Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Daozhong Jin"'
Publikováno v:
The Journal of Neuroscience. 43:3933-3948
The spinal dorsal horn contains vesicular glutamate transporter-2 (VGluT2)-expressing excitatory neurons and vesicular GABA transporter (VGAT)-expressing inhibitory neurons, which normally have different roles in nociceptive transmission. Spinal glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d765a6413708f982831e91c623a8b9e0
https://doi.org/10.1523/jneurosci.0183-23.2023
https://doi.org/10.1523/jneurosci.0183-23.2023
Autor:
Jixiang Zhang, Shao-Rui Chen, Meng-Hua Zhou, Daozhong Jin, Hong Chen, Li Wang, Ronald A. DePinho, Hui-Lin Pan
Publikováno v:
J Neurosci
α2δ-1 (encoded by theCacna2d1gene) is a newly discovered NMDA receptor-interacting protein and is the therapeutic target of gabapentinoids (e.g., gabapentin and pregabalin) frequently used for treating patients with neuropathic pain. Nerve injury c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26980e7277e10589488290ced53d4c2b
https://doi.org/10.1523/jneurosci.0735-22.2022
https://doi.org/10.1523/jneurosci.0735-22.2022
Publikováno v:
Journal of Neuroscience; 8/2/2023, Vol. 43 Issue 31, p5593-5607, 15p
Publikováno v:
J Neurosci
Long-term potentiation (LTP) and long-term depression (LTD) in the spinal dorsal horn reflect activity-dependent synaptic plasticity and central sensitization in chronic pain. Tetanic high-frequency stimulation is commonly used to induce LTP in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ef178f05dcb6611eafea087a82369f
https://doi.org/10.1523/jneurosci.1968-21.2021
https://doi.org/10.1523/jneurosci.1968-21.2021
Publikováno v:
Journal of Neuroscience; 12/14/2022, Vol. 42 Issue 50, p9315-9329, 15p
Publikováno v:
J Neurosci
Systemic treatment with resiniferatoxin (RTX) induces small-fiber sensory neuropathy by damaging TRPV1-expressing primary sensory neurons and causes distinct thermal sensory impairment and tactile allodynia, which resemble the unique clinical feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d40851e47a70433d3aeac56c4b276cb
https://doi.org/10.1523/jneurosci.0303-21.2021
https://doi.org/10.1523/jneurosci.0303-21.2021
Publikováno v:
Journal of neurochemistryREFERENCES.
Glutamate NMDA receptors (NMDARs) in the nucleus accumbens (NAc) are critically involved in drug dependence and reward. α2δ-1 is a newly discovered NMDAR-interacting protein that promotes synaptic trafficking of NMDARs independently of its conventi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15171ee7eca3bae9d88e28c5e6dc397
https://pubmed.ncbi.nlm.nih.gov/36222452
https://pubmed.ncbi.nlm.nih.gov/36222452
Publikováno v:
Neuropharmacology. 217
δ-Opioid receptors (DORs, encoded by the Oprd1 gene) are expressed throughout the peripheral and central nervous system, and DOR stimulation reduces nociception. Previous studies suggest that DORs promote the development of analgesic tolerance of μ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a515db076351827095b2d700f037d84d
https://pubmed.ncbi.nlm.nih.gov/35917874
https://pubmed.ncbi.nlm.nih.gov/35917874
Publikováno v:
Journal of Neuroscience; 1/19/2022, Vol. 42 Issue 3, p513-527, 15p
Publikováno v:
Journal of Neuroscience; 7/7/2021, Vol. 41 Issue 27, p5963-5978, 16p