Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daphne S, Bindels"'
Autor:
Gerard G Lambert, Hadrien Depernet, Guillaume Gotthard, Darrin T Schultz, Isabelle Navizet, Talley Lambert, Stephen R Adams, Albertina Torreblanca-Zanca, Meihua Chu, Daphne S Bindels, Vincent Levesque, Jennifer Nero Moffatt, Anya Salih, Antoine Royant, Nathan C Shaner
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000936 (2020)
Using mRNA sequencing and de novo transcriptome assembly, we identified, cloned, and characterized 9 previously undiscovered fluorescent protein (FP) homologs from Aequorea victoria and a related Aequorea species, with most sequences highly divergent
Externí odkaz:
https://doaj.org/article/1615fde95fbf4dc185013abf874918db
Autor:
Laura van Weeren, Christian Blum, Jente Stouthamer, Daphne S. Bindels, Vinod Subramaniam, Theodorus W. J. Gadella, Jord C. Prangsma, Robert Molenaar, Lindsay Haarbosch, Willem L. Vos
Publikováno v:
The journal of Physical Chemistry. B, 124(8), 1383-1391. American Chemical Society
The Journal of physical chemistry B, 124(8), 1383-1391. American Chemical Society
The Journal of Physical Chemistry. B
The Journal of physical chemistry B, 124(8), 1383-1391. American Chemical Society
The Journal of Physical Chemistry. B
The fluorescence quantum yield of four representative red fluorescent proteins mCherry, mKate2, mRuby2, and the recently introduced mScarlet was investigated. The excited state lifetimes were measured as a function of the distance to a gold mirror in
Autor:
Lindsay Haarbosch, Daphne S. Bindels, Marten Postma, Laura van Weeren, Theodorus W. J. Gadella
Publikováno v:
Nature Protocols, 15(2), 450-478. Nature Publishing Group
Genetically encoded fluorescent proteins (FPs) are highly utilized in cell biology research to study proteins of interest or signal processes using biosensors. To perform well in specific applications, these FPs require a multitude of tailored proper
Autor:
Wei-Chieh Chiang, R. Luke Wiseman, Joseph Carroll, Amanda Nguyen, Julia M. D. Grandjean, Heike Kroeger, Jennifer Okalova, Jonathan H. Lin, Neil Grimsey, Evan T. Powers, Michel Michaelides, Jeffery W. Kelly, Daphne S. Bindels, Rebecca Mastey
Dysregulation of the endoplasmic reticulum (ER) Unfolded Protein Response (UPR) is implicated in the pathology of many human diseases associated with ER stress. Inactivating genetic variants in the UPR regulator Activating Transcription Factor 6 (ATF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::913b5b7d900ab5ff510d3883f7ce149e
https://doi.org/10.1101/2020.10.04.325019
https://doi.org/10.1101/2020.10.04.325019
Autor:
Daphne S. Bindels, Amanda Nguyen, Jonathan H. Lin, Julia M. D. Grandjean, Wei-Chieh Chiang, Rebecca Mastey, Michel Michaelides, Evan T. Powers, Jeffery W. Kelly, Joseph Carroll, Heike Kroeger, R. Luke Wiseman, Jennifer Okalova, Neil Grimsey
Publikováno v:
SSRN Electronic Journal.
Dysregulation of the endoplasmic reticulum (ER) Unfolded Protein Response (UPR) is implicated in the pathology of many human diseases associated with ER stress. Inactivating genetic variants in the UPR regulator Activating Transcription Factor 6 (ATF
Autor:
P. Boronat, Louis Maes, I.J.P. de Esch, Marco Siderius, David G. Brown, Rob Leurs, A.R. Blaazer, Payman Sadek, Geert Jan Sterk, E. de Heuvel, Daphne S. Bindels, M. Oberholzer, Albert J. Kooistra, Nathan C. Shaner, T. van der Meer, Guy Caljon, A.K. Singh
Publikováno v:
Bioorganic and Medicinal Chemistry, 27(18), 4013-4029. Elsevier Limited
de Heuvel, E, Singh, A K, Boronat, P, Kooistra, A J, van der Meer, T, Sadek, P, Blaazer, A R, Shaner, N C, Bindels, D S, Caljon, G, Maes, L, Sterk, G J, Siderius, M, Oberholzer, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2) ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 4013-4029 . https://doi.org/10.1016/j.bmc.2019.06.026
Bioorganic and medicinal chemistry
de Heuvel, E, Singh, A K, Boronat, P, Kooistra, A J, van der Meer, T, Sadek, P, Blaazer, A R, Shaner, N C, Bindels, D S, Caljon, G, Maes, L, Sterk, G J, Siderius, M, Oberholzer, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2) ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 4013-4029 . https://doi.org/10.1016/j.bmc.2019.06.026
Bioorganic and medicinal chemistry
Inhibitors against Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) and B2 (TbrPDEB2) have gained interest as new treatments for human African trypanosomiasis. The recently reported alkynamide tetrahydrophthalazinones, which show submicromolar acti
Autor:
Nathan C. Shaner, Daphne S. Bindels, Marten Postma, Theodorus W. J. Gadella, Joachim Goedhart, Marieke Mastop
Publikováno v:
Scientific Reports, 7:11999. Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Scientific Reports
Genetically encoded Förster Resonance Energy Transfer (FRET) based biosensors report on changes in biochemical states in single living cells. The performance of biosensors depends on their brightness and dynamic range, which are dependent on the cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a32c02e9b6699d064ab152db9df2123
https://dare.uva.nl/personal/pure/en/publications/characterization-of-a-spectrally-diverse-set-of-fluorescent-proteins-as-fret-acceptors-for-mturquoise2(77b451dc-0852-4b41-b469-dd0f39742628).html
https://dare.uva.nl/personal/pure/en/publications/characterization-of-a-spectrally-diverse-set-of-fluorescent-proteins-as-fret-acceptors-for-mturquoise2(77b451dc-0852-4b41-b469-dd0f39742628).html
Autor:
Lindsay Haarbosch, Antoine Royant, Mark A. Hink, Daphne S. Bindels, Marten Postma, Theodorus W. J. Gadella
Publikováno v:
European Microscopy Congress 2016: Proceedings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da00a4327b305cd2faa9249fef59d477
https://doi.org/10.1002/9783527808465.emc2016.8648
https://doi.org/10.1002/9783527808465.emc2016.8648
Autor:
Daphne S, Bindels, Joachim, Goedhart, Mark A, Hink, Laura, van Weeren, Linda, Joosen, Theodorus W J, Gadella
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1076
Nowadays, fluorescent protein (FP) variants have been engineered to fluoresce in all different colors; to display photoswitchable, or photochromic, behavior; or to show yet other beneficial properties that enable or enhance a still growing set of new