Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Daoyun Ji"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Navigation is one of the most fundamental skills of animals. During spatial navigation, grid cells in the medial entorhinal cortex process speed and direction of the animal to map the environment. Hippocampal place cells, in turn, encode pla
Externí odkaz:
https://doaj.org/article/565b66093f784e2cb5a0255d437454cd
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106931- (2023)
Summary: Neuronal impairment is a characteristic of Alzheimer’s disease (AD), but its effect on neural activity dynamics underlying memory deficits is unclear. Here, we studied the effects of synaptic impairment on neural activities associated with
Externí odkaz:
https://doaj.org/article/e08a2d1d4f2e4641a006f9325183e480
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101501- (2022)
Summary: Social observation facilitates spatial learning by activation of hippocampal place cell patterns. Here, we describe an observational spatial working memory task to investigate the neural circuits underlying observational learning. This appro
Externí odkaz:
https://doaj.org/article/e2ecc82aec7f4fe3a7707db468393256
Publikováno v:
Frontiers in Computational Neuroscience, Vol 16 (2022)
Neurons in the brain are submerged into oscillating extracellular potential produced by synchronized synaptic currents. The dynamics of these oscillations is one of the principal characteristics of neurophysiological activity, broadly studied in basi
Externí odkaz:
https://doaj.org/article/70c66907aeed4482b93fcfafd385fa87
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109714- (2021)
Summary: Lysergic acid diethylamide (LSD) produces hallucinations, which are perceptions uncoupled from the external environment. How LSD alters neuronal activities in vivo that underlie abnormal perceptions is unknown. Here, we show that when rats r
Externí odkaz:
https://doaj.org/article/6cf534eebe88436cbed70039f6d5c229
Autor:
Sile Hu, Davide Ciliberti, Andres D. Grosmark, Frédéric Michon, Daoyun Ji, Hector Penagos, György Buzsáki, Matthew A. Wilson, Fabian Kloosterman, Zhe Chen
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2635-2642.e5 (2018)
Summary: Uncovering spatial representations from large-scale ensemble spike activity in specific brain circuits provides valuable feedback in closed-loop experiments. We develop a graphics processing unit (GPU)-powered population-decoding system for
Externí odkaz:
https://doaj.org/article/e6a02c18a5e1458f87205008e64552b0
Autor:
Rong Zhao, Stacy D. Grunke, Madhusudhanan M. Keralapurath, Michael J. Yetman, Alexander Lam, Tang-Cheng Lee, Konstantinos Sousounis, Yongying Jiang, Deborah A. Swing, Lino Tessarollo, Daoyun Ji, Joanna L. Jankowsky
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 793-804 (2016)
The neural network of the temporal lobe is thought to provide a cognitive map of our surroundings. Functional analysis of this network has been hampered by coarse tools that often result in collateral damage to other circuits. We developed a chemogen
Externí odkaz:
https://doaj.org/article/3e04b15e05c74992a67a8fe47841b100
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Hippocampal place cells are key to spatial representation and spatial memory processing. They fire at specific locations in a space (place fields) and fire in precise patterns during theta sequences and during ripple-associated replay events. These p
Externí odkaz:
https://doaj.org/article/4e7f3042facb4f75a7ef43c72ad2a407
Publikováno v:
eLife, Vol 7 (2018)
The Mecp2+/- mouse model recapitulates many phenotypes of patients with Rett syndrome (RTT), including learning and memory deficits. It is unknown, however, how the disease state alters memory circuit functions in vivo in RTT mice. Here we recorded f
Externí odkaz:
https://doaj.org/article/56bf96e319d64501812ab4a3d363b0f8
Publikováno v:
Bio-Protocol, Vol 7, Iss 13 (2017)
Animals often learn through observing their conspecifics. However, the mechanisms of them obtaining useful knowledge during observation are beginning to be understood. This protocol describes a novel social observation task to test the ‘local enhan
Externí odkaz:
https://doaj.org/article/45b3f980b5044a4bad69a2efb7fd4953