Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daphne Dupéré-Richér"'
Autor:
Teresa Ezponda, Daphné Dupéré-Richer, Christine M. Will, Eliza C. Small, Nobish Varghese, Tej Patel, Behnam Nabet, Relja Popovic, Jon Oyer, Marinka Bulic, Yupeng Zheng, Xiaoxiao Huang, Mrinal Y. Shah, Sayantan Maji, Alberto Riva, Manuela Occhionorelli, Giovanni Tonon, Neil Kelleher, Jonathan Keats, Jonathan D. Licht
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 628-640 (2017)
Loss or inactivation of the histone H3K27 demethylase UTX occurs in several malignancies, including multiple myeloma (MM). Using an isogenic cell system, we found that loss of UTX leads to deactivation of gene expression ultimately promoting the prol
Externí odkaz:
https://doaj.org/article/c8e4f4dce46b4e28975494365da80fbf
Autor:
Luca A Petruccelli, Daphné Dupéré-Richer, Filippa Pettersson, Hélène Retrouvey, Sophia Skoulikas, Wilson H Miller
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20987 (2011)
Histone deacetylase inhibitors (HDACi) are promising anti-cancer agents, however, their mechanisms of action remain unclear. In acute myeloid leukemia (AML) cells, HDACi have been reported to arrest growth and induce apoptosis. In this study, we eluc
Externí odkaz:
https://doaj.org/article/c47aa15086ee447286cb29df7ad14528
Autor:
Michael F. Emmons, Richard L. Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, Edward Seto, John M. Koomen, Jiannong Li, Y. Ann Chen, Peter A. Forsyth, Jonathan D. Licht, Keiran S. M. Smalley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Melanomas can adopt multiple transcriptional states. Little is known about the epigenetic drivers of these cell states, limiting our ability to regulate melanoma heterogeneity. Here, we identify stress-induced HDAC8 activity as driving melan
Externí odkaz:
https://doaj.org/article/eaa6d6439c614e83a09975f61db4c4e0
Autor:
Jonathan D. Licht, Richard B. Lock, Matthew D. Hall, Adolfo A. Ferrando, Richard L. Bennett, Alberto Riva, Min Shen, Christine M. Will, Jon A. Oyer, Marta Kulis, Alok Swaroop, Catalina Troche, Heidi L. Casellas Román, Duohui Jing, Jacob S. Roth, Daphne Dupéré-Richér, Crissandra Piper, Jonathan H. Shrimp, Julia Hlavka-Zhang, Jianping Li
ALL patients with NSD2 mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517a96a467d2058c318cf5df5b010bc5
https://doi.org/10.1158/2159-8290.22540613
https://doi.org/10.1158/2159-8290.22540613
Autor:
Jonathan D. Licht, Richard B. Lock, Matthew D. Hall, Adolfo A. Ferrando, Richard L. Bennett, Alberto Riva, Min Shen, Christine M. Will, Jon A. Oyer, Marta Kulis, Alok Swaroop, Catalina Troche, Heidi L. Casellas Román, Duohui Jing, Jacob S. Roth, Daphne Dupéré-Richér, Crissandra Piper, Jonathan H. Shrimp, Julia Hlavka-Zhang, Jianping Li
Supplementary Methods and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f527e42d7609e21d0ce6a0dc9cd8297f
https://doi.org/10.1158/2159-8290.22540619.v1
https://doi.org/10.1158/2159-8290.22540619.v1
Autor:
Jonathan D. Licht, Richard B. Lock, Matthew D. Hall, Adolfo A. Ferrando, Richard L. Bennett, Alberto Riva, Min Shen, Christine M. Will, Jon A. Oyer, Marta Kulis, Alok Swaroop, Catalina Troche, Heidi L. Casellas Román, Duohui Jing, Jacob S. Roth, Daphne Dupéré-Richér, Crissandra Piper, Jonathan H. Shrimp, Julia Hlavka-Zhang, Jianping Li
Mutations in epigenetic regulators are common in relapsed pediatric acute lymphoblastic leukemia (ALL). Here, we uncovered the mechanism underlying the relapse of ALL driven by an activating mutation of the NSD2 histone methyltransferase (p.E1099K).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d81e3bd352ab69e448030a91c43dd4
https://doi.org/10.1158/2159-8290.c.6549425.v1
https://doi.org/10.1158/2159-8290.c.6549425.v1
Autor:
Michael F. Emmons, Richard L. Bennett, Alberto Riva, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, Edward Seto, John M. Koomen, Jiannong Li, Y. Ann Chen, Peter A. Forsyth, Jonathan D. Licht, Keiran S.M. Smalley
Melanomas are heterogeneous and adopt multiple transcriptional states that can confer an invasive phenotype and resistance to therapy. Little is known about the epigenetic drivers of these cell states, limiting our ability to regulate melanoma hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771b58158958d450b536956d370ce84a
https://doi.org/10.1101/2022.10.12.511971
https://doi.org/10.1101/2022.10.12.511971
Autor:
Michael Emmons, Richard Bennett, Alberto Riva, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, John Koomen, Jiannong Li, Ann Chen, Edward Seto, Jonathan Licht, Keiran Smalley
Publikováno v:
Cancer Research. 83:3606-3606
Melanomas are heterogeneous and adopt multiple transcriptional states that can confer an invasive phenotype and resistance to therapy. Little is known about the epigenetic drivers of these cell states, limiting our ability to regulate melanoma hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47705bb968a6d0ff6e81a6ebe7977131
https://doi.org/10.1158/1538-7445.am2023-3606
https://doi.org/10.1158/1538-7445.am2023-3606
Autor:
Jianping, Li, Julia, Hlavka-Zhang, Jonathan H, Shrimp, Crissandra, Piper, Daphne, Dupéré-Richér, Jacob S, Roth, Duohui, Jing, Heidi L, Casellas Román, Catalina, Troche, Alok, Swaroop, Marta, Kulis, Jon A, Oyer, Christine M, Will, Min, Shen, Alberto, Riva, Richard L, Bennett, Adolfo A, Ferrando, Matthew D, Hall, Richard B, Lock, Jonathan D, Licht
Publikováno v:
Cancer discovery. 12(1)
Mutations in epigenetic regulators are common in relapsed pediatric acute lymphoblastic leukemia (ALL). Here, we uncovered the mechanism underlying the relapse of ALL driven by an activating mutation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1102c27f0d79bfe42477d3c1ce517985
https://pubmed.ncbi.nlm.nih.gov/34417224
https://pubmed.ncbi.nlm.nih.gov/34417224