ebeling
Publikováno v:
Biochemical and biophysical research communications. 126(1)
A series of diacylglycerols were synthesized with varying lengths and substituents in order to establish the structure-activity relationship between each with activation of protein kinase C and stimulation of a biological response system (pituitary l
Publikováno v:
Endocrinology. 115(5)
In the present work we examined the effect of cationic polymers on the pituitary gonadotrope. Such polymers are widely used to anchor gonadotropes and other cell types to culture dishes and other substrata to which they are not normally adherent. Hom
Publikováno v:
Journal of steroid biochemistry. 23(5B)
This work summarizes some of our studies related to the mechanism of action of gonadotropin releasing hormone including those leading to identification of the three steps of the gonadotropin releasing process: receptor binding, mobilization of extrac
Publikováno v:
Molecular and cellular endocrinology. 56(1-2)
Gonadotropin releasing hormone (GnRH)-stimulated release of the alpha subunit common to the gonadotropins and to thyrotropin was studied in rat pituitary cell cultures. In these studies we took advantage of a recently prepared antiserum specific for