Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Daphne D. Blumberg"'
Autor:
Jessica S. Kelsey, Daphne D. Blumberg
Publikováno v:
Biology Open, Vol 2, Iss 4, Pp 396-406 (2013)
Summary The AmpA protein reduces cell adhesion, thereby influencing cell migration in Dictyostelium. To understand how ampA influences cell migration, second site suppressors of an AmpA overexpressing cell line were created by REMI mutagenesis. Mutan
Externí odkaz:
https://doaj.org/article/4db9bce367a04b9fbf9819d97545be78
Publikováno v:
Differentiation. 86:1-12
The Dictyostelium discoideum ampA gene encodes a multifunctional regulator protein that modulates cell–cell and cell–substrate adhesions and actin polymerization during growth and is necessary for correct cell type specification and patterning du
Ndm, a coiled-coil domain protein that suppresses macropinocytosis and has effects on cell migration
Publikováno v:
Molecular Biology of the Cell
The Ndm protein colocalizes with coronin and is necessary for formation of rounded lamellipodia and cell spreading. Ndm-null cells show increased endocytosis and lamellipodia that break up into endocytic cups. The protein functions to limit endocytos
Publikováno v:
Development. 129:2381-2389
The cellular slime mold, Dictyostelium discoideum is a non-metazoan organism, yet we now demonstrate that a disintegrin domain-containing protein, the product of the ampA gene, plays a role in cell type specification. Disintegrin domain-containing pr
Autor:
Timothy R. Varney, Chere' Petty, Jayne Dolman, Hoa N. Ho, Daphne D. Blumberg, Elisabeth Casademunt
Publikováno v:
Developmental Biology. 243:226-248
The Dictyostelium protein AmpA (adhesion modulation protein A) is encoded by the gene originally identified by the D11 cDNA clone. AmpA contains repeated domains homologous to a variety of proteins that influence cell adhesion. The protein accumulate
Publikováno v:
Journal of Muscle Research and Cell Motility. 23:817-828
Proteins containing disintegrin domains play a variety of roles in regulating processes involving adhesion, migration and cell type specification during development of many metazoan organisms. Most disintegrin domain containing proteins belong to the
Autor:
Ameeta K. Agarwal, Daphne D. Blumberg
Publikováno v:
Differentiation. 64:247-254
Starvation for amino acids initiates the developmental program in the cellular slime mold, Dictyostelium discoideum [19, 20]. One of the earliest developmental events is the decline in ribosomal protein synthesis [2, 17, 29, 30]. The ribosomal protei
Publikováno v:
Eukaryotic cell. 11(4)
The ampA gene plays a role in Dictyostelium discoideum cell migration. Loss of ampA function results in reduced ability of growing cells to migrate to folic acid and causes small plaques on bacterial lawns, while overexpression of AmpA results in a r
Autor:
Daphne D. Blumberg, Bradley K. Yoder
Publikováno v:
Developmental Biology. 163:38-48
The cAMP-inducible prespore gene, PL3, encodes a protein which is a novel component of the spore coat. Unlike the well-characterized spore coat proteins (SP60, SP70, and SP96) which are found in the outer layer of the coat, the PL3 gene product is lo
Publikováno v:
Developmental Genetics. 12:65-77
Micrococcal nuclease digestion of chromatin from growing cells reveals a structural organization which differs for genes transcribed at diverse rates. The late cAMP dependent prespore genes which are not transcribed in growing cells are found in grow